9BPB

Tethered respiratory III2IV2 supercomplex from Saccharomyces cerevisiae

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0004129	molecular_function	cytochrome-c oxidase activity
a	0005515	molecular_function	protein binding
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0006119	biological_process	oxidative phosphorylation
a	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
a	0009060	biological_process	aerobic respiration
a	0016020	cellular_component	membrane
a	0020037	molecular_function	heme binding
a	0022904	biological_process	respiratory electron transport chain
a	0031966	cellular_component	mitochondrial membrane
a	0045277	cellular_component	respiratory chain complex IV
a	0045333	biological_process	cellular respiration
a	0046872	molecular_function	metal ion binding
a	1902600	biological_process	proton transmembrane transport
A	0004222	molecular_function	metalloendopeptidase activity
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
A	0006627	biological_process	protein processing involved in protein targeting to mitochondrion
A	0008121	molecular_function	quinol-cytochrome-c reductase activity
A	0009060	biological_process	aerobic respiration
A	0017087	cellular_component	mitochondrial processing peptidase complex
A	0022904	biological_process	respiratory electron transport chain
A	0045275	cellular_component	respiratory chain complex III
A	0045333	biological_process	cellular respiration
A	0046872	molecular_function	metal ion binding
A	1902600	biological_process	proton transmembrane transport
b	0004129	molecular_function	cytochrome-c oxidase activity
b	0005507	molecular_function	copper ion binding
b	0005515	molecular_function	protein binding
b	0005739	cellular_component	mitochondrion
b	0005743	cellular_component	mitochondrial inner membrane
b	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
b	0009060	biological_process	aerobic respiration
b	0016020	cellular_component	membrane
b	0016491	molecular_function	oxidoreductase activity
b	0022900	biological_process	electron transport chain
b	0022904	biological_process	respiratory electron transport chain
b	0031966	cellular_component	mitochondrial membrane
b	0042773	biological_process	ATP synthesis coupled electron transport
b	0045277	cellular_component	respiratory chain complex IV
b	0046872	molecular_function	metal ion binding
b	1902600	biological_process	proton transmembrane transport
B	0004222	molecular_function	metalloendopeptidase activity
B	0005515	molecular_function	protein binding
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
B	0006508	biological_process	proteolysis
B	0008121	molecular_function	quinol-cytochrome-c reductase activity
B	0009060	biological_process	aerobic respiration
B	0016020	cellular_component	membrane
B	0022904	biological_process	respiratory electron transport chain
B	0030061	cellular_component	mitochondrial crista
B	0045275	cellular_component	respiratory chain complex III
B	0045333	biological_process	cellular respiration
B	0046872	molecular_function	metal ion binding
B	1902600	biological_process	proton transmembrane transport
c	0004129	molecular_function	cytochrome-c oxidase activity
c	0005739	cellular_component	mitochondrion
c	0005743	cellular_component	mitochondrial inner membrane
c	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
c	0009055	molecular_function	electron transfer activity
c	0009060	biological_process	aerobic respiration
c	0016020	cellular_component	membrane
c	0019646	biological_process	aerobic electron transport chain
c	0022904	biological_process	respiratory electron transport chain
c	0031966	cellular_component	mitochondrial membrane
c	0045277	cellular_component	respiratory chain complex IV
c	0045333	biological_process	cellular respiration
c	0048039	molecular_function	ubiquinone binding
c	1902600	biological_process	proton transmembrane transport
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
C	0008121	molecular_function	quinol-cytochrome-c reductase activity
C	0009055	molecular_function	electron transfer activity
C	0009060	biological_process	aerobic respiration
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0022904	biological_process	respiratory electron transport chain
C	0045275	cellular_component	respiratory chain complex III
C	0045333	biological_process	cellular respiration
C	0046872	molecular_function	metal ion binding
