9BCZ
Chicken 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (PLCZ1) in complex with calcium and phosphorylated threonine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004435 | molecular_function | phosphatidylinositol-4,5-bisphosphate phospholipase C activity |
| A | 0004629 | molecular_function | phospholipase C activity |
| A | 0005546 | molecular_function | phosphatidylinositol-4,5-bisphosphate binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005730 | cellular_component | nucleolus |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006816 | biological_process | calcium ion transport |
| A | 0007165 | biological_process | signal transduction |
| A | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration |
| A | 0007338 | biological_process | single fertilization |
| A | 0007343 | biological_process | egg activation |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| A | 0010314 | molecular_function | phosphatidylinositol-5-phosphate binding |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0032266 | molecular_function | phosphatidylinositol-3-phosphate binding |
| A | 0035556 | biological_process | intracellular signal transduction |
| A | 0045120 | cellular_component | pronucleus |
| A | 0048471 | cellular_component | perinuclear region of cytoplasm |
| A | 0060470 | biological_process | positive regulation of cytosolic calcium ion concentration involved in egg activation |
| A | 0061827 | cellular_component | sperm head |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Domain: {"description":"EF-hand","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 145 |
| Details | Domain: {"description":"PI-PLC X-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00270","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 116 |
| Details | Domain: {"description":"PI-PLC Y-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00271","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 126 |
| Details | Domain: {"description":"C2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00041","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"UniProtKB","id":"P10688","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU00270","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
