9E2T
Structure of a de novo designed interleukin-21 mimetic complex with IL-21R and IL-2Rg
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004896 | molecular_function | cytokine receptor activity |
| B | 0016020 | cellular_component | membrane |
| C | 0004896 | molecular_function | cytokine receptor activity |
| C | 0016020 | cellular_component | membrane |
| E | 0004896 | molecular_function | cytokine receptor activity |
| E | 0016020 | cellular_component | membrane |
| F | 0004896 | molecular_function | cytokine receptor activity |
| F | 0016020 | cellular_component | membrane |
| H | 0004896 | molecular_function | cytokine receptor activity |
| H | 0016020 | cellular_component | membrane |
| J | 0004896 | molecular_function | cytokine receptor activity |
| J | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS01355 |
| Number of Residues | 34 |
| Details | HEMATOPO_REC_S_F1 Short hematopoietin receptor family 1 signature. FrkdssyelqVRagpmpgssyqgt........WSeWSdpviF |
| Chain | Residue | Details |
| B | PHE171-PHE204 | |
| C | VAL213-TRP246 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Motif: {"description":"WSXWS motif"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22235133","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"C-linked (Man) tryptophan","evidences":[{"source":"PubMed","id":"22235133","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 291 |
| Details | Domain: {"description":"Fibronectin type-III 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 327 |
| Details | Domain: {"description":"Fibronectin type-III 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16293754","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16477002","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
