9F6D
Human DNA polymerase epsilon bound to DNA and PCNA (open conformation)
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 57 |
| Details | DNA_BIND: DNA_BIND => ECO:0000255 |
| Chain | Residue | Details |
| B | ARG61-LYS80 | |
| C | ARG61-LYS80 | |
| D | ARG61-LYS80 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:19419956 |
| Chain | Residue | Details |
| B | LYS14 | |
| C | LYS14 | |
| D | LYS14 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| B | LYS77 | |
| B | LYS80 | |
| B | LYS248 | |
| C | LYS77 | |
| C | LYS80 | |
| C | LYS248 | |
| D | LYS77 | |
| D | LYS80 | |
| D | LYS248 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphotyrosine; by EGFR => ECO:0000269|PubMed:17115032 |
| Chain | Residue | Details |
| B | TYR211 | |
| C | TYR211 | |
| D | TYR211 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:17108083, ECO:0000269|PubMed:17130289 |
| Chain | Residue | Details |
| B | LYS164 | |
| C | LYS164 | |
| D | LYS164 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| B | LYS254 | |
| C | LYS254 | |
| D | LYS254 |
