9DZO

Structure of ALAS bound to succinyl-CoA from S. cerevisiae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003870	molecular_function	5-aminolevulinate synthase activity
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0006782	biological_process	protoporphyrinogen IX biosynthetic process
A	0006783	biological_process	heme biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	1902117	biological_process	positive regulation of organelle assembly
B	0003870	molecular_function	5-aminolevulinate synthase activity
B	0005739	cellular_component	mitochondrion
B	0005759	cellular_component	mitochondrial matrix
B	0006782	biological_process	protoporphyrinogen IX biosynthetic process
B	0006783	biological_process	heme biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	1902117	biological_process	positive regulation of organelle assembly
C	0003870	molecular_function	5-aminolevulinate synthase activity
C	0005739	cellular_component	mitochondrion
C	0005759	cellular_component	mitochondrial matrix
C	0006782	biological_process	protoporphyrinogen IX biosynthetic process
C	0006783	biological_process	heme biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	1902117	biological_process	positive regulation of organelle assembly
D	0003870	molecular_function	5-aminolevulinate synthase activity
D	0005739	cellular_component	mitochondrion
D	0005759	cellular_component	mitochondrial matrix
D	0006782	biological_process	protoporphyrinogen IX biosynthetic process
D	0006783	biological_process	heme biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	1902117	biological_process	positive regulation of organelle assembly
E	0003870	molecular_function	5-aminolevulinate synthase activity
E	0005739	cellular_component	mitochondrion
E	0005759	cellular_component	mitochondrial matrix
E	0006782	biological_process	protoporphyrinogen IX biosynthetic process
E	0006783	biological_process	heme biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016746	molecular_function	acyltransferase activity
E	1902117	biological_process	positive regulation of organelle assembly
F	0003870	molecular_function	5-aminolevulinate synthase activity
F	0005739	cellular_component	mitochondrion
F	0005759	cellular_component	mitochondrial matrix
F	0006782	biological_process	protoporphyrinogen IX biosynthetic process
F	0006783	biological_process	heme biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016746	molecular_function	acyltransferase activity
F	1902117	biological_process	positive regulation of organelle assembly

Functional Information from PROSITE/UniProt

site_id	PS00599
Number of Residues	10
Details	AA_TRANSFER_CLASS_2 Aminotransferases class-II pyridoxal-phosphate attachment site. TLGKSFGSVG

Chain	Residue	Details
C	THR334-GLY343
F	THR334-GLY343

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"P18079","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P18079","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	18
Details	Binding site: {"description":"in other chain","evidences":[{"source":"UniProtKB","id":"P18079","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	6
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"UniProtKB","id":"P18079","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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