9CSD
The Ectodomains of SPRING and S1P with the inhibitor PF-429242
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00137 |
| Number of Residues | 11 |
| Details | SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGTfVAGvIAS |
| Chain | Residue | Details |
| A | HIS249-SER259 |
| site_id | PS00138 |
| Number of Residues | 11 |
| Details | SUBTILASE_SER Serine proteases, subtilase family, serine active site. GTSvAsPvVAG |
| Chain | Residue | Details |
| A | GLY412-GLY422 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 169 |
| Details | TOPO_DOM: Lumenal => ECO:0000305|PubMed:32111832 |
| Chain | Residue | Details |
| B | LYS36-ALA205 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:32111832 |
| Chain | Residue | Details |
| B | ASN67 | |
| A | HIS249 | |
| A | SER414 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:10644685 |
| Chain | Residue | Details |
| A | LEU186 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by FAM20C => ECO:0000269|PubMed:26091039 |
| Chain | Residue | Details |
| A | SER168 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 5 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN236 | |
| A | ASN305 | |
| A | ASN515 | |
| A | ASN728 | |
| A | ASN939 |
