9CP4
Cryo-EM structure of human GAT3 in complex with SNAP-5114, inward-open conformation
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH |
| Chain | Residue | Details |
| L | TYR193-HIS199 |
| site_id | PS00610 |
| Number of Residues | 15 |
| Details | NA_NEUROTRAN_SYMP_1 Sodium:neurotransmitter symporter family signature 1. WRFPYlcykNGGGaF |
| Chain | Residue | Details |
| A | TRP74-PHE88 |
| site_id | PS00754 |
| Number of Residues | 21 |
| Details | NA_NEUROTRAN_SYMP_2 Sodium:neurotransmitter symporter family signature 2. YLsnCFTteLPWatCghewNT |
| Chain | Residue | Details |
| A | TYR157-THR177 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 117 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-GLU58 | |
| A | THR572-PHE632 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE59-LEU79 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA87-LEU106 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY131-LEU151 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 73 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA152-ARG225 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| A | TRP226-TRP244 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 17 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL253-ILE270 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 17 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE306-TYR323 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE335-LEU356 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical; Name=8 => ECO:0000255 |
| Chain | Residue | Details |
| A | MET389-LEU408 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=9 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU438-THR456 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=10 => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY473-SER493 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical; Name=11 => ECO:0000255 |
| Chain | Residue | Details |
| A | TRP514-ILE533 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=12 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE553-ILE571 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P31647 |
| Chain | Residue | Details |
| A | SER21 |
| site_id | SWS_FT_FI16 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN187 | |
| A | ASN190 | |
| A | ASN198 |
