9FSH

Crystal structure of the HECT domain of Smurf 2 in complex with inhibitor 8

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004842	molecular_function	ubiquitin-protein transferase activity

Functional Information from PROSITE/UniProt

site_id	PS01159
Number of Residues	26
Details	WW_DOMAIN_1 WW/rsp5/WWP domain signature. Weirntatgrv.YFvdhnnrtTQFTDP

Chain	Residue	Details
A	TRP303-PRO328

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00104","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"38016474","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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