9EM6
OPR3 variant Y364P in its dimeric form obtained without ammonium sulfate
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor => ECO:0000250 |
Chain | Residue | Details |
B | TYR190 | |
A | TYR190 |
site_id | SWS_FT_FI2 |
Number of Residues | 10 |
Details | BINDING: BINDING => ECO:0000269|PubMed:16983071, ECO:0000269|PubMed:19660473 |
Chain | Residue | Details |
B | PRO31 | |
A | GLY321 | |
B | GLY64 | |
B | GLN106 | |
B | ARG237 | |
B | GLY321 | |
A | PRO31 | |
A | GLY64 | |
A | GLN106 | |
A | ARG237 |
site_id | SWS_FT_FI3 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
B | HIS185 | |
B | ARG283 | |
B | GLY342 | |
A | HIS185 | |
A | ARG283 | |
A | GLY342 |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 697 |
Chain | Residue | Details |
B | HIS185 | electrostatic stabiliser |
B | HIS188 | electrostatic stabiliser |
B | TYR190 | proton shuttle (general acid/base) |
site_id | MCSA2 |
Number of Residues | 3 |
Details | M-CSA 697 |
Chain | Residue | Details |
A | HIS185 | electrostatic stabiliser |
A | HIS188 | electrostatic stabiliser |
A | TYR190 | proton shuttle (general acid/base) |