9BRZ
V0-only V-ATPase and synaptophysin complex in mouse brain isolated synaptic vesicles
Functional Information from PROSITE/UniProt
| site_id | PS00604 |
| Number of Residues | 9 |
| Details | SYNAPTOP Synaptophysin / synaptoporin signature. LSVECaNKT |
| Chain | Residue | Details |
| s | LEU53-THR61 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 484 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| a | MET1-GLU388 | |
| j | MET1-TYR10 | |
| j | ALA77-GLN92 | |
| j | SER153-LYS155 | |
| k | MET1-TYR10 | |
| k | ALA77-GLN92 | |
| k | SER153-LYS155 | |
| l | MET1-TYR10 | |
| l | ALA77-GLN92 | |
| l | SER153-LYS155 | |
| m | MET1-TYR10 | |
| a | GLU427-SER441 | |
| m | ALA77-GLN92 | |
| m | SER153-LYS155 | |
| n | MET1-TYR10 | |
| n | ALA77-GLN92 | |
| n | SER153-LYS155 | |
| o | MET1-TYR10 | |
| o | ALA77-GLN92 | |
| o | SER153-LYS155 | |
| a | SER556-PHE573 | |
| a | ARG660-THR725 | |
| h | ALA77-GLN92 | |
| h | SER153-LYS155 | |
| i | MET1-TYR10 | |
| i | ALA77-GLN92 | |
| i | SER153-LYS155 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 183 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| a | ILE389-PHE407 | |
| i | ILE56-ILE76 | |
| i | LEU93-GLY114 | |
| i | ILE132-LEU152 | |
| j | SER11-GLY33 | |
| j | ILE56-ILE76 | |
| j | LEU93-GLY114 | |
| j | ILE132-LEU152 | |
| k | SER11-GLY33 | |
| k | ILE56-ILE76 | |
| k | LEU93-GLY114 | |
| a | PHE410-ARG426 | |
| k | ILE132-LEU152 | |
| l | SER11-GLY33 | |
| l | ILE56-ILE76 | |
| l | LEU93-GLY114 | |
| l | ILE132-LEU152 | |
| m | SER11-GLY33 | |
| m | ILE56-ILE76 | |
| m | LEU93-GLY114 | |
| m | ILE132-LEU152 | |
| n | SER11-GLY33 | |
| a | MET442-SER471 | |
| n | ILE56-ILE76 | |
| n | LEU93-GLY114 | |
| n | ILE132-LEU152 | |
| o | SER11-GLY33 | |
| o | ILE56-ILE76 | |
| o | LEU93-GLY114 | |
| o | ILE132-LEU152 | |
| a | PHE536-LEU555 | |
| a | ILE574-LYS594 | |
| a | LEU640-LEU659 | |
| a | ILE726-ALA750 | |
| a | GLY772-GLU810 | |
| i | SER11-GLY33 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 128 |
| Details | TOPO_DOM: Vacuolar => ECO:0000255 |
| Chain | Residue | Details |
| a | GLY408-ASP409 | |
| k | ASP115-MET131 | |
| l | THR34-SER55 | |
| l | ASP115-MET131 | |
| m | THR34-SER55 | |
| m | ASP115-MET131 | |
| n | THR34-SER55 | |
| n | ASP115-MET131 | |
| o | THR34-SER55 | |
| o | ASP115-MET131 | |
| a | LEU472-SER535 | |
| a | TRP595-PHE639 | |
| a | GLN751-ALA771 | |
| i | THR34-SER55 | |
| i | ASP115-MET131 | |
| j | THR34-SER55 | |
| j | ASP115-MET131 | |
| k | THR34-SER55 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21183079 |
| Chain | Residue | Details |
| a | THR250 | |
| p | SER576 | |
| i | GLU139 | |
| j | GLU139 | |
| k | GLU139 | |
| l | GLU139 | |
| m | GLU139 | |
| n | GLU139 | |
| o | GLU139 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q93050 |
| Chain | Residue | Details |
| a | THR360 | |
| c | ASN267 | |
| c | ASN290 | |
| c | ASN297 | |
| c | ASN344 | |
| c | ASN351 | |
| c | ASN399 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:18034455 |
| Chain | Residue | Details |
| a | TYR364 | |
| s | TYR296 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| s | ASN59 |
