9B3N

Human Notch-1 EGFs 20-24

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding

Functional Information from PROSITE/UniProt

site_id	PS00010
Number of Residues	12
Details	ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CkDmtsgYvCtC

Chain	Residue	Details
A	CYS768-CYS779
A	CYS806-CYS817
A	CYS884-CYS895

---

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CtCreGfsGPnC

Chain	Residue	Details
A	CYS777-CYS788
A	CYS815-CYS826
A	CYS855-CYS866
A	CYS893-CYS904
A	CYS931-CYS942

---

site_id	PS01186
Number of Residues	12
Details	EGF_2 EGF-like domain signature 2. CtCreGFsgpn....C

Chain	Residue	Details
A	CYS777-CYS788
A	CYS815-CYS826
A	CYS855-CYS866
A	CYS893-CYS904
A	CYS931-CYS942

---

site_id	PS01187
Number of Residues	25
Details	EGF_CA Calcium-binding EGF-like domain signature. NnNECesnp..........Cvnggt..CkDmtsgYvC

Chain	Residue	Details
A	ASN753-CYS777
A	ASN791-CYS815
A	ASP869-CYS893

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	Domain: {"description":"EGF-like 21; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	38
Details	Domain: {"description":"EGF-like 22","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	36
Details	Domain: {"description":"EGF-like 23; calcium-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	36
Details	Domain: {"description":"EGF-like 24","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (Glc...) serine","evidences":[{"source":"UniProtKB","id":"Q01705","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Glycosylation: {"description":"O-linked (Fuc...) threonine","evidences":[{"source":"UniProtKB","id":"Q01705","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"source":"UniProtKB","id":"Q01705","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Glycosylation: {"description":"O-linked (Fuc) serine","evidences":[{"source":"UniProtKB","id":"Q01705","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---