C	1902600	biological_process	proton transmembrane transport
d	0004129	molecular_function	cytochrome-c oxidase activity
d	0005515	molecular_function	protein binding
d	0005739	cellular_component	mitochondrion
d	0005740	cellular_component	mitochondrial envelope
d	0005743	cellular_component	mitochondrial inner membrane
d	0005758	cellular_component	mitochondrial intermembrane space
d	0006119	biological_process	oxidative phosphorylation
d	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
d	0008270	molecular_function	zinc ion binding
d	0016491	molecular_function	oxidoreductase activity
d	0033617	biological_process	mitochondrial respiratory chain complex IV assembly
d	0045277	cellular_component	respiratory chain complex IV
d	0046872	molecular_function	metal ion binding
d	1902600	biological_process	proton transmembrane transport
d	1990145	biological_process	maintenance of translational fidelity
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0005758	cellular_component	mitochondrial intermembrane space
D	0005829	cellular_component	cytosol
D	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
D	0008121	molecular_function	quinol-cytochrome-c reductase activity
D	0009055	molecular_function	electron transfer activity
D	0016020	cellular_component	membrane
D	0020037	molecular_function	heme binding
D	0022904	biological_process	respiratory electron transport chain
D	0045275	cellular_component	respiratory chain complex III
D	0045333	biological_process	cellular respiration
D	0046872	molecular_function	metal ion binding
D	1902600	biological_process	proton transmembrane transport
e	0004129	molecular_function	cytochrome-c oxidase activity
e	0005515	molecular_function	protein binding
e	0005739	cellular_component	mitochondrion
e	0005743	cellular_component	mitochondrial inner membrane
e	0005758	cellular_component	mitochondrial intermembrane space
e	0006119	biological_process	oxidative phosphorylation
e	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
e	0016491	molecular_function	oxidoreductase activity
e	0045277	cellular_component	respiratory chain complex IV
e	1902600	biological_process	proton transmembrane transport
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
E	0008121	molecular_function	quinol-cytochrome-c reductase activity
E	0009060	biological_process	aerobic respiration
E	0016020	cellular_component	membrane
E	0016491	molecular_function	oxidoreductase activity
E	0022904	biological_process	respiratory electron transport chain
E	0045275	cellular_component	respiratory chain complex III
E	0045333	biological_process	cellular respiration
E	0046872	molecular_function	metal ion binding
E	0051536	molecular_function	iron-sulfur cluster binding
E	0051537	molecular_function	2 iron, 2 sulfur cluster binding
E	1902600	biological_process	proton transmembrane transport
f	0004129	molecular_function	cytochrome-c oxidase activity
f	0005739	cellular_component	mitochondrion
f	0005743	cellular_component	mitochondrial inner membrane
f	0006119	biological_process	oxidative phosphorylation
f	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
f	0016491	molecular_function	oxidoreductase activity
f	0045277	cellular_component	respiratory chain complex IV
f	0046872	molecular_function	metal ion binding
f	1902600	biological_process	proton transmembrane transport
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005758	cellular_component	mitochondrial intermembrane space
F	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
F	0008121	molecular_function	quinol-cytochrome-c reductase activity
F	0009060	biological_process	aerobic respiration
F	0016020	cellular_component	membrane
F	0022904	biological_process	respiratory electron transport chain
F	0034399	cellular_component	nuclear periphery
F	0045275	cellular_component	respiratory chain complex III
F	0045333	biological_process	cellular respiration
F	1902600	biological_process	proton transmembrane transport
g	0004129	molecular_function	cytochrome-c oxidase activity
g	0005739	cellular_component	mitochondrion
g	0005743	cellular_component	mitochondrial inner membrane
g	0006119	biological_process	oxidative phosphorylation
g	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
g	0016491	molecular_function	oxidoreductase activity
g	0031966	cellular_component	mitochondrial membrane
g	0045277	cellular_component	respiratory chain complex IV
