Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000151 | cellular_component | ubiquitin ligase complex |
A | 0000209 | biological_process | protein polyubiquitination |
A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005524 | molecular_function | ATP binding |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
A | 0016567 | biological_process | protein ubiquitination |
A | 0016740 | molecular_function | transferase activity |
A | 0031146 | biological_process | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
A | 0031625 | molecular_function | ubiquitin protein ligase binding |
A | 0032933 | biological_process | SREBP signaling pathway |
A | 0045842 | biological_process | positive regulation of mitotic metaphase/anaphase transition |
A | 0061631 | molecular_function | ubiquitin conjugating enzyme activity |
Functional Information from PROSITE/UniProt
site_id | PS00183 |
Number of Residues | 16 |
Details | UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNInsn.GsICLdiL |
Chain | Residue | Details |
A | TYR74-LEU89 | |
site_id | PS00299 |
Number of Residues | 26 |
Details | UBIQUITIN_1 Ubiquitin domain signature. KskIqDkegIPpdqQrLIFaGkqleD |
Chain | Residue | Details |
B | LYS27-ASP52 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Glycyl thioester intermediate => ECO:0000305 |
Chain | Residue | Details |
C | CYS639 | |
B | LYS11 | |
B | LYS27 | |
B | LYS33 | |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250 |
Chain | Residue | Details |
B | LYS29 | |
B | LYS48 | |
B | LYS63 | |