9CDN

Respiratory supercomplex I+III2 open state

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0005743	cellular_component	mitochondrial inner membrane
0	0016020	cellular_component	membrane
0	0022904	biological_process	respiratory electron transport chain
0	0098803	cellular_component	respiratory chain complex
1	0005739	cellular_component	mitochondrion
1	0005743	cellular_component	mitochondrial inner membrane
1	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
1	0009060	biological_process	aerobic respiration
1	0016020	cellular_component	membrane
1	0022904	biological_process	respiratory electron transport chain
1	0045275	cellular_component	respiratory chain complex III
2	0005739	cellular_component	mitochondrion
2	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
2	0016020	cellular_component	membrane
2	0016491	molecular_function	oxidoreductase activity
2	0022904	biological_process	respiratory electron transport chain
2	0034551	biological_process	mitochondrial respiratory chain complex III assembly
2	0045275	cellular_component	respiratory chain complex III
2	0046872	molecular_function	metal ion binding
2	0051536	molecular_function	iron-sulfur cluster binding
2	0051537	molecular_function	2 iron, 2 sulfur cluster binding
2	1902600	biological_process	proton transmembrane transport
3	0005739	cellular_component	mitochondrion
3	0005743	cellular_component	mitochondrial inner membrane
3	0022904	biological_process	respiratory electron transport chain
3	0045275	cellular_component	respiratory chain complex III
4	0005739	cellular_component	mitochondrion
4	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
4	0016020	cellular_component	membrane
4	0016491	molecular_function	oxidoreductase activity
4	0022904	biological_process	respiratory electron transport chain
4	0034551	biological_process	mitochondrial respiratory chain complex III assembly
4	0045275	cellular_component	respiratory chain complex III
4	0046872	molecular_function	metal ion binding
4	0051536	molecular_function	iron-sulfur cluster binding
4	0051537	molecular_function	2 iron, 2 sulfur cluster binding
4	1902600	biological_process	proton transmembrane transport
5	0005743	cellular_component	mitochondrial inner membrane
5	0016020	cellular_component	membrane
5	0022904	biological_process	respiratory electron transport chain
5	0032991	cellular_component	protein-containing complex
6	0005739	cellular_component	mitochondrion
6	0005743	cellular_component	mitochondrial inner membrane
6	0022904	biological_process	respiratory electron transport chain
6	0045275	cellular_component	respiratory chain complex III
7	0005739	cellular_component	mitochondrion
7	0005743	cellular_component	mitochondrial inner membrane
7	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
7	0008121	molecular_function	quinol-cytochrome-c reductase activity
7	0016020	cellular_component	membrane
7	0022904	biological_process	respiratory electron transport chain
7	0045275	cellular_component	respiratory chain complex III
7	0046872	molecular_function	metal ion binding
7	1902600	biological_process	proton transmembrane transport
8	0005739	cellular_component	mitochondrion
8	0005743	cellular_component	mitochondrial inner membrane
8	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
8	0016020	cellular_component	membrane
8	0022904	biological_process	respiratory electron transport chain
8	0045275	cellular_component	respiratory chain complex III
8	0046872	molecular_function	metal ion binding
9	0005743	cellular_component	mitochondrial inner membrane
9	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
9	0016020	cellular_component	membrane
9	0022904	biological_process	respiratory electron transport chain
9	0045275	cellular_component	respiratory chain complex III
Aa	0005739	cellular_component	mitochondrion
Aa	0005743	cellular_component	mitochondrial inner membrane
Aa	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Aa	0016020	cellular_component	membrane
Aa	0021539	biological_process	subthalamus development
Aa	0021548	biological_process	pons development
Aa	0021680	biological_process	cerebellar Purkinje cell layer development
Aa	0021766	biological_process	hippocampus development
Aa	0021794	biological_process	thalamus development
Aa	0021854	biological_process	hypothalamus development
Aa	0021860	biological_process	pyramidal neuron development
Aa	0022904	biological_process	respiratory electron transport chain
Aa	0030901	biological_process	midbrain development
Aa	0045275	cellular_component	respiratory chain complex III
Ab	0005743	cellular_component	mitochondrial inner membrane
Ab	0016020	cellular_component	membrane
Ab	0022904	biological_process	respiratory electron transport chain
Ab	0098803	cellular_component	respiratory chain complex
Ac	0005739	cellular_component	mitochondrion
Ac	0005743	cellular_component	mitochondrial inner membrane
Ac	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Ac	0009060	biological_process	aerobic respiration
Ac	0016020	cellular_component	membrane
Ac	0022904	biological_process	respiratory electron transport chain
Ac	0045275	cellular_component	respiratory chain complex III
Ad	0005739	cellular_component	mitochondrion
Ad	0005743	cellular_component	mitochondrial inner membrane
