9FQ1

Structure of the disease-causing mutant P20S of human KCTD1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003714	molecular_function	transcription corepressor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0008134	molecular_function	transcription factor binding
A	0042802	molecular_function	identical protein binding
A	0045746	biological_process	negative regulation of Notch signaling pathway
A	0045879	biological_process	negative regulation of smoothened signaling pathway
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0051260	biological_process	protein homooligomerization
A	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
B	0003714	molecular_function	transcription corepressor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0008134	molecular_function	transcription factor binding
B	0042802	molecular_function	identical protein binding
B	0045746	biological_process	negative regulation of Notch signaling pathway
B	0045879	biological_process	negative regulation of smoothened signaling pathway
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0051260	biological_process	protein homooligomerization
B	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
C	0003714	molecular_function	transcription corepressor activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0008134	molecular_function	transcription factor binding
C	0042802	molecular_function	identical protein binding
C	0045746	biological_process	negative regulation of Notch signaling pathway
C	0045879	biological_process	negative regulation of smoothened signaling pathway
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0051260	biological_process	protein homooligomerization
C	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
D	0003714	molecular_function	transcription corepressor activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0008134	molecular_function	transcription factor binding
D	0042802	molecular_function	identical protein binding
D	0045746	biological_process	negative regulation of Notch signaling pathway
D	0045879	biological_process	negative regulation of smoothened signaling pathway
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0051260	biological_process	protein homooligomerization
D	0090090	biological_process	negative regulation of canonical Wnt signaling pathway
E	0003714	molecular_function	transcription corepressor activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0008134	molecular_function	transcription factor binding
E	0042802	molecular_function	identical protein binding
E	0045746	biological_process	negative regulation of Notch signaling pathway
E	0045879	biological_process	negative regulation of smoothened signaling pathway
E	0045892	biological_process	negative regulation of DNA-templated transcription
E	0051260	biological_process	protein homooligomerization
E	0090090	biological_process	negative regulation of canonical Wnt signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	280
Details	Domain: {"description":"BTB"}

Chain

Residue

Details

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