9DJW

X-ray crystal structure of TNFa-VNAR D1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0042605	molecular_function	peptide antigen binding
1	0042605	molecular_function	peptide antigen binding
2	0005164	molecular_function	tumor necrosis factor receptor binding
2	0006955	biological_process	immune response
2	0016020	cellular_component	membrane
3	0005164	molecular_function	tumor necrosis factor receptor binding
3	0006955	biological_process	immune response
3	0016020	cellular_component	membrane
4	0005164	molecular_function	tumor necrosis factor receptor binding
4	0006955	biological_process	immune response
4	0016020	cellular_component	membrane
5	0042605	molecular_function	peptide antigen binding
6	0042605	molecular_function	peptide antigen binding
7	0042605	molecular_function	peptide antigen binding
a	0005164	molecular_function	tumor necrosis factor receptor binding
a	0006955	biological_process	immune response
a	0016020	cellular_component	membrane
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane
b	0042605	molecular_function	peptide antigen binding
B	0005164	molecular_function	tumor necrosis factor receptor binding
B	0006955	biological_process	immune response
B	0016020	cellular_component	membrane
c	0042605	molecular_function	peptide antigen binding
C	0005164	molecular_function	tumor necrosis factor receptor binding
C	0006955	biological_process	immune response
C	0016020	cellular_component	membrane
d	0042605	molecular_function	peptide antigen binding
D	0042605	molecular_function	peptide antigen binding
e	0005164	molecular_function	tumor necrosis factor receptor binding
e	0006955	biological_process	immune response
e	0016020	cellular_component	membrane
E	0042605	molecular_function	peptide antigen binding
f	0005164	molecular_function	tumor necrosis factor receptor binding
f	0006955	biological_process	immune response
f	0016020	cellular_component	membrane
F	0042605	molecular_function	peptide antigen binding
g	0005164	molecular_function	tumor necrosis factor receptor binding
g	0006955	biological_process	immune response
g	0016020	cellular_component	membrane
G	0005164	molecular_function	tumor necrosis factor receptor binding
G	0006955	biological_process	immune response
G	0016020	cellular_component	membrane
h	0042605	molecular_function	peptide antigen binding
H	0005164	molecular_function	tumor necrosis factor receptor binding
H	0006955	biological_process	immune response
H	0016020	cellular_component	membrane
i	0042605	molecular_function	peptide antigen binding
I	0005164	molecular_function	tumor necrosis factor receptor binding
I	0006955	biological_process	immune response
I	0016020	cellular_component	membrane
j	0042605	molecular_function	peptide antigen binding
J	0042605	molecular_function	peptide antigen binding
k	0005164	molecular_function	tumor necrosis factor receptor binding
k	0006955	biological_process	immune response
k	0016020	cellular_component	membrane
K	0042605	molecular_function	peptide antigen binding
l	0005164	molecular_function	tumor necrosis factor receptor binding
l	0006955	biological_process	immune response
l	0016020	cellular_component	membrane
L	0042605	molecular_function	peptide antigen binding
m	0005164	molecular_function	tumor necrosis factor receptor binding
m	0006955	biological_process	immune response
m	0016020	cellular_component	membrane
M	0005164	molecular_function	tumor necrosis factor receptor binding
M	0006955	biological_process	immune response
M	0016020	cellular_component	membrane
n	0042605	molecular_function	peptide antigen binding
N	0005164	molecular_function	tumor necrosis factor receptor binding
N	0006955	biological_process	immune response
N	0016020	cellular_component	membrane
o	0042605	molecular_function	peptide antigen binding
O	0005164	molecular_function	tumor necrosis factor receptor binding
O	0006955	biological_process	immune response
O	0016020	cellular_component	membrane
p	0042605	molecular_function	peptide antigen binding
P	0042605	molecular_function	peptide antigen binding
q	0005164	molecular_function	tumor necrosis factor receptor binding
q	0006955	biological_process	immune response
q	0016020	cellular_component	membrane
Q	0042605	molecular_function	peptide antigen binding
r	0005164	molecular_function	tumor necrosis factor receptor binding
r	0006955	biological_process	immune response
r	0016020	cellular_component	membrane
R	0042605	molecular_function	peptide antigen binding
s	0005164	molecular_function	tumor necrosis factor receptor binding
s	0006955	biological_process	immune response
s	0016020	cellular_component	membrane
S	0005164	molecular_function	tumor necrosis factor receptor binding
S	0006955	biological_process	immune response
S	0016020	cellular_component	membrane
t	0042605	molecular_function	peptide antigen binding
T	0005164	molecular_function	tumor necrosis factor receptor binding
T	0006955	biological_process	immune response
T	0016020	cellular_component	membrane
u	0042605	molecular_function	peptide antigen binding
U	0005164	molecular_function	tumor necrosis factor receptor binding
U	0006955	biological_process	immune response
U	0016020	cellular_component	membrane
v	0042605	molecular_function	peptide antigen binding
V	0042605	molecular_function	peptide antigen binding
w	0005164	molecular_function	tumor necrosis factor receptor binding
w	0006955	biological_process	immune response
w	0016020	cellular_component	membrane
W	0042605	molecular_function	peptide antigen binding
x	0005164	molecular_function	tumor necrosis factor receptor binding
x	0006955	biological_process	immune response
x	0016020	cellular_component	membrane
X	0042605	molecular_function	peptide antigen binding
y	0005164	molecular_function	tumor necrosis factor receptor binding
y	0006955	biological_process	immune response
y	0016020	cellular_component	membrane
Y	0005164	molecular_function	tumor necrosis factor receptor binding
Y	0006955	biological_process	immune response
Y	0016020	cellular_component	membrane
z	0042605	molecular_function	peptide antigen binding
Z	0005164	molecular_function	tumor necrosis factor receptor binding
Z	0006955	biological_process	immune response
Z	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00251
Number of Residues	17
Details	THD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LvVPsEGLYLIysQVlF

Chain	Residue	Details
S	LEU48-PHE64

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4205
Details	Domain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	9
Details	Glycosylation: {"description":"O-linked (GalNAc...) serine; in soluble form","evidences":[{"source":"PubMed","id":"8631363","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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