9FEH
Crystal structure of SARS-CoV-2 nsp14 methyltransferase domain in complex with the STM957 inhibitor
This is a non-PDB format compatible entry.
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Breakpoint for translocation to form ETV6-MDS2 in MDS |
| Chain | Residue | Details |
| A | LEU227 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Breakpoint for translocation to form PAX5-ETV6 |
| Chain | Residue | Details |
| A | ARG228 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01299 |
| Chain | Residue | Details |
| A | ASP331 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:36546776 |
| Chain | Residue | Details |
| A | CYS452 | |
| A | CYS477 | |
| A | CYS484 | |
| A | HIS487 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by 3CL-PRO => ECO:0000250|UniProtKB:P0C6V3 |
| Chain | Residue | Details |
| A | GLN527 |
