9ENF

Human pseudouridine synthase 3 (PUS3 D118A mutant) and two pre-tRNA-Arg

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006400	biological_process	tRNA modification
A	0008033	biological_process	tRNA processing
A	0009982	molecular_function	pseudouridine synthase activity
A	0016853	molecular_function	isomerase activity
A	0031119	biological_process	tRNA pseudouridine synthesis
A	0160154	molecular_function	tRNA pseudouridine(38/39) synthase activity
A	1990481	biological_process	mRNA pseudouridine synthesis
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006400	biological_process	tRNA modification
B	0008033	biological_process	tRNA processing
B	0009982	molecular_function	pseudouridine synthase activity
B	0016853	molecular_function	isomerase activity
B	0031119	biological_process	tRNA pseudouridine synthesis
B	0160154	molecular_function	tRNA pseudouridine(38/39) synthase activity
B	1990481	biological_process	mRNA pseudouridine synthesis

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000250

Chain	Residue	Details
A	ALA118
B	ALA118

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	TYR195
B	TYR195

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: N-acetylalanine => ECO:0007744|PubMed:19413330

Chain	Residue	Details
A	ALA2
B	ALA2

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site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	THR456
A	THR468
B	THR456
B	THR468

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site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	THR466
B	THR466

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