g	0045333	biological_process	cellular respiration
g	1902600	biological_process	proton transmembrane transport
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
G	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
G	0008121	molecular_function	quinol-cytochrome-c reductase activity
G	0009060	biological_process	aerobic respiration
G	0016020	cellular_component	membrane
G	0022904	biological_process	respiratory electron transport chain
G	0034551	biological_process	mitochondrial respiratory chain complex III assembly
G	0045275	cellular_component	respiratory chain complex III
G	0045277	cellular_component	respiratory chain complex IV
G	0045333	biological_process	cellular respiration
G	0099617	cellular_component	matrix side of mitochondrial inner membrane
G	1902600	biological_process	proton transmembrane transport
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
H	0008121	molecular_function	quinol-cytochrome-c reductase activity
H	0009060	biological_process	aerobic respiration
H	0016020	cellular_component	membrane
H	0022904	biological_process	respiratory electron transport chain
H	0045275	cellular_component	respiratory chain complex III
H	0045333	biological_process	cellular respiration
H	1902600	biological_process	proton transmembrane transport
i	0004129	molecular_function	cytochrome-c oxidase activity
i	0005739	cellular_component	mitochondrion
i	0005743	cellular_component	mitochondrial inner membrane
i	0006119	biological_process	oxidative phosphorylation
i	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
i	0016491	molecular_function	oxidoreductase activity
i	0045277	cellular_component	respiratory chain complex IV
i	1902600	biological_process	proton transmembrane transport
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
I	0008121	molecular_function	quinol-cytochrome-c reductase activity
I	0009060	biological_process	aerobic respiration
I	0016020	cellular_component	membrane
I	0022904	biological_process	respiratory electron transport chain
I	0034551	biological_process	mitochondrial respiratory chain complex III assembly
I	0045275	cellular_component	respiratory chain complex III
I	0045333	biological_process	cellular respiration
I	1902600	biological_process	proton transmembrane transport
j	0004129	molecular_function	cytochrome-c oxidase activity
j	0005739	cellular_component	mitochondrion
j	0005743	cellular_component	mitochondrial inner membrane
j	0005758	cellular_component	mitochondrial intermembrane space
j	0006119	biological_process	oxidative phosphorylation
j	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
j	0016491	molecular_function	oxidoreductase activity
j	0031966	cellular_component	mitochondrial membrane
j	0033617	biological_process	mitochondrial respiratory chain complex IV assembly
j	0045277	cellular_component	respiratory chain complex IV
j	0045333	biological_process	cellular respiration
j	1902600	biological_process	proton transmembrane transport
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
J	0008121	molecular_function	quinol-cytochrome-c reductase activity
J	0009060	biological_process	aerobic respiration
J	0022904	biological_process	respiratory electron transport chain
J	0045275	cellular_component	respiratory chain complex III
J	0045333	biological_process	cellular respiration
J	1902600	biological_process	proton transmembrane transport
k	0004129	molecular_function	cytochrome-c oxidase activity
k	0005739	cellular_component	mitochondrion
k	0005743	cellular_component	mitochondrial inner membrane
k	0006119	biological_process	oxidative phosphorylation
k	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
k	0009060	biological_process	aerobic respiration
k	0016491	molecular_function	oxidoreductase activity
k	0030234	molecular_function	enzyme regulator activity
k	0045277	cellular_component	respiratory chain complex IV
k	0097250	biological_process	mitochondrial respirasome assembly
k	1902600	biological_process	proton transmembrane transport
K	0004222	molecular_function	metalloendopeptidase activity
K	0005515	molecular_function	protein binding
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
K	0006627	biological_process	protein processing involved in protein targeting to mitochondrion
K	0008121	molecular_function	quinol-cytochrome-c reductase activity
K	0009060	biological_process	aerobic respiration
