9FD2

Structure of Pol II-TC-NER-STK19 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0001172	biological_process	RNA-templated transcription
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed RNA polymerase activity
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0005737	cellular_component	cytoplasm
A	0006351	biological_process	DNA-templated transcription
A	0006366	biological_process	transcription by RNA polymerase II
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0000781	cellular_component	chromosome, telomeric region
B	0001172	biological_process	RNA-templated transcription
B	0003677	molecular_function	DNA binding
B	0003682	molecular_function	chromatin binding
B	0003899	molecular_function	DNA-directed RNA polymerase activity
B	0003968	molecular_function	RNA-directed RNA polymerase activity
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005665	cellular_component	RNA polymerase II, core complex
B	0006351	biological_process	DNA-templated transcription
B	0006366	biological_process	transcription by RNA polymerase II
B	0008270	molecular_function	zinc ion binding
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0016787	molecular_function	hydrolase activity
B	0032549	molecular_function	ribonucleoside binding
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0046872	molecular_function	metal ion binding
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0003677	molecular_function	DNA binding
C	0003899	molecular_function	DNA-directed RNA polymerase activity
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005665	cellular_component	RNA polymerase II, core complex
C	0005829	cellular_component	cytosol
C	0006351	biological_process	DNA-templated transcription
C	0006366	biological_process	transcription by RNA polymerase II
C	0046983	molecular_function	protein dimerization activity
D	0000166	molecular_function	nucleotide binding
D	0000428	cellular_component	DNA-directed RNA polymerase complex
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0006352	biological_process	DNA-templated transcription initiation
D	0030880	cellular_component	RNA polymerase complex
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed RNA polymerase activity
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005665	cellular_component	RNA polymerase II, core complex
E	0005666	cellular_component	RNA polymerase III complex
E	0005736	cellular_component	RNA polymerase I complex
E	0006351	biological_process	DNA-templated transcription
E	0006362	biological_process	transcription elongation by RNA polymerase I
E	0006366	biological_process	transcription by RNA polymerase II
E	0042797	biological_process	tRNA transcription by RNA polymerase III
F	0000428	cellular_component	DNA-directed RNA polymerase complex
F	0001650	cellular_component	fibrillar center
F	0003677	molecular_function	DNA binding
F	0003899	molecular_function	DNA-directed RNA polymerase activity
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005665	cellular_component	RNA polymerase II, core complex
F	0005666	cellular_component	RNA polymerase III complex
F	0005736	cellular_component	RNA polymerase I complex
F	0006351	biological_process	DNA-templated transcription
F	0006360	biological_process	transcription by RNA polymerase I
F	0006366	biological_process	transcription by RNA polymerase II
F	0042797	biological_process	tRNA transcription by RNA polymerase III
G	0000428	cellular_component	DNA-directed RNA polymerase complex
G	0003676	molecular_function	nucleic acid binding
G	0005634	cellular_component	nucleus
G	0006351	biological_process	DNA-templated transcription
G	0006352	biological_process	DNA-templated transcription initiation
H	0000428	cellular_component	DNA-directed RNA polymerase complex
H	0003899	molecular_function	DNA-directed RNA polymerase activity
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005665	cellular_component	RNA polymerase II, core complex
H	0005666	cellular_component	RNA polymerase III complex
H	0005736	cellular_component	RNA polymerase I complex
H	0006351	biological_process	DNA-templated transcription
I	0000428	cellular_component	DNA-directed RNA polymerase complex
I	0001193	biological_process	maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
I	0003676	molecular_function	nucleic acid binding
I	0003899	molecular_function	DNA-directed RNA polymerase activity
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005665	cellular_component	RNA polymerase II, core complex
I	0005730	cellular_component	nucleolus
I	0006283	biological_process	transcription-coupled nucleotide-excision repair
I	0006351	biological_process	DNA-templated transcription
I	0006366	biological_process	transcription by RNA polymerase II
I	0006367	biological_process	transcription initiation at RNA polymerase II promoter
I	0008270	molecular_function	zinc ion binding
I	0046872	molecular_function	metal ion binding
J	0000428	cellular_component	DNA-directed RNA polymerase complex
J	0003677	molecular_function	DNA binding
J	0003899	molecular_function	DNA-directed RNA polymerase activity
J	0005634	cellular_component	nucleus
J	0005665	cellular_component	RNA polymerase II, core complex
J	0005666	cellular_component	RNA polymerase III complex
J	0005736	cellular_component	RNA polymerase I complex
J	0006351	biological_process	DNA-templated transcription
J	0006360	biological_process	transcription by RNA polymerase I
J	0006366	biological_process	transcription by RNA polymerase II
J	0008270	molecular_function	zinc ion binding
J	0042797	biological_process	tRNA transcription by RNA polymerase III
J	0046872	molecular_function	metal ion binding
K	0000428	cellular_component	DNA-directed RNA polymerase complex
