9BIB
Rat GluN1-GluN2B NMDA receptor channel in complex with glycine, glutamate, and EU-1622-A, in open-channel conformation, C1 symmetry
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1408 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:24876489 |
| Chain | Residue | Details |
| A | ARG19-GLN559 | |
| A | THR648-ASN812 | |
| C | ARG19-GLN559 | |
| C | THR648-ASN812 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 112 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:24876489 |
| Chain | Residue | Details |
| A | SER560-LEU580 | |
| A | ILE631-TYR647 | |
| A | MET813-ILE833 | |
| C | SER560-LEU580 | |
| C | ILE631-TYR647 | |
| C | MET813-ILE833 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 52 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:24876489 |
| Chain | Residue | Details |
| A | ASP581-THR602 | |
| A | ARG625-ARG630 | |
| C | ASP581-THR602 | |
| C | ARG625-ARG630 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 42 |
| Details | INTRAMEM: Discontinuously helical => ECO:0000250|UniProtKB:A0A1L8F5J9 |
| Chain | Residue | Details |
| A | LEU603-PRO624 | |
| C | LEU603-PRO624 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24876489, ECO:0007744|PDB:1PB7, ECO:0007744|PDB:2A5T, ECO:0007744|PDB:4NF5, ECO:0007744|PDB:4NF6, ECO:0007744|PDB:4NF8, ECO:0007744|PDB:4PE5, ECO:0007744|PDB:5DEX, ECO:0007744|PDB:5I56, ECO:0007744|PDB:5I57, ECO:0007744|PDB:5I58, ECO:0007744|PDB:5I59, ECO:0007744|PDB:5U8C, ECO:0007744|PDB:5VIH, ECO:0007744|PDB:5VII, ECO:0007744|PDB:5VIJ |
| Chain | Residue | Details |
| A | PRO516 | |
| C | PRO516 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16281028, ECO:0000269|PubMed:24876489, ECO:0007744|PDB:1PB7, ECO:0007744|PDB:2A5T, ECO:0007744|PDB:4NF5, ECO:0007744|PDB:4NF6, ECO:0007744|PDB:4NF8, ECO:0007744|PDB:4PE5, ECO:0007744|PDB:5DEX, ECO:0007744|PDB:5I56, ECO:0007744|PDB:5I57, ECO:0007744|PDB:5I58, ECO:0007744|PDB:5I59, ECO:0007744|PDB:5U8C, ECO:0007744|PDB:5VIH, ECO:0007744|PDB:5VII, ECO:0007744|PDB:5VIJ |
| Chain | Residue | Details |
| A | ARG523 | |
| A | SER688 | |
| A | ASP732 | |
| C | ARG523 | |
| C | SER688 | |
| C | ASP732 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0007744|PDB:3Q41 |
| Chain | Residue | Details |
| A | GLN61 | |
| A | ASP239 | |
| C | GLN61 | |
| C | ASP239 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:24876489, ECO:0007744|PDB:3Q41, ECO:0007744|PDB:4PE5, ECO:0007744|PubMed:24090084 |
| Chain | Residue | Details |
| A | ASN203 | |
| A | ASN368 | |
| C | ASN203 | |
| C | ASN368 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:24876489, ECO:0007744|PDB:3Q41, ECO:0007744|PDB:4PE5 |
| Chain | Residue | Details |
| A | ASN276 | |
| C | ASN276 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:24876489, ECO:0007744|PDB:4PE5 |
| Chain | Residue | Details |
| A | ASN300 | |
| C | ASN300 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0007744|PubMed:24090084 |
| Chain | Residue | Details |
| A | GLN350 | |
| A | GLN771 | |
| C | GLN350 | |
| C | GLN771 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:24876489, ECO:0007744|PDB:4PE5, ECO:0007744|PubMed:24090084 |
| Chain | Residue | Details |
| A | ASN440 | |
| C | ASN440 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | GLN471 | |
| A | GLN491 | |
| A | ASN674 | |
| C | GLN471 | |
| C | GLN491 | |
| C | ASN674 |