K	0017087	cellular_component	mitochondrial processing peptidase complex
K	0022904	biological_process	respiratory electron transport chain
K	0045275	cellular_component	respiratory chain complex III
K	0045333	biological_process	cellular respiration
K	0046872	molecular_function	metal ion binding
K	1902600	biological_process	proton transmembrane transport
l	0003674	molecular_function	molecular_function
l	0005739	cellular_component	mitochondrion
l	0005743	cellular_component	mitochondrial inner membrane
l	0008150	biological_process	biological_process
l	0045277	cellular_component	respiratory chain complex IV
l	0098803	cellular_component	respiratory chain complex
L	0004222	molecular_function	metalloendopeptidase activity
L	0005515	molecular_function	protein binding
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
L	0006508	biological_process	proteolysis
L	0008121	molecular_function	quinol-cytochrome-c reductase activity
L	0009060	biological_process	aerobic respiration
L	0016020	cellular_component	membrane
L	0022904	biological_process	respiratory electron transport chain
L	0030061	cellular_component	mitochondrial crista
L	0045275	cellular_component	respiratory chain complex III
L	0045333	biological_process	cellular respiration
L	0046872	molecular_function	metal ion binding
L	1902600	biological_process	proton transmembrane transport
m	0004129	molecular_function	cytochrome-c oxidase activity
m	0005515	molecular_function	protein binding
m	0005739	cellular_component	mitochondrion
m	0005743	cellular_component	mitochondrial inner membrane
m	0006119	biological_process	oxidative phosphorylation
m	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
m	0009060	biological_process	aerobic respiration
m	0016020	cellular_component	membrane
m	0020037	molecular_function	heme binding
m	0022904	biological_process	respiratory electron transport chain
m	0031966	cellular_component	mitochondrial membrane
m	0045277	cellular_component	respiratory chain complex IV
m	0045333	biological_process	cellular respiration
m	0046872	molecular_function	metal ion binding
m	1902600	biological_process	proton transmembrane transport
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
M	0008121	molecular_function	quinol-cytochrome-c reductase activity
M	0009055	molecular_function	electron transfer activity
M	0009060	biological_process	aerobic respiration
M	0016020	cellular_component	membrane
M	0016491	molecular_function	oxidoreductase activity
M	0022904	biological_process	respiratory electron transport chain
M	0045275	cellular_component	respiratory chain complex III
M	0045333	biological_process	cellular respiration
M	0046872	molecular_function	metal ion binding
M	1902600	biological_process	proton transmembrane transport
n	0004129	molecular_function	cytochrome-c oxidase activity
n	0005507	molecular_function	copper ion binding
n	0005515	molecular_function	protein binding
n	0005739	cellular_component	mitochondrion
n	0005743	cellular_component	mitochondrial inner membrane
n	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
n	0009060	biological_process	aerobic respiration
n	0016020	cellular_component	membrane
n	0016491	molecular_function	oxidoreductase activity
n	0022900	biological_process	electron transport chain
n	0022904	biological_process	respiratory electron transport chain
n	0031966	cellular_component	mitochondrial membrane
n	0042773	biological_process	ATP synthesis coupled electron transport
n	0045277	cellular_component	respiratory chain complex IV
n	0046872	molecular_function	metal ion binding
n	1902600	biological_process	proton transmembrane transport
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0005758	cellular_component	mitochondrial intermembrane space
N	0005829	cellular_component	cytosol
N	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
N	0008121	molecular_function	quinol-cytochrome-c reductase activity
N	0009055	molecular_function	electron transfer activity
N	0016020	cellular_component	membrane
N	0020037	molecular_function	heme binding
N	0022904	biological_process	respiratory electron transport chain
N	0045275	cellular_component	respiratory chain complex III
N	0045333	biological_process	cellular respiration
N	0046872	molecular_function	metal ion binding
N	1902600	biological_process	proton transmembrane transport
o	0004129	molecular_function	cytochrome-c oxidase activity
