9DVT

Cryo-EM structure of RpaA bound to PkaiBC DNA and the CTD of the alpha subunit of RNAP from the cyanobacterium Synechococcus elongatus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed RNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006351	biological_process	DNA-templated transcription
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034062	molecular_function	5'-3' RNA polymerase activity
G	0003677	molecular_function	DNA binding
G	0005737	cellular_component	cytoplasm
G	0006351	biological_process	DNA-templated transcription
G	0006352	biological_process	DNA-templated transcription initiation
G	0006355	biological_process	regulation of DNA-templated transcription
G	0010468	biological_process	regulation of gene expression
G	0016987	molecular_function	sigma factor activity
G	2000142	biological_process	regulation of DNA-templated transcription initiation
R	0000156	molecular_function	phosphorelay response regulator activity
R	0000160	biological_process	phosphorelay signal transduction system
R	0000976	molecular_function	transcription cis-regulatory region binding
R	0003677	molecular_function	DNA binding
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0006351	biological_process	DNA-templated transcription
R	0006355	biological_process	regulation of DNA-templated transcription
R	0007623	biological_process	circadian rhythm
R	0032993	cellular_component	protein-DNA complex
R	0048511	biological_process	rhythmic process
R	0051301	biological_process	cell division
R	0097167	biological_process	circadian regulation of translation
S	0000156	molecular_function	phosphorelay response regulator activity
S	0000160	biological_process	phosphorelay signal transduction system
S	0000976	molecular_function	transcription cis-regulatory region binding
S	0003677	molecular_function	DNA binding
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006351	biological_process	DNA-templated transcription
S	0006355	biological_process	regulation of DNA-templated transcription
S	0007623	biological_process	circadian rhythm
S	0032993	cellular_component	protein-DNA complex
S	0048511	biological_process	rhythmic process
S	0051301	biological_process	cell division
S	0097167	biological_process	circadian regulation of translation

Functional Information from PROSITE/UniProt

site_id	PS00217
Number of Residues	26
Details	SUGAR_TRANSPORT_2 Sugar transport proteins signature 2. VeGFNaGAddyltkpFevEemlarvR

Chain	Residue	Details
R	VAL92-ARG117

---

site_id	PS00715
Number of Residues	14
Details	SIGMA70_1 Sigma-70 factors family signature 1. DLIQeGsLGLIrAA

Chain	Residue	Details
G	ASP191-ALA204

---

site_id	PS00716
Number of Residues	27
Details	SIGMA70_2 Sigma-70 factors family signature 2. TleEIGqlfnVTrerIrQIEakaLrkL

Chain	Residue	Details
G	THR359-LEU385

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	198
Details	DNA binding: {"description":"OmpR/PhoB-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01091","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"4-aspartylphosphate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00169","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24315105","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	19
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"HAMAP-Rule","id":"MF_00963","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	53
Details	Region: {"description":"Sigma-70 factor domain-4","evidences":[{"source":"HAMAP-Rule","id":"MF_00963","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---