9E7U

Cryo-EM structure of NOT1:NOT8:PieF

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000175	molecular_function	3'-5'-RNA exonuclease activity
C	0000288	biological_process	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
C	0000289	biological_process	nuclear-transcribed mRNA poly(A) tail shortening
C	0000794	cellular_component	condensed nuclear chromosome
C	0000932	cellular_component	P-body
C	0003723	molecular_function	RNA binding
C	0004518	molecular_function	nuclease activity
C	0004527	molecular_function	exonuclease activity
C	0004535	molecular_function	poly(A)-specific ribonuclease activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005940	cellular_component	septin ring
C	0006351	biological_process	DNA-templated transcription
C	0006417	biological_process	regulation of translation
C	0008284	biological_process	positive regulation of cell population proliferation
C	0016787	molecular_function	hydrolase activity
C	0016925	biological_process	protein sumoylation
C	0030014	cellular_component	CCR4-NOT complex
C	0030015	cellular_component	CCR4-NOT core complex
C	0031047	biological_process	regulatory ncRNA-mediated gene silencing
C	0031386	molecular_function	protein tag activity
C	0035279	biological_process	miRNA-mediated gene silencing by mRNA destabilization
C	0042802	molecular_function	identical protein binding
C	0044389	molecular_function	ubiquitin-like protein ligase binding
C	0046872	molecular_function	metal ion binding
C	0061014	biological_process	positive regulation of mRNA catabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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