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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9AZJ

Structure of ubiquitinated NEMO UBAN K285C-Ub G76C bound to HOIP NZF1

Functional Information from PROSITE/UniProt
site_idPS00299
Number of Residues26
DetailsUBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD
ChainResidueDetails
FLYS27-ASP52
site_idPS01358
Number of Residues20
DetailsZF_RANBP2_1 Zinc finger RanBP2-type signature. WaCqs..CtfeNeaaavlCsiC
ChainResidueDetails
ETRP354-CYS373
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues21
DetailsRegion: {"description":"Leucine-zipper","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues14
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"21455181","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues8
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin and interchain with MARCHF2)","evidences":[{"source":"PubMed","id":"21455181","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32935379","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues4
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"14651848","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21455181","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues4
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"15620648","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17562858","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19136968","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21455181","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues4
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"14651848","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19136968","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20010814","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21455181","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues4
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"20010814","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues4
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"O88522","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

248335

PDB entries from 2026-01-28

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