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9GDR

Cryo-EM structure of Vibrio cholerae RNA polymerase Transcription Activation Complex with TcpP transcription factor and a toxT promoter DNA fragment

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003899molecular_functionDNA-directed RNA polymerase activity
A0005737cellular_componentcytoplasm
A0006351biological_processDNA-templated transcription
A0034062molecular_function5'-3' RNA polymerase activity
B0003677molecular_functionDNA binding
B0003899molecular_functionDNA-directed RNA polymerase activity
B0005737cellular_componentcytoplasm
B0006351biological_processDNA-templated transcription
B0034062molecular_function5'-3' RNA polymerase activity
C0003677molecular_functionDNA binding
C0003899molecular_functionDNA-directed RNA polymerase activity
C0006351biological_processDNA-templated transcription
C0034062molecular_function5'-3' RNA polymerase activity
D0000287molecular_functionmagnesium ion binding
D0003677molecular_functionDNA binding
D0003899molecular_functionDNA-directed RNA polymerase activity
D0005829cellular_componentcytosol
D0006351biological_processDNA-templated transcription
D0008270molecular_functionzinc ion binding
D0034062molecular_function5'-3' RNA polymerase activity
E0003677molecular_functionDNA binding
E0003899molecular_functionDNA-directed RNA polymerase activity
E0006351biological_processDNA-templated transcription
E0034062molecular_function5'-3' RNA polymerase activity
F0003677molecular_functionDNA binding
F0005737cellular_componentcytoplasm
F0006352biological_processDNA-templated transcription initiation
F0010468biological_processregulation of gene expression
F0016987molecular_functionsigma factor activity
F2000142biological_processregulation of DNA-templated transcription initiation
G0003677molecular_functionDNA binding
G0003899molecular_functionDNA-directed RNA polymerase activity
G0005737cellular_componentcytoplasm
G0006351biological_processDNA-templated transcription
G0034062molecular_function5'-3' RNA polymerase activity
Functional Information from PROSITE/UniProt
site_idPS00715
Number of Residues14
DetailsSIGMA70_1 Sigma-70 factors family signature 1. DLIQeGnIGLMkAV
ChainResidueDetails
FASP411-VAL424

site_idPS00716
Number of Residues27
DetailsSIGMA70_2 Sigma-70 factors family signature 2. TleEVGkqfdVTrerIrQIEakaLrkL
ChainResidueDetails
FTHR580-LEU606

site_idPS01166
Number of Residues13
DetailsRNA_POL_BETA RNA polymerases beta chain signature. GdKMAGrHGNKGV
ChainResidueDetails
CGLY1063-VAL1075

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI3
Number of Residues11
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

251174

PDB entries from 2026-03-25

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