9CGV
SARS-CoV-2 nsp12 NiRAN domain bound to a covalent inhibitor SW090466-1
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00213 |
| Number of Residues | 12 |
| Details | LIPOCALIN Lipocalin signature. GTS..KFYGGWHNM |
| Chain | Residue | Details |
| A | GLY590-MET601 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by 3CL-PRO => ECO:0000250|UniProtKB:P0C6V3 |
| Chain | Residue | Details |
| C | GLN83 | |
| D | GLN198 | |
| A | ASP761 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33232691, ECO:0007744|PDB:7CYQ |
| Chain | Residue | Details |
| A | ASN209 | |
| A | ASP218 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01344, ECO:0000269|PubMed:32358203, ECO:0000269|PubMed:32526208, ECO:0000269|PubMed:33232691, ECO:0007744|PDB:7CYQ |
| Chain | Residue | Details |
| A | HIS295 | |
| A | CYS301 | |
| A | CYS306 | |
| A | CYS310 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01293, ECO:0000269|PubMed:32358203, ECO:0000269|PubMed:32526208, ECO:0000269|PubMed:33232691, ECO:0007744|PDB:7CYQ |
| Chain | Residue | Details |
| A | CYS487 | |
| A | HIS642 | |
| A | CYS646 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01293, ECO:0000269|PubMed:32358203, ECO:0000269|PubMed:32526208, ECO:0000269|PubMed:33232691 |
| Chain | Residue | Details |
| A | CYS645 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by 3CL-PRO => ECO:0000250|UniProtKB:P0C6V3 |
| Chain | Residue | Details |
| A | GLN0 | |
| A | GLN932 |