Ad	0022904	biological_process	respiratory electron transport chain
Ad	0045275	cellular_component	respiratory chain complex III
Ae	0005739	cellular_component	mitochondrion
Ae	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Ae	0016020	cellular_component	membrane
Ae	0016491	molecular_function	oxidoreductase activity
Ae	0022904	biological_process	respiratory electron transport chain
Ae	0034551	biological_process	mitochondrial respiratory chain complex III assembly
Ae	0045275	cellular_component	respiratory chain complex III
Ae	0046872	molecular_function	metal ion binding
Ae	0051536	molecular_function	iron-sulfur cluster binding
Ae	0051537	molecular_function	2 iron, 2 sulfur cluster binding
Ae	1902600	biological_process	proton transmembrane transport
Af	0005739	cellular_component	mitochondrion
Af	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Af	0016020	cellular_component	membrane
Af	0016491	molecular_function	oxidoreductase activity
Af	0022904	biological_process	respiratory electron transport chain
Af	0034551	biological_process	mitochondrial respiratory chain complex III assembly
Af	0045275	cellular_component	respiratory chain complex III
Af	0046872	molecular_function	metal ion binding
Af	0051536	molecular_function	iron-sulfur cluster binding
Af	0051537	molecular_function	2 iron, 2 sulfur cluster binding
Af	1902600	biological_process	proton transmembrane transport
B	0000166	molecular_function	nucleotide binding
B	0005743	cellular_component	mitochondrial inner membrane
B	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0022904	biological_process	respiratory electron transport chain
B	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
B	0045271	cellular_component	respiratory chain complex I
B	0046872	molecular_function	metal ion binding
B	0051287	molecular_function	NAD binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	1902600	biological_process	proton transmembrane transport
C	0005743	cellular_component	mitochondrial inner membrane
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0045271	cellular_component	respiratory chain complex I
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	1902600	biological_process	proton transmembrane transport
D	0003954	molecular_function	NADH dehydrogenase activity
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
D	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
D	0016020	cellular_component	membrane
D	0031966	cellular_component	mitochondrial membrane
D	0032981	biological_process	mitochondrial respiratory chain complex I assembly
D	0045271	cellular_component	respiratory chain complex I
D	0072593	biological_process	reactive oxygen species metabolic process
D	1902600	biological_process	proton transmembrane transport
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
E	0007399	biological_process	nervous system development
E	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
E	0045271	cellular_component	respiratory chain complex I
E	0046872	molecular_function	metal ion binding
E	0048738	biological_process	cardiac muscle tissue development
E	0051536	molecular_function	iron-sulfur cluster binding
E	0051537	molecular_function	2 iron, 2 sulfur cluster binding
E	1902600	biological_process	proton transmembrane transport
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0022904	biological_process	respiratory electron transport chain
F	0045271	cellular_component	respiratory chain complex I
F	0046872	molecular_function	metal ion binding
G	0005743	cellular_component	mitochondrial inner membrane
G	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
G	0016491	molecular_function	oxidoreductase activity
G	0022904	biological_process	respiratory electron transport chain
G	0045271	cellular_component	respiratory chain complex I
G	0046872	molecular_function	metal ion binding
G	0051536	molecular_function	iron-sulfur cluster binding
G	0051537	molecular_function	2 iron, 2 sulfur cluster binding
G	0051539	molecular_function	4 iron, 4 sulfur cluster binding
G	1902600	biological_process	proton transmembrane transport
J	0005743	cellular_component	mitochondrial inner membrane
J	0016020	cellular_component	membrane
J	0022904	biological_process	respiratory electron transport chain
K	0005743	cellular_component	mitochondrial inner membrane
K	0022904	biological_process	respiratory electron transport chain
K	0045271	cellular_component	respiratory chain complex I
M	0005743	cellular_component	mitochondrial inner membrane
M	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
M	0022904	biological_process	respiratory electron transport chain
M	0045271	cellular_component	respiratory chain complex I
N	0005743	cellular_component	mitochondrial inner membrane
N	0022904	biological_process	respiratory electron transport chain
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0022904	biological_process	respiratory electron transport chain
P	0045271	cellular_component	respiratory chain complex I
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0022904	biological_process	respiratory electron transport chain
Q	0031966	cellular_component	mitochondrial membrane
Q	0032981	biological_process	mitochondrial respiratory chain complex I assembly
Q	0045271	cellular_component	respiratory chain complex I
