9G9N

Lipid III flippase WzxE with NB10 and NB7 nanobodies in inward-facing conformation - crystal 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0009246	biological_process	enterobacterial common antigen biosynthetic process
A	0016020	cellular_component	membrane
A	0034204	biological_process	lipid translocation
A	0140303	molecular_function	intramembrane lipid transporter activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	240
Details	TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_02024

Chain	Residue	Details
A	ILE18-GLY38
A	ALA335-ILE355
A	PHE371-ALA391
A	GLN392-TRP412
A	LEU46-VAL66
A	ALA85-ILE105
A	VAL122-PHE142
A	ALA145-VAL165
A	ALA175-ILE195
A	LEU217-MET237
A	ILE260-LEU280
A	ALA303-LEU323

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site_id	SWS_FT_FI2
Number of Residues	60
Details	TOPO_DOM: Periplasmic => ECO:0000305

Chain	Residue	Details
A	LEU39-GLN45
A	SER106-LEU121
A	SER166-GLY174
A	MET238-SER259
A	SER324-PHE334

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site_id	SWS_FT_FI3
Number of Residues	73
Details	TOPO_DOM: Cytoplasmic => ECO:0000305

Chain	Residue	Details
A	ALA67-SER84
A	ARG143-ASP144
A	LYS196-GLN216
A	SER281-PRO302
A	ALA356-GLN370

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site_id	SWS_FT_FI4
Number of Residues	3
Details	TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:15919996

Chain	Residue	Details
A	ARG413-ALA416

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