9FCI
USP1 bound to KSQ-4279 and ubiquitin conjugated to FANCD2 (focused refinement)
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| D | 0001501 | biological_process | skeletal system development |
| D | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| D | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005654 | cellular_component | nucleoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006281 | biological_process | DNA repair |
| D | 0006282 | biological_process | regulation of DNA repair |
| D | 0006508 | biological_process | proteolysis |
| D | 0006974 | biological_process | DNA damage response |
| D | 0008233 | molecular_function | peptidase activity |
| D | 0008234 | molecular_function | cysteine-type peptidase activity |
| D | 0009411 | biological_process | response to UV |
| D | 0016579 | biological_process | protein deubiquitination |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0031647 | biological_process | regulation of protein stability |
| D | 0035520 | biological_process | monoubiquitinated protein deubiquitination |
| D | 0046427 | biological_process | positive regulation of receptor signaling pathway via JAK-STAT |
| D | 1904333 | biological_process | positive regulation of error-prone translesion synthesis |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"15694335","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16531995","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26388029","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10092","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10093","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q8BJQ2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 75 |
| Details | Domain: {"description":"Ubiquitin-like 9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00214","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