o	0005739	cellular_component	mitochondrion
o	0005743	cellular_component	mitochondrial inner membrane
o	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
o	0009055	molecular_function	electron transfer activity
o	0009060	biological_process	aerobic respiration
o	0016020	cellular_component	membrane
o	0019646	biological_process	aerobic electron transport chain
o	0022904	biological_process	respiratory electron transport chain
o	0031966	cellular_component	mitochondrial membrane
o	0045277	cellular_component	respiratory chain complex IV
o	0045333	biological_process	cellular respiration
o	0048039	molecular_function	ubiquinone binding
o	1902600	biological_process	proton transmembrane transport
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
O	0008121	molecular_function	quinol-cytochrome-c reductase activity
O	0009060	biological_process	aerobic respiration
O	0016020	cellular_component	membrane
O	0016491	molecular_function	oxidoreductase activity
O	0022904	biological_process	respiratory electron transport chain
O	0045275	cellular_component	respiratory chain complex III
O	0045333	biological_process	cellular respiration
O	0046872	molecular_function	metal ion binding
O	0051536	molecular_function	iron-sulfur cluster binding
O	0051537	molecular_function	2 iron, 2 sulfur cluster binding
O	1902600	biological_process	proton transmembrane transport
p	0004129	molecular_function	cytochrome-c oxidase activity
p	0005515	molecular_function	protein binding
p	0005739	cellular_component	mitochondrion
p	0005740	cellular_component	mitochondrial envelope
p	0005743	cellular_component	mitochondrial inner membrane
p	0005758	cellular_component	mitochondrial intermembrane space
p	0006119	biological_process	oxidative phosphorylation
p	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
p	0008270	molecular_function	zinc ion binding
p	0016491	molecular_function	oxidoreductase activity
p	0033617	biological_process	mitochondrial respiratory chain complex IV assembly
p	0045277	cellular_component	respiratory chain complex IV
p	0046872	molecular_function	metal ion binding
p	1902600	biological_process	proton transmembrane transport
p	1990145	biological_process	maintenance of translational fidelity
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0005758	cellular_component	mitochondrial intermembrane space
P	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
P	0008121	molecular_function	quinol-cytochrome-c reductase activity
P	0009060	biological_process	aerobic respiration
P	0016020	cellular_component	membrane
P	0022904	biological_process	respiratory electron transport chain
P	0034399	cellular_component	nuclear periphery
P	0045275	cellular_component	respiratory chain complex III
P	0045333	biological_process	cellular respiration
P	1902600	biological_process	proton transmembrane transport
q	0004129	molecular_function	cytochrome-c oxidase activity
q	0005515	molecular_function	protein binding
q	0005739	cellular_component	mitochondrion
q	0005743	cellular_component	mitochondrial inner membrane
q	0005758	cellular_component	mitochondrial intermembrane space
q	0006119	biological_process	oxidative phosphorylation
q	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
q	0016491	molecular_function	oxidoreductase activity
q	0045277	cellular_component	respiratory chain complex IV
q	1902600	biological_process	proton transmembrane transport
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Q	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
Q	0008121	molecular_function	quinol-cytochrome-c reductase activity
Q	0009060	biological_process	aerobic respiration
Q	0016020	cellular_component	membrane
Q	0022904	biological_process	respiratory electron transport chain
Q	0034551	biological_process	mitochondrial respiratory chain complex III assembly
Q	0045275	cellular_component	respiratory chain complex III
Q	0045277	cellular_component	respiratory chain complex IV
Q	0045333	biological_process	cellular respiration
Q	0099617	cellular_component	matrix side of mitochondrial inner membrane
Q	1902600	biological_process	proton transmembrane transport
r	0004129	molecular_function	cytochrome-c oxidase activity
r	0005739	cellular_component	mitochondrion
r	0005743	cellular_component	mitochondrial inner membrane
r	0006119	biological_process	oxidative phosphorylation