K	0003677	molecular_function	DNA binding
K	0003899	molecular_function	DNA-directed RNA polymerase activity
K	0005634	cellular_component	nucleus
K	0005665	cellular_component	RNA polymerase II, core complex
K	0006351	biological_process	DNA-templated transcription
K	0006366	biological_process	transcription by RNA polymerase II
K	0046983	molecular_function	protein dimerization activity
L	0000428	cellular_component	DNA-directed RNA polymerase complex
L	0003677	molecular_function	DNA binding
L	0003899	molecular_function	DNA-directed RNA polymerase activity
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005665	cellular_component	RNA polymerase II, core complex
L	0005666	cellular_component	RNA polymerase III complex
L	0005730	cellular_component	nucleolus
L	0005736	cellular_component	RNA polymerase I complex
L	0006351	biological_process	DNA-templated transcription
L	0006366	biological_process	transcription by RNA polymerase II
L	0008270	molecular_function	zinc ion binding
L	0046872	molecular_function	metal ion binding
a	0000012	biological_process	single strand break repair
a	0000109	cellular_component	nucleotide-excision repair complex
a	0000209	biological_process	protein polyubiquitination
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005694	cellular_component	chromosome
a	0006281	biological_process	DNA repair
a	0006283	biological_process	transcription-coupled nucleotide-excision repair
a	0006974	biological_process	DNA damage response
a	0006979	biological_process	response to oxidative stress
a	0009411	biological_process	response to UV
a	0010165	biological_process	response to X-ray
a	0010996	biological_process	response to auditory stimulus
a	0016363	cellular_component	nuclear matrix
a	0016567	biological_process	protein ubiquitination
a	0031464	cellular_component	Cul4A-RING E3 ubiquitin ligase complex
a	0032991	cellular_component	protein-containing complex
a	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
a	0043204	cellular_component	perikaryon
a	0051865	biological_process	protein autoubiquitination
a	0080008	cellular_component	Cul4-RING E3 ubiquitin ligase complex
a	0090262	biological_process	regulation of transcription-coupled nucleotide-excision repair
a	0090734	cellular_component	site of DNA damage
a	0097680	biological_process	double-strand break repair via classical nonhomologous end joining
a	1990756	molecular_function	ubiquitin-like ligase-substrate adaptor activity
b	0000781	cellular_component	chromosome, telomeric region
b	0003676	molecular_function	nucleic acid binding
b	0003677	molecular_function	DNA binding
b	0003684	molecular_function	damaged DNA binding
b	0005515	molecular_function	protein binding
b	0005615	cellular_component	extracellular space
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005730	cellular_component	nucleolus
b	0005737	cellular_component	cytoplasm
b	0006281	biological_process	DNA repair
b	0006289	biological_process	nucleotide-excision repair
b	0006511	biological_process	ubiquitin-dependent protein catabolic process
b	0006915	biological_process	apoptotic process
b	0006974	biological_process	DNA damage response
b	0007056	biological_process	spindle assembly involved in female meiosis
b	0010498	biological_process	proteasomal protein catabolic process
b	0016055	biological_process	Wnt signaling pathway
b	0016567	biological_process	protein ubiquitination
b	0019076	biological_process	viral release from host cell
b	0030674	molecular_function	protein-macromolecule adaptor activity
b	0031464	cellular_component	Cul4A-RING E3 ubiquitin ligase complex
b	0031465	cellular_component	Cul4B-RING E3 ubiquitin ligase complex
b	0032991	cellular_component	protein-containing complex
b	0034644	biological_process	cellular response to UV
b	0035234	biological_process	ectopic germ cell programmed cell death
b	0035861	cellular_component	site of double-strand break
b	0042752	biological_process	regulation of circadian rhythm
b	0043066	biological_process	negative regulation of apoptotic process
b	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
b	0044725	biological_process	epigenetic programming in the zygotic pronuclei
b	0044877	molecular_function	protein-containing complex binding
b	0045070	biological_process	positive regulation of viral genome replication
b	0045722	biological_process	positive regulation of gluconeogenesis
b	0045732	biological_process	positive regulation of protein catabolic process
b	0046726	biological_process	positive regulation by virus of viral protein levels in host cell
b	0048511	biological_process	rhythmic process
b	0051093	biological_process	negative regulation of developmental process
b	0051702	biological_process	biological process involved in interaction with symbiont
b	0070062	cellular_component	extracellular exosome
b	0070914	biological_process	UV-damage excision repair
b	0071987	molecular_function	WD40-repeat domain binding
b	0080008	cellular_component	Cul4-RING E3 ubiquitin ligase complex
b	0097225	cellular_component	sperm midpiece
b	0097228	cellular_component	sperm principal piece
b	0097229	cellular_component	sperm end piece
b	0097602	molecular_function	cullin family protein binding
b	0160072	molecular_function	ubiquitin ligase complex scaffold activity
b	1901990	biological_process	regulation of mitotic cell cycle phase transition
b	2000242	biological_process	negative regulation of reproductive process
c	0000209	biological_process	protein polyubiquitination
c	0005515	molecular_function	protein binding
c	0005654	cellular_component	nucleoplasm
c	0016567	biological_process	protein ubiquitination
