9BVT
RNA Pol II - High Mn(+2) concentration
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000428 | cellular_component | DNA-directed RNA polymerase complex |
| A | 0001054 | molecular_function | RNA polymerase I activity |
| A | 0001055 | molecular_function | RNA polymerase II activity |
| A | 0001056 | molecular_function | RNA polymerase III activity |
| A | 0001057 | molecular_function | RNA polymerase IV activity |
| A | 0001058 | molecular_function | RNA polymerase V activity |
| A | 0001059 | biological_process | transcription by RNA polymerase IV |
| A | 0001060 | biological_process | transcription by RNA polymerase V |
| A | 0001065 | molecular_function | mitochondrial single subunit type RNA polymerase activity |
| A | 0001066 | molecular_function | plastid single subunit type RNA polymerase activity |
| A | 0001172 | biological_process | RNA-templated transcription |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005665 | cellular_component | RNA polymerase II, core complex |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006360 | biological_process | transcription by RNA polymerase I |
| A | 0006366 | biological_process | transcription by RNA polymerase II |
| A | 0006367 | biological_process | transcription initiation at RNA polymerase II promoter |
| A | 0006368 | biological_process | transcription elongation by RNA polymerase II |
| A | 0006383 | biological_process | transcription by RNA polymerase III |
| A | 0006390 | biological_process | mitochondrial transcription |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0010494 | cellular_component | cytoplasmic stress granule |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0019985 | biological_process | translesion synthesis |
| A | 0034062 | molecular_function | 5'-3' RNA polymerase activity |
| A | 0042793 | biological_process | plastid transcription |
| A | 0046872 | molecular_function | metal ion binding |
| F | 0000428 | cellular_component | DNA-directed RNA polymerase complex |
| F | 0001054 | molecular_function | RNA polymerase I activity |
| F | 0001055 | molecular_function | RNA polymerase II activity |
| F | 0001056 | molecular_function | RNA polymerase III activity |
| F | 0001172 | biological_process | RNA-templated transcription |
| F | 0003968 | molecular_function | RNA-dependent RNA polymerase activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005634 | cellular_component | nucleus |
| F | 0005654 | cellular_component | nucleoplasm |
| F | 0005665 | cellular_component | RNA polymerase II, core complex |
| F | 0005666 | cellular_component | RNA polymerase III complex |
| F | 0005736 | cellular_component | RNA polymerase I complex |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006360 | biological_process | transcription by RNA polymerase I |
| F | 0006361 | biological_process | transcription initiation at RNA polymerase I promoter |
| F | 0006362 | biological_process | transcription elongation by RNA polymerase I |
| F | 0006363 | biological_process | termination of RNA polymerase I transcription |
| F | 0006366 | biological_process | transcription by RNA polymerase II |
| F | 0006367 | biological_process | transcription initiation at RNA polymerase II promoter |
| F | 0006368 | biological_process | transcription elongation by RNA polymerase II |
| F | 0006383 | biological_process | transcription by RNA polymerase III |
| F | 0006384 | biological_process | transcription initiation at RNA polymerase III promoter |
| F | 0006386 | biological_process | termination of RNA polymerase III transcription |
| F | 0042254 | biological_process | ribosome biogenesis |
| F | 0042790 | biological_process | nucleolar large rRNA transcription by RNA polymerase I |
| F | 0042797 | biological_process | tRNA transcription by RNA polymerase III |
Functional Information from PROSITE/UniProt
| site_id | PS00115 |
| Number of Residues | 7 |
| Details | RNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPA |
| Chain | Residue | Details |
| A | TYR1549-ALA1555 | |
| A | TYR1612-SER1618 | |
| A | TYR1619-SER1625 | |
| A | TYR1626-SER1632 | |
| A | TYR1633-SER1639 | |
| A | TYR1640-SER1646 | |
| A | TYR1647-SER1653 | |
| A | TYR1654-ALA1660 | |
| A | TYR1661-SER1667 | |
| A | TYR1668-SER1674 | |
| A | TYR1675-SER1681 | |
| A | TYR1556-SER1562 | |
| A | TYR1682-SER1688 | |
| A | TYR1689-ASN1695 | |
| A | TYR1696-SER1702 | |
| A | TYR1563-SER1569 | |
| A | TYR1570-SER1576 | |
| A | TYR1577-SER1583 | |
| A | TYR1584-SER1590 | |
| A | TYR1591-SER1597 | |
| A | TYR1598-SER1604 | |
| A | TYR1605-SER1611 |
| site_id | PS00446 |
| Number of Residues | 41 |
| Details | RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSLRRvmiaeiptlAidsVevetNtTvlaDEfIAhRLGLIP |
| Chain | Residue | Details |
| C | ASN31-PRO71 |
| site_id | PS00466 |
| Number of Residues | 36 |
| Details | ZF_TFIIS_1 Zinc finger TFIIS-type signature. CpkChsrenvffqSQQRRkDTSmvlffvCls...CshiF |
| Chain | Residue | Details |
| I | CYS75-PHE110 |
| site_id | PS01030 |
| Number of Residues | 27 |
| Details | RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCRDCNNMLypredkennrllfeCrtC |
| Chain | Residue | Details |
| I | PHE6-CYS32 |
| site_id | PS01110 |
| Number of Residues | 14 |
| Details | RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPKHirLssDE |
| Chain | Residue | Details |
| E | HIS147-GLU160 |
| site_id | PS01111 |
| Number of Residues | 15 |
| Details | RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARiLGtRAlQ |
| Chain | Residue | Details |
| F | THR86-GLN100 |
| site_id | PS01112 |
| Number of Residues | 10 |
| Details | RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IVPVrCFSCG |
| Chain | Residue | Details |
| J | ILE2-GLY11 |
| site_id | PS01154 |
| Number of Residues | 32 |
| Details | RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. FekEdHTLgNlIraeLlndrkVlfaaYkveHP |
| Chain | Residue | Details |
| K | PHE35-PRO66 |
| site_id | PS01166 |
| Number of Residues | 13 |
| Details | RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT |
| Chain | Residue | Details |
| B | GLY977-THR989 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956 |
| Chain | Residue | Details |
| F | SER24 | |
| A | ASP483 | |
| A | ASP485 | |
| A | CYS70 | |
| A | CYS77 | |
| A | HIS80 | |
| A | CYS107 | |
| A | CYS110 | |
| A | CYS148 | |
| A | CYS167 | |
| A | ASP481 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18407956 |
| Chain | Residue | Details |
| A | THR1471 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047 |
| Chain | Residue | Details |
| A | LYS695 | |
| A | LYS1350 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:32142654, ECO:0007744|PubMed:22106047 |
| Chain | Residue | Details |
| A | LYS1246 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 788 |
| Chain | Residue | Details |
| A | ASP481 | metal ligand |
| A | ASP483 | metal ligand |
| A | ASP485 | metal ligand |
| A | HIS1085 | proton acceptor, proton donor |