r	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
r	0016491	molecular_function	oxidoreductase activity
r	0045277	cellular_component	respiratory chain complex IV
r	0046872	molecular_function	metal ion binding
r	1902600	biological_process	proton transmembrane transport
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
R	0008121	molecular_function	quinol-cytochrome-c reductase activity
R	0009060	biological_process	aerobic respiration
R	0016020	cellular_component	membrane
R	0022904	biological_process	respiratory electron transport chain
R	0045275	cellular_component	respiratory chain complex III
R	0045333	biological_process	cellular respiration
R	1902600	biological_process	proton transmembrane transport
s	0004129	molecular_function	cytochrome-c oxidase activity
s	0005739	cellular_component	mitochondrion
s	0005743	cellular_component	mitochondrial inner membrane
s	0006119	biological_process	oxidative phosphorylation
s	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
s	0016491	molecular_function	oxidoreductase activity
s	0031966	cellular_component	mitochondrial membrane
s	0045277	cellular_component	respiratory chain complex IV
s	0045333	biological_process	cellular respiration
s	1902600	biological_process	proton transmembrane transport
S	0005739	cellular_component	mitochondrion
S	0005743	cellular_component	mitochondrial inner membrane
S	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
S	0008121	molecular_function	quinol-cytochrome-c reductase activity
S	0009060	biological_process	aerobic respiration
S	0016020	cellular_component	membrane
S	0022904	biological_process	respiratory electron transport chain
S	0034551	biological_process	mitochondrial respiratory chain complex III assembly
S	0045275	cellular_component	respiratory chain complex III
S	0045333	biological_process	cellular respiration
S	1902600	biological_process	proton transmembrane transport
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
T	0008121	molecular_function	quinol-cytochrome-c reductase activity
T	0009060	biological_process	aerobic respiration
T	0022904	biological_process	respiratory electron transport chain
T	0045275	cellular_component	respiratory chain complex III
T	0045333	biological_process	cellular respiration
T	1902600	biological_process	proton transmembrane transport
u	0004129	molecular_function	cytochrome-c oxidase activity
u	0005739	cellular_component	mitochondrion
u	0005743	cellular_component	mitochondrial inner membrane
u	0006119	biological_process	oxidative phosphorylation
u	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
u	0016491	molecular_function	oxidoreductase activity
u	0045277	cellular_component	respiratory chain complex IV
u	1902600	biological_process	proton transmembrane transport
v	0004129	molecular_function	cytochrome-c oxidase activity
v	0005739	cellular_component	mitochondrion
v	0005743	cellular_component	mitochondrial inner membrane
v	0005758	cellular_component	mitochondrial intermembrane space
v	0006119	biological_process	oxidative phosphorylation
v	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
v	0016491	molecular_function	oxidoreductase activity
v	0031966	cellular_component	mitochondrial membrane
v	0033617	biological_process	mitochondrial respiratory chain complex IV assembly
v	0045277	cellular_component	respiratory chain complex IV
v	0045333	biological_process	cellular respiration
v	1902600	biological_process	proton transmembrane transport
w	0004129	molecular_function	cytochrome-c oxidase activity
w	0005739	cellular_component	mitochondrion
w	0005743	cellular_component	mitochondrial inner membrane
w	0006119	biological_process	oxidative phosphorylation
w	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
w	0009060	biological_process	aerobic respiration
w	0016491	molecular_function	oxidoreductase activity
w	0030234	molecular_function	enzyme regulator activity
w	0045277	cellular_component	respiratory chain complex IV
w	0097250	biological_process	mitochondrial respirasome assembly
w	1902600	biological_process	proton transmembrane transport
x	0003674	molecular_function	molecular_function
x	0005739	cellular_component	mitochondrion
x	0005743	cellular_component	mitochondrial inner membrane
x	0008150	biological_process	biological_process
x	0045277	cellular_component	respiratory chain complex IV
x	0098803	cellular_component	respiratory chain complex