c	0032434	biological_process	regulation of proteasomal ubiquitin-dependent protein catabolic process
c	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
c	0080008	cellular_component	Cul4-RING E3 ubiquitin ligase complex
d	0000993	molecular_function	RNA polymerase II complex binding
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005694	cellular_component	chromosome
d	0006281	biological_process	DNA repair
d	0006283	biological_process	transcription-coupled nucleotide-excision repair
d	0006325	biological_process	chromatin organization
d	0006974	biological_process	DNA damage response
d	0008270	molecular_function	zinc ion binding
d	0009411	biological_process	response to UV
d	0016567	biological_process	protein ubiquitination
d	0046872	molecular_function	metal ion binding
d	0090734	cellular_component	site of DNA damage
d	0140463	molecular_function	chromatin-protein adaptor activity
d	0140870	molecular_function	RNA polymerase inhibitor activity
e	0000012	biological_process	single strand break repair
e	0000077	biological_process	DNA damage checkpoint signaling
e	0000166	molecular_function	nucleotide binding
e	0000303	biological_process	response to superoxide
e	0003677	molecular_function	DNA binding
e	0003678	molecular_function	DNA helicase activity
e	0003682	molecular_function	chromatin binding
e	0004386	molecular_function	helicase activity
e	0005515	molecular_function	protein binding
e	0005524	molecular_function	ATP binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005694	cellular_component	chromosome
e	0005730	cellular_component	nucleolus
e	0006281	biological_process	DNA repair
e	0006283	biological_process	transcription-coupled nucleotide-excision repair
e	0006284	biological_process	base-excision repair
e	0006290	biological_process	pyrimidine dimer repair
e	0006338	biological_process	chromatin remodeling
e	0006362	biological_process	transcription elongation by RNA polymerase I
e	0006366	biological_process	transcription by RNA polymerase II
e	0006974	biological_process	DNA damage response
e	0006979	biological_process	response to oxidative stress
e	0007254	biological_process	JNK cascade
e	0007399	biological_process	nervous system development
e	0008023	cellular_component	transcription elongation factor complex
e	0008094	molecular_function	ATP-dependent activity, acting on DNA
e	0008630	biological_process	intrinsic apoptotic signaling pathway in response to DNA damage
e	0009411	biological_process	response to UV
e	0009636	biological_process	response to toxic substance
e	0010165	biological_process	response to X-ray
e	0010224	biological_process	response to UV-B
e	0010332	biological_process	response to gamma radiation
e	0016787	molecular_function	hydrolase activity
e	0016887	molecular_function	ATP hydrolysis activity
e	0022008	biological_process	neurogenesis
e	0030182	biological_process	neuron differentiation
e	0030296	molecular_function	protein tyrosine kinase activator activity
e	0031175	biological_process	neuron projection development
e	0032784	biological_process	regulation of DNA-templated transcription elongation
e	0032786	biological_process	positive regulation of DNA-templated transcription, elongation
e	0034243	biological_process	regulation of transcription elongation by RNA polymerase II
e	0035264	biological_process	multicellular organism growth
e	0042262	biological_process	DNA protection
e	0045494	biological_process	photoreceptor cell maintenance
e	0045739	biological_process	positive regulation of DNA repair
e	0045943	biological_process	positive regulation of transcription by RNA polymerase I
e	0045944	biological_process	positive regulation of transcription by RNA polymerase II
e	0045945	biological_process	positive regulation of transcription by RNA polymerase III
e	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
e	0071168	biological_process	protein localization to chromatin
e	0090734	cellular_component	site of DNA damage
e	0097680	biological_process	double-strand break repair via classical nonhomologous end joining
e	0110016	cellular_component	B-WICH complex
e	0140463	molecular_function	chromatin-protein adaptor activity
e	0140658	molecular_function	ATP-dependent chromatin remodeler activity
e	0140664	molecular_function	ATP-dependent DNA damage sensor activity
e	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
e	2001033	biological_process	negative regulation of double-strand break repair via nonhomologous end joining
f	0000993	molecular_function	RNA polymerase II complex binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005694	cellular_component	chromosome
f	0006281	biological_process	DNA repair
f	0006283	biological_process	transcription-coupled nucleotide-excision repair
f	0006368	biological_process	transcription elongation by RNA polymerase II
f	0006974	biological_process	DNA damage response
f	0008023	cellular_component	transcription elongation factor complex
f	0030674	molecular_function	protein-macromolecule adaptor activity
g	0003677	molecular_function	DNA binding
g	0003690	molecular_function	double-stranded DNA binding
g	0003723	molecular_function	RNA binding
g	0003725	molecular_function	double-stranded RNA binding
g	0004674	molecular_function	protein serine/threonine kinase activity
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005737	cellular_component	cytoplasm
g	0006281	biological_process	DNA repair
g	0006974	biological_process	DNA damage response
g	0016607	cellular_component	nuclear speck
g	0042803	molecular_function	protein homodimerization activity
g	0046579	biological_process	positive regulation of Ras protein signal transduction
g	1903518	biological_process	positive regulation of single strand break repair

