9EY5
Crystal structure of human tyrosinase-related protein 1 (TYRP1) in complex with (S)-2,4-dihydroxyphenylalanine
Functional Information from PROSITE/UniProt
site_id | PS00022 |
Number of Residues | 12 |
Details | EGF_1 EGF-like domain signature 1. ChCngNfsGHnC |
Chain | Residue | Details |
A | CYS99-CYS110 |
site_id | PS00497 |
Number of Residues | 18 |
Details | TYROSINASE_1 Tyrosinase CuA-binding region signature. Hegpa.FLtWHRyhLlrlE |
Chain | Residue | Details |
A | HIS215-GLU232 |
site_id | PS00498 |
Number of Residues | 12 |
Details | TYROSINASE_2 Tyrosinase and hemocyanins CuB-binding region signature. DPiFVllHtftD |
Chain | Residue | Details |
A | ASP397-ASP408 |
site_id | PS01248 |
Number of Residues | 24 |
Details | EGF_LAM_1 Laminin-type EGF-like (LE) domain signature. Ch.CngnfsGhnCgtCrpg.Wrgaa...........C |
Chain | Residue | Details |
A | CYS99-CYS122 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:28661582, ECO:0007744|PDB:5M8L |
Chain | Residue | Details |
A | HIS192 | |
A | HIS215 | |
A | HIS224 | |
A | HIS377 | |
A | HIS381 | |
A | HIS404 |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:28661582, ECO:0007744|PDB:5M8L |
Chain | Residue | Details |
A | ASN96 | |
A | ASN104 | |
A | ASN181 | |
A | ASN304 | |
A | ASN350 | |
A | ASN385 |