T	0005743	cellular_component	mitochondrial inner membrane
T	0022904	biological_process	respiratory electron transport chain
T	0045271	cellular_component	respiratory chain complex I
U	0000166	molecular_function	nucleotide binding
U	0005525	molecular_function	GTP binding
U	0005759	cellular_component	mitochondrial matrix
U	0022904	biological_process	respiratory electron transport chain
U	0046872	molecular_function	metal ion binding
V	0005743	cellular_component	mitochondrial inner membrane
V	0045271	cellular_component	respiratory chain complex I
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0016020	cellular_component	membrane
W	0022904	biological_process	respiratory electron transport chain
W	0045271	cellular_component	respiratory chain complex I
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0022904	biological_process	respiratory electron transport chain
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0022904	biological_process	respiratory electron transport chain
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0022904	biological_process	respiratory electron transport chain
a	0045271	cellular_component	respiratory chain complex I
b	0005743	cellular_component	mitochondrial inner membrane
b	0022904	biological_process	respiratory electron transport chain
c	0005739	cellular_component	mitochondrion
c	0005743	cellular_component	mitochondrial inner membrane
c	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
c	0022904	biological_process	respiratory electron transport chain
c	0045271	cellular_component	respiratory chain complex I
f	0005743	cellular_component	mitochondrial inner membrane
f	0022904	biological_process	respiratory electron transport chain
g	0005737	cellular_component	cytoplasm
g	0005743	cellular_component	mitochondrial inner membrane
g	0022904	biological_process	respiratory electron transport chain
g	0032981	biological_process	mitochondrial respiratory chain complex I assembly
g	0045271	cellular_component	respiratory chain complex I
h	0005739	cellular_component	mitochondrion
h	0005743	cellular_component	mitochondrial inner membrane
h	0005758	cellular_component	mitochondrial intermembrane space
h	0022904	biological_process	respiratory electron transport chain
h	0032981	biological_process	mitochondrial respiratory chain complex I assembly
h	0045271	cellular_component	respiratory chain complex I
i	0005743	cellular_component	mitochondrial inner membrane
i	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
i	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
i	0022904	biological_process	respiratory electron transport chain
i	0032981	biological_process	mitochondrial respiratory chain complex I assembly
i	0045271	cellular_component	respiratory chain complex I
i	1902600	biological_process	proton transmembrane transport
j	0005743	cellular_component	mitochondrial inner membrane
j	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
j	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
j	0022904	biological_process	respiratory electron transport chain
j	0045271	cellular_component	respiratory chain complex I
j	1902600	biological_process	proton transmembrane transport
k	0005743	cellular_component	mitochondrial inner membrane
k	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
k	0022904	biological_process	respiratory electron transport chain
k	0045271	cellular_component	respiratory chain complex I
k	1902600	biological_process	proton transmembrane transport
l	0005743	cellular_component	mitochondrial inner membrane
l	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
l	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
l	0015990	biological_process	electron transport coupled proton transport
l	0022904	biological_process	respiratory electron transport chain
l	0032981	biological_process	mitochondrial respiratory chain complex I assembly
l	0045271	cellular_component	respiratory chain complex I
m	0005739	cellular_component	mitochondrion
m	0005743	cellular_component	mitochondrial inner membrane
m	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
m	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
m	0022904	biological_process	respiratory electron transport chain
m	0032981	biological_process	mitochondrial respiratory chain complex I assembly
m	0045271	cellular_component	respiratory chain complex I
m	1902600	biological_process	proton transmembrane transport
o	0005743	cellular_component	mitochondrial inner membrane
o	0022904	biological_process	respiratory electron transport chain
o	0045271	cellular_component	respiratory chain complex I
p	0005739	cellular_component	mitochondrion
p	0005743	cellular_component	mitochondrial inner membrane
p	0022904	biological_process	respiratory electron transport chain
p	0045271	cellular_component	respiratory chain complex I
q	0003954	molecular_function	NADH dehydrogenase activity
q	0005743	cellular_component	mitochondrial inner membrane
q	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
q	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
q	0009060	biological_process	aerobic respiration
q	0015990	biological_process	electron transport coupled proton transport
q	0022904	biological_process	respiratory electron transport chain
