9GMO
eIF6-bound pre-60S large ribosomal subunit incorporating mutant uL16
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00028 |
| Number of Residues | 23 |
| Details | ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cit..CrvaFrdadmqraHyktdwH |
| Chain | Residue | Details |
| 0 | CYS6-HIS28 | |
| 0 | CYS69-HIS91 |
| site_id | PS00049 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI |
| Chain | Residue | Details |
| P | ALA79-ILE105 |
| site_id | PS00050 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV |
| Chain | Residue | Details |
| R | LYS134-VAL149 |
| site_id | PS00051 |
| Number of Residues | 17 |
| Details | RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR |
| Chain | Residue | Details |
| f | LYS30-ARG46 |
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| g | LYS27-ASP52 |
| site_id | PS00358 |
| Number of Residues | 17 |
| Details | RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT |
| Chain | Residue | Details |
| q | LEU40-THR56 |
| site_id | PS00464 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL |
| Chain | Residue | Details |
| J | ARG126-LEU150 |
| site_id | PS00467 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE |
| Chain | Residue | Details |
| D | PRO197-GLU208 |
| site_id | PS00474 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR |
| Chain | Residue | Details |
| E | PHE211-ARG234 |
| site_id | PS00475 |
| Number of Residues | 32 |
| Details | RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIksvG |
| Chain | Residue | Details |
| U | LYS110-GLY141 |
| site_id | PS00526 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP |
| Chain | Residue | Details |
| L | GLN7-PRO26 |
| site_id | PS00579 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV |
| Chain | Residue | Details |
| b | LYS43-VAL57 |
| site_id | PS00580 |
| Number of Residues | 21 |
| Details | RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG |
| Chain | Residue | Details |
| Y | PHE20-GLY40 |
| site_id | PS00634 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLrQifNgTfvklnkasinMLriVepYI |
| Chain | Residue | Details |
| m | VAL108-ILE140 |
| site_id | PS00687 |
| Number of Residues | 8 |
| Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV |
| Chain | Residue | Details |
| F | GLY15-VAL22 |
| site_id | PS00700 |
| Number of Residues | 22 |
| Details | RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK |
| Chain | Residue | Details |
| o | GLN163-LYS184 |
| site_id | PS00709 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqtLKmiRqGkaKlVIL |
| Chain | Residue | Details |
| W | SER24-LEU48 |
| site_id | PS00783 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG |
| Chain | Residue | Details |
| I | VAL84-GLY107 |
| site_id | PS00939 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH |
| Chain | Residue | Details |
| F | ASN116-HIS142 |
| site_id | PS00993 |
| Number of Residues | 21 |
| Details | RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLaIiDpG |
| Chain | Residue | Details |
| W | GLU80-GLY100 |
| site_id | PS01073 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGykIyPGhGrrYaRtD |
| Chain | Residue | Details |
| Q | PHE8-ASP25 |
| site_id | PS01077 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG |
| Chain | Residue | Details |
| d | GLY4-GLY23 |
| site_id | PS01082 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciIkGKarLG |
| Chain | Residue | Details |
| n | CYS174-GLY191 |
| site_id | PS01104 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG |
| Chain | Residue | Details |
| r | ARG71-GLY85 |
| site_id | PS01105 |
| Number of Residues | 22 |
| Details | RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP |
| Chain | Residue | Details |
| Z | GLY72-PRO93 |
| site_id | PS01106 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM |
| Chain | Residue | Details |
| K | LYS49-MET66 |
| site_id | PS01107 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF |
| Chain | Residue | Details |
| T | GLY125-PHE136 |
| site_id | PS01108 |
| Number of Residues | 19 |
| Details | RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV |
| Chain | Residue | Details |
| S | ASP52-VAL70 |
| site_id | PS01144 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG |
| Chain | Residue | Details |
| X | VAL62-GLY76 |
| site_id | PS01145 |
| Number of Residues | 14 |
| Details | RIBOSOMAL_L34E Ribosomal protein L34e signature. TaSnKtrlsRTPGN |
| Chain | Residue | Details |
| a | THR15-ASN28 |
| site_id | PS01170 |
| Number of Residues | 19 |
| Details | RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K |
| Chain | Residue | Details |
| H | ASN182-LYS200 |
| site_id | PS01171 |
| Number of Residues | 26 |
| Details | RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG |
| Chain | Residue | Details |
| N | GLY37-GLY62 |
| site_id | PS01172 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLRleC |
| Chain | Residue | Details |
| i | LYS61-CYS72 |
| site_id | PS01190 |
| Number of Residues | 11 |
| Details | RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK |
| Chain | Residue | Details |
| c | PRO52-LYS62 |
| site_id | PS01194 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG |
| Chain | Residue | Details |
| l | ASP46-GLY69 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylalanine => ECO:0000269|PubMed:12962325, ECO:0000269|PubMed:25489052, ECO:0000269|Ref.6, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712 |
| Chain | Residue | Details |
| I | ALA2 | |
| H | LYS207 | |
| L | ARG38 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Citrulline => ECO:0000250|UniProtKB:P19253 |
| Chain | Residue | Details |
| I | ARG59 | |
| I | ARG140 | |
| F | LYS333 | |
| D | LYS234 | |
| D | LYS250 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by ZIPK/DAPK3 => ECO:0000269|PubMed:18995835 |
| Chain | Residue | Details |
| I | SER77 | |
| p | LYS188 | |
| n | LYS20 | |
| n | LYS21 | |
| n | LYS48 | |
| n | LYS125 | |
| n | LYS245 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| I | LYS191 | |
| F | LYS353 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| G | THR232 | |
| E | LYS366 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692 |
| Chain | Residue | Details |
| G | SER272 | |
| r | LYS145 | |
| q | LYS154 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25114211 |
| Chain | Residue | Details |
| G | LYS220 | |
| E | LYS224 | |
| E | LYS226 | |
| E | LYS386 | |
| E | LYS393 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | MOD_RES: Citrulline => ECO:0000250|UniProtKB:Q9D8E6 |
| Chain | Residue | Details |
| F | ARG300 | |
| E | LYS399 | |
| Q | LYS35 | |
| Q | LYS147 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:Q9D8E6 |
| Chain | Residue | Details |
| F | LYS364 | |
| E | LYS366 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| F | SER365 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| F | LYS239 | |
| F | LYS327 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate => ECO:0007744|PubMed:25114211 |
| Chain | Residue | Details |
| g | LYS33 | |
| F | LYS364 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 1 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106 |
| Chain | Residue | Details |
| g | LYS63 |