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DNDPSDYVEqdDI

Chain	Residue	Details
C	ASP136-ILE148

---

site_id	PS00115
Number of Residues	7
Details	RNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPA

Chain	Residue	Details
A	TYR1593-ALA1599
A	TYR1671-SER1677
A	TYR1678-SER1684
A	TYR1685-SER1691
A	TYR1692-SER1698
A	TYR1699-SER1705
A	TYR1706-SER1712
A	TYR1713-SER1719
A	TYR1720-SER1726
A	TYR1727-SER1733
A	TYR1734-SER1740
A	TYR1615-SER1621
A	TYR1741-ASN1747
A	TYR1748-ASN1754
A	TYR1755-SER1761
A	TYR1762-SER1768
A	TYR1769-ASN1775
A	TYR1776-ASN1782
A	TYR1783-SER1789
A	TYR1790-SER1796
A	TYR1797-SER1803
A	TYR1818-SER1824
A	TYR1622-SER1628
A	TYR1825-SER1831
A	TYR1832-LYS1838
A	TYR1839-SER1845
A	TYR1853-LYS1859
A	TYR1860-LYS1866
A	TYR1867-LYS1873
A	TYR1874-THR1880
A	TYR1888-THR1894
A	TYR1902-LYS1908
A	TYR1909-THR1915
A	TYR1629-ASN1635
A	TYR1916-LYS1922
A	TYR1923-THR1929
A	TYR1930-LYS1936
A	TYR1947-THR1953
A	TYR1636-SER1642
A	TYR1643-SER1649
A	TYR1650-SER1656
A	TYR1657-SER1663
A	TYR1664-SER1670

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YVCTAPH

Chain	Residue	Details
I	TYR112-HIS118

---

site_id	PS00446
Number of Residues	41
Details	RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSIRRvfiaevpiiAidwVqidaNsSvlhDEfIAhRLGLIP

Chain	Residue	Details
C	ASN32-PRO72

---

site_id	PS00466
Number of Residues	38
Details	ZF_TFIIS_1 Zinc finger TFIIS-type signature. CqkCghkeavffqSHSARaEDAmrlyyvCtaph.CghrW

Chain	Residue	Details
I	CYS86-TRP123

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LATAsaDsRVKLWDV

Chain	Residue	Details
a	LEU202-VAL216
a	LEU260-SER274

---

site_id	PS01030
Number of Residues	27
Details	RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCQECNNMLypkedkenrillyaCrnC

Chain	Residue	Details
I	PHE16-CYS42

---

site_id	PS01110
Number of Residues	14
Details	RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPEHvvMtkEE

Chain	Residue	Details
E	HIS142-GLU155

---

site_id	PS01111
Number of Residues	15
Details	RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARvLGtRAlQ

Chain	Residue	Details
F	THR58-GLN72

---

site_id	PS01112
Number of Residues	10
Details	RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPVrCFTCG

Chain	Residue	Details
J	ILE2-GLY11

---

site_id	PS01154
Number of Residues	32
Details	RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. InkEdHTLgNiIksqLlkdpqVlfagYkvpHP

Chain	Residue	Details
K	ILE35-PRO66

---

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT

Chain	Residue	Details
B	GLY932-THR944

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI11
Number of Residues	25
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	42
Details	Zinc finger: {"description":"TFIIS-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10145","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"38316879","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8B3D","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	40
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	41
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	40
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	39
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	40
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	38
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	343
Details	Region: {"description":"WD repeat beta-propeller A"}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q9ESW0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	59
Details	Region: {"description":"Winged helix domain 2","evidences":[{"source":"PubMed","id":"38252411","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	3
Details	Motif: {"description":"DEAH box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	12
Details	Motif: {"description":"CSA-interacting motif (CIM)","evidences":[{"source":"PubMed","id":"32355176","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	27
Details	Zinc finger: {"description":"UVSSA-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01403","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"38316879","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01403","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"38316879","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8B3D","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---