Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1374 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-PRO100 | |
| A | GLU1556-SER1616 | |
| A | ARG1674-ARG1680 | |
| A | LEU1738-ASN1751 | |
| A | GLU1864-VAL2353 | |
| A | PHE161-ASP169 | |
| A | VAL213-ASN232 | |
| A | THR420-SER1073 | |
| A | LEU850-ASN855 | |
| A | VAL907-THR917 | |
| A | GLU1016-VAL1290 | |
| A | LEU1353-SER1362 | |
| A | VAL1419-ARG1428 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=S1 of repeat I => ECO:0000255 |
| Chain | Residue | Details |
| A | TRP101-MET119 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 433 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE120-ALA141 | |
| A | HIS1638-TYR1651 | |
| A | GLU1700-ILE1713 | |
| A | ARG1773-LEU1835 | |
| A | GLU185-VAL193 | |
| A | GLY254-TYR394 | |
| A | HIS815-ILE827 | |
| A | GLN875-VAL882 | |
| A | CYS939-TRP990 | |
| A | GLU1314-SER1331 | |
| A | MET1383-ARG1396 | |
| A | LYS1453-PRO1529 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=S2 of repeat I => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE142-LEU160 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 14 |
| Details | TRANSMEM: Helical; Name=S3 of repeat I => ECO:0000255 |
| Chain | Residue | Details |
| A | THR170-MET184 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=S4 of repeat I => ECO:0000255 |
| Chain | Residue | Details |
| A | SER194-ARG212 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=S5 of repeat I => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL233-ALA253 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=S6 of repeat I => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN395-ALA419 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=S1 of repeat II => ECO:0000255 |
| Chain | Residue | Details |
| A | TYR794-TYR814 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=S2 of repeat II => ECO:0000255 |
| Chain | Residue | Details |
| A | SER828-PRO849 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=S3 of repeat II => ECO:0000255 |
| Chain | Residue | Details |
| A | PRO856-GLY874 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=S4 of repeat II => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU883-VAL906 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=S5 of repeat II => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE918-GLY938 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=S6 of repeat II => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA991-VAL1015 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=S1 of repeat III => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE1291-LEU1313 |
| site_id | SWS_FT_FI16 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=S2 of repeat III => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN1332-LEU1352 |
| site_id | SWS_FT_FI17 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical; Name=S3 of repeat III => ECO:0000255 |
| Chain | Residue | Details |
| A | SER1363-ALA1382 |
| site_id | SWS_FT_FI18 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=S4 of repeat III => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL1397-LEU1418 |
| site_id | SWS_FT_FI19 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=S5 of repeat III => ECO:0000255 |
| Chain | Residue | Details |
| A | PRO1429-PHE1452 |
| site_id | SWS_FT_FI20 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical; Name=S6 of repeat III => ECO:0000255 |
| Chain | Residue | Details |
| A | TRP1530-VAL1555 |
| site_id | SWS_FT_FI21 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=S1 of repeat IV => ECO:0000255 |
| Chain | Residue | Details |
| A | HIS1617-GLU1637 |
| site_id | SWS_FT_FI22 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=S2 of repeat IV => ECO:0000255 |
| Chain | Residue | Details |
| A | CYS1652-PHE1673 |
| site_id | SWS_FT_FI23 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=S3 of repeat IV => ECO:0000255 |
| Chain | Residue | Details |
| A | TRP1681-GLU1699 |
| site_id | SWS_FT_FI24 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=S4 of repeat IV => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE1714-ALA1737 |
| site_id | SWS_FT_FI25 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=S5 of repeat IV => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU1752-GLY1772 |
| site_id | SWS_FT_FI26 |
| Number of Residues | 27 |
| Details | TRANSMEM: Helical; Name=S6 of repeat IV => ECO:0000255 |
| Chain | Residue | Details |
| A | SER1836-LEU1863 |
| site_id | SWS_FT_FI27 |
| Number of Residues | 3 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP140 | |
| A | ASP189 | |
| A | HIS191 |
| site_id | SWS_FT_FI28 |
| Number of Residues | 4 |
| Details | SITE: Calcium ion selectivity and permeability => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU378 | |
| A | GLU974 | |
| A | ASP1504 | |
| A | ASP1808 |
| site_id | SWS_FT_FI29 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN192 | |
| A | ASN271 | |
| A | ASN1466 |
