9C6W
Crystal Structure of a single chain trimer composed of HLA-B*39:06 Y84C variant, beta-2microglobulin, and NRVMLPKAA peptide from NLRP2 (2 molecules/asymmetric unit)
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH |
| Chain | Residue | Details |
| A | TYR1079-HIS1085 | |
| A | TYR2257-HIS2263 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280 |
| Chain | Residue | Details |
| A | GLN1003 | |
| B | GLN1003 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269|PubMed:7918443 |
| Chain | Residue | Details |
| A | ILE1002 | |
| B | ILE1002 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443 |
| Chain | Residue | Details |
| A | LYS1020 | |
| B | LYS1059 | |
| B | LYS1092 | |
| B | LYS1095 | |
| A | LYS1042 | |
| A | LYS1049 | |
| A | LYS1059 | |
| A | LYS1092 | |
| A | LYS1095 | |
| B | LYS1020 | |
| B | LYS1042 | |
| B | LYS1049 |
