8ZMF
Crystal structure of an inverse agonist antipsychotic drug derivative-bound 5-HT2C
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
site_id | PS00237 |
Number of Residues | 17 |
Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ASImHLCAISLDRYVaI |
Chain | Residue | Details |
A | ALA140-ILE156 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 25 |
Details | TRANSMEM: Helical; Name=1 => ECO:0000250 |
Chain | Residue | Details |
A | GLN53-VAL78 |
site_id | SWS_FT_FI2 |
Number of Residues | 29 |
Details | TOPO_DOM: Cytoplasmic => ECO:0000250 |
Chain | Residue | Details |
A | SER79-ASN89 | |
A | ASP151-LYS170 |
site_id | SWS_FT_FI3 |
Number of Residues | 20 |
Details | TRANSMEM: Helical; Name=2 => ECO:0000250 |
Chain | Residue | Details |
A | TYR90-SER110 |
site_id | SWS_FT_FI4 |
Number of Residues | 49 |
Details | TOPO_DOM: Extracellular => ECO:0000250 |
Chain | Residue | Details |
A | LEU111-CYS127 | |
A | LEU194-ASN213 | |
A | SER334-LYS348 |
site_id | SWS_FT_FI5 |
Number of Residues | 22 |
Details | TRANSMEM: Helical; Name=3 => ECO:0000250 |
Chain | Residue | Details |
A | PRO128-LEU150 |
site_id | SWS_FT_FI6 |
Number of Residues | 22 |
Details | TRANSMEM: Helical; Name=4 => ECO:0000250 |
Chain | Residue | Details |
A | ALA171-GLY193 |
site_id | SWS_FT_FI7 |
Number of Residues | 21 |
Details | TRANSMEM: Helical; Name=5 => ECO:0000250 |
Chain | Residue | Details |
A | PHE214-CYS235 |
site_id | SWS_FT_FI8 |
Number of Residues | 21 |
Details | TRANSMEM: Helical; Name=6 => ECO:0000250 |
Chain | Residue | Details |
A | VAL312-LEU333 |
site_id | SWS_FