9EP4

Structure of Integrator subcomplex INTS5/8/15

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000785	cellular_component	chromatin
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0016180	biological_process	snRNA processing
A	0032039	cellular_component	integrator complex
A	0034243	biological_process	regulation of transcription elongation by RNA polymerase II
A	0034472	biological_process	snRNA 3'-end processing
A	0071168	biological_process	protein localization to chromatin
A	0160232	cellular_component	INTAC complex
A	0160240	biological_process	RNA polymerase II transcription initiation surveillance
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0016020	cellular_component	membrane
B	0016180	biological_process	snRNA processing
B	0031965	cellular_component	nuclear membrane
B	0032039	cellular_component	integrator complex
B	0034243	biological_process	regulation of transcription elongation by RNA polymerase II
B	0034472	biological_process	snRNA 3'-end processing
B	0160232	cellular_component	INTAC complex
B	0160240	biological_process	RNA polymerase II transcription initiation surveillance
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0001654	biological_process	eye development
D	0005634	cellular_component	nucleus
D	0005694	cellular_component	chromosome
D	0007420	biological_process	brain development
D	0032039	cellular_component	integrator complex
D	0160232	cellular_component	INTAC complex
D	0160240	biological_process	RNA polymerase II transcription initiation surveillance

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	38
Details	Repeat: {"description":"TPR 1"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	33
Details	Repeat: {"description":"TPR 3"}

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Residue

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site_id	SWS_FT_FI3
Number of Residues	33
Details	Repeat: {"description":"TPR 4"}

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Residue

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site_id	SWS_FT_FI4
Number of Residues	5
Details	Motif: {"description":"WFEF motif","evidences":[{"source":"PubMed","id":"32966759","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	60
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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