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9DJW

X-ray crystal structure of TNFa-VNAR D1 complex

Functional Information from GO Data
ChainGOidnamespacecontents
00002250biological_processadaptive immune response
00002376biological_processimmune system process
00042101cellular_componentT cell receptor complex
00042605molecular_functionpeptide antigen binding
10002250biological_processadaptive immune response
10002376biological_processimmune system process
10042101cellular_componentT cell receptor complex
10042605molecular_functionpeptide antigen binding
50002250biological_processadaptive immune response
50002376biological_processimmune system process
50042101cellular_componentT cell receptor complex
50042605molecular_functionpeptide antigen binding
60002250biological_processadaptive immune response
60002376biological_processimmune system process
60042101cellular_componentT cell receptor complex
60042605molecular_functionpeptide antigen binding
70002250biological_processadaptive immune response
70002376biological_processimmune system process
70042101cellular_componentT cell receptor complex
70042605molecular_functionpeptide antigen binding
D0002250biological_processadaptive immune response
D0002376biological_processimmune system process
D0042101cellular_componentT cell receptor complex
D0042605molecular_functionpeptide antigen binding
E0002250biological_processadaptive immune response
E0002376biological_processimmune system process
E0042101cellular_componentT cell receptor complex
E0042605molecular_functionpeptide antigen binding
F0002250biological_processadaptive immune response
F0002376biological_processimmune system process
F0042101cellular_componentT cell receptor complex
F0042605molecular_functionpeptide antigen binding
J0002250biological_processadaptive immune response
J0002376biological_processimmune system process
J0042101cellular_componentT cell receptor complex
J0042605molecular_functionpeptide antigen binding
K0002250biological_processadaptive immune response
K0002376biological_processimmune system process
K0042101cellular_componentT cell receptor complex
K0042605molecular_functionpeptide antigen binding
L0002250biological_processadaptive immune response
L0002376biological_processimmune system process
L0042101cellular_componentT cell receptor complex
L0042605molecular_functionpeptide antigen binding
P0002250biological_processadaptive immune response
P0002376biological_processimmune system process
P0042101cellular_componentT cell receptor complex
P0042605molecular_functionpeptide antigen binding
Q0002250biological_processadaptive immune response
Q0002376biological_processimmune system process
Q0042101cellular_componentT cell receptor complex
Q0042605molecular_functionpeptide antigen binding
R0002250biological_processadaptive immune response
R0002376biological_processimmune system process
R0042101cellular_componentT cell receptor complex
R0042605molecular_functionpeptide antigen binding
V0002250biological_processadaptive immune response
V0002376biological_processimmune system process
V0042101cellular_componentT cell receptor complex
V0042605molecular_functionpeptide antigen binding
W0002250biological_processadaptive immune response
W0002376biological_processimmune system process
W0042101cellular_componentT cell receptor complex
W0042605molecular_functionpeptide antigen binding
X0002250biological_processadaptive immune response
X0002376biological_processimmune system process
X0042101cellular_componentT cell receptor complex
X0042605molecular_functionpeptide antigen binding
b0002250biological_processadaptive immune response
b0002376biological_processimmune system process
b0042101cellular_componentT cell receptor complex
b0042605molecular_functionpeptide antigen binding
c0002250biological_processadaptive immune response
c0002376biological_processimmune system process
c0042101cellular_componentT cell receptor complex
c0042605molecular_functionpeptide antigen binding
d0002250biological_processadaptive immune response
d0002376biological_processimmune system process
d0042101cellular_componentT cell receptor complex
d0042605molecular_functionpeptide antigen binding
h0002250biological_processadaptive immune response
h0002376biological_processimmune system process
h0042101cellular_componentT cell receptor complex
h0042605molecular_functionpeptide antigen binding
i0002250biological_processadaptive immune response
i0002376biological_processimmune system process
i0042101cellular_componentT cell receptor complex
i0042605molecular_functionpeptide antigen binding
j0002250biological_processadaptive immune response
j0002376biological_processimmune system process
j0042101cellular_componentT cell receptor complex
j0042605molecular_functionpeptide antigen binding
n0002250biological_processadaptive immune response
n0002376biological_processimmune system process
n0042101cellular_componentT cell receptor complex
n0042605molecular_functionpeptide antigen binding
o0002250biological_processadaptive immune response
o0002376biological_processimmune system process
o0042101cellular_componentT cell receptor complex
o0042605molecular_functionpeptide antigen binding
p0002250biological_processadaptive immune response
p0002376biological_processimmune system process
p0042101cellular_componentT cell receptor complex
p0042605molecular_functionpeptide antigen binding
t0002250biological_processadaptive immune response
t0002376biological_processimmune system process
t0042101cellular_componentT cell receptor complex
t0042605molecular_functionpeptide antigen binding
u0002250biological_processadaptive immune response
u0002376biological_processimmune system process
u0042101cellular_componentT cell receptor complex
u0042605molecular_functionpeptide antigen binding
v0002250biological_processadaptive immune response
v0002376biological_processimmune system process
v0042101cellular_componentT cell receptor complex
v0042605molecular_functionpeptide antigen binding
z0002250biological_processadaptive immune response
z0002376biological_processimmune system process
z0042101cellular_componentT cell receptor complex
z0042605molecular_functionpeptide antigen binding
Functional Information from PROSITE/UniProt
site_idPS00251
Number of Residues17
DetailsTHD_1 Tumor necrosis factor (TNF) homology domain (THD) signature. LvVPsEGLYLIysQVlF
ChainResidueDetails
SLEU48-PHE64

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4205
DetailsDomain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues9
DetailsGlycosylation: {"description":"O-linked (GalNAc...) serine; in soluble form","evidences":[{"source":"PubMed","id":"8631363","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

246031

PDB entries from 2025-12-10

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