q	0032981	biological_process	mitochondrial respiratory chain complex I assembly
q	0045271	cellular_component	respiratory chain complex I
q	0048039	molecular_function	ubiquinone binding
r	0003954	molecular_function	NADH dehydrogenase activity
r	0005743	cellular_component	mitochondrial inner membrane
r	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
r	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
r	0009060	biological_process	aerobic respiration
r	0022904	biological_process	respiratory electron transport chain
r	0032981	biological_process	mitochondrial respiratory chain complex I assembly
r	0045271	cellular_component	respiratory chain complex I
r	1902600	biological_process	proton transmembrane transport
s	0005739	cellular_component	mitochondrion
s	0005758	cellular_component	mitochondrial intermembrane space
s	0022904	biological_process	respiratory electron transport chain
s	0045271	cellular_component	respiratory chain complex I
t	0005743	cellular_component	mitochondrial inner membrane
t	0005758	cellular_component	mitochondrial intermembrane space
t	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
t	0022904	biological_process	respiratory electron transport chain
t	0045271	cellular_component	respiratory chain complex I
t	1902600	biological_process	proton transmembrane transport
u	0005743	cellular_component	mitochondrial inner membrane
u	0016020	cellular_component	membrane
u	0022904	biological_process	respiratory electron transport chain
u	0032991	cellular_component	protein-containing complex
v	0005739	cellular_component	mitochondrion
v	0005743	cellular_component	mitochondrial inner membrane
v	0022904	biological_process	respiratory electron transport chain
v	0045275	cellular_component	respiratory chain complex III
w	0005739	cellular_component	mitochondrion
w	0005743	cellular_component	mitochondrial inner membrane
w	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
w	0008121	molecular_function	quinol-cytochrome-c reductase activity
w	0016020	cellular_component	membrane
w	0022904	biological_process	respiratory electron transport chain
w	0045275	cellular_component	respiratory chain complex III
w	0046872	molecular_function	metal ion binding
w	1902600	biological_process	proton transmembrane transport
x	0005739	cellular_component	mitochondrion
x	0005743	cellular_component	mitochondrial inner membrane
x	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
x	0016020	cellular_component	membrane
x	0022904	biological_process	respiratory electron transport chain
x	0045275	cellular_component	respiratory chain complex III
x	0046872	molecular_function	metal ion binding
y	0005743	cellular_component	mitochondrial inner membrane
y	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
y	0016020	cellular_component	membrane
y	0022904	biological_process	respiratory electron transport chain
y	0045275	cellular_component	respiratory chain complex III
z	0005739	cellular_component	mitochondrion
z	0005743	cellular_component	mitochondrial inner membrane
z	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
z	0016020	cellular_component	membrane
z	0021539	biological_process	subthalamus development
z	0021548	biological_process	pons development
z	0021680	biological_process	cerebellar Purkinje cell layer development
z	0021766	biological_process	hippocampus development
z	0021794	biological_process	thalamus development
z	0021854	biological_process	hypothalamus development
z	0021860	biological_process	pyramidal neuron development
z	0022904	biological_process	respiratory electron transport chain
z	0030901	biological_process	midbrain development
z	0045275	cellular_component	respiratory chain complex III

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM

Chain	Residue	Details
O	ASP107-MET122

---

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI

Chain	Residue	Details
O	ASP132-ILE144

---

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryedsnnlGtSHLLRLAsSlTT

Chain	Residue	Details
v	GLY68-THR91

---

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP

Chain	Residue	Details
H	CYS113-PRO124
H	CYS152-PRO163

---

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
C	LEU122-LYS133

---

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL

Chain	Residue	Details
D	GLU167-LEU188

---

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC

Chain	Residue	Details
G	PRO61-CYS78

---

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
G	CYS128-GLN140

---

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF

Chain	Residue	Details
G	ARG175-PHE185

---

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES

Chain	Residue	Details
B	GLY200-SER215

---

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
B	GLU377-GLY388

---

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpIaDALKLFtKE

Chain	Residue	Details
r	GLY44-GLU59

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G

Chain	Residue	Details
r	PRO197-GLY210

---

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP

Chain	Residue	Details
E	ASP166-PRO184

---

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
I	GLY152-PRO168

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI16
Number of Residues	1145
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---