Functional Information from PROSITE/UniProt

site_id	PS00077
Number of Residues	55
Details	COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyiliipgfgiishvvstyskkpvfgeismvyamasigllgflvws..HH

Chain	Residue	Details
m	TRP237-HIS291

---

site_id	PS00143
Number of Residues	23
Details	INSULINASE Insulinase family, zinc-binding region signature. Ggsryatkd.GvAHLLNRFnFqNT

Chain	Residue	Details
B	GLY37-THR59

---

site_id	PS01329
Number of Residues	18
Details	COX6A Cytochrome c oxidase subunit VIa signature. IRsKpFfWGDGdKTlFwN

Chain	Residue	Details
w	ILE101-ASN118

---

site_id	PS00848
Number of Residues	23
Details	COX5B_1 Cytochrome c oxidase subunit Vb, zinc binding region signature. IMWlkptvnevarCweCGsvYKL

Chain	Residue	Details
p	ILE121-LEU143

---

site_id	PS00078
Number of Residues	49
Details	COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. ViHdfaipslgikvdatpgrlnqvsaliqregvfyga......CselCgtgHanM

Chain	Residue	Details
n	VAL184-MET232

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17761666","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	122
Details	Topological domain: {"description":"Mitochondrial matrix","evidences":[{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8031140","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	366
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"10873857","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CX5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	208
Details	Topological domain: {"description":"Mitochondrial intermembrane","evidences":[{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8031140","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	8
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"10873857","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1EZV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KB9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P84","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CX5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4PD4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P00157","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	234
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	24
Details	Topological domain: {"description":"Mitochondrial matrix","evidences":[{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9430684","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	306
Details	Domain: {"description":"Cytochrome c","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	74
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	18
Details	Compositional bias: {"description":"Acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	4
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"10873857","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1EZV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"10873857","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1EZV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	132
Details	Topological domain: {"description":"Mitochondrial matrix","evidences":[{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	268
Details	Topological domain: {"description":"Mitochondrial intermembrane","evidences":[{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	182
Details	Domain: {"description":"Rieske","evidences":[{"source":"PROSITE-ProRule","id":"PRU00628","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	6
Details	Region: {"description":"Hinge","evidences":[{"source":"PubMed","id":"30598556","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10873857","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11880631","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18390544","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1EZV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KB9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KYO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P84","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CX5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4PD4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	20
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	260
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	334
Details	Topological domain: {"description":"Mitochondrial matrix","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	150
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	556
Details	Topological domain: {"description":"Mitochondrial intermembrane","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	172
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	106
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	102
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	108
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	124
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	82
Details	Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	56
Details	Transmembrane: {"description":"Helical; Name=8","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	44
Details	Transmembrane: {"description":"Helical; Name=9","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	58
Details	Transmembrane: {"description":"Helical; Name=10","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	48
Details	Transmembrane: {"description":"Helical; Name=11","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	48
Details	Transmembrane: {"description":"Helical; Name=12","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598556","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	4
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598556","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P00396","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	4
Details	Cross-link: {"description":"1'-histidyl-3'-tyrosine (His-Tyr)","evidences":[{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17215247","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30598554","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17761666","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	86
Details	Domain: {"description":"CHCH","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	20
Details	Motif: {"description":"Cx9C motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	22
Details	Motif: {"description":"Cx10C motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01150","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	1
Details	M-CSA 208

Chain	Residue	Details
E	HIS181	covalently attached, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, radical stabiliser
C	SER206	electrostatic stabiliser, hydrogen bond donor, radical stabiliser
C	LYS228	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, radical stabiliser
C	ASP229	electrostatic stabiliser, hydrogen bond acceptor, radical stabiliser
C	GLU272	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, radical stabiliser

---

site_id	MCSA2
Number of Residues	1
Details	M-CSA 208

Chain

Residue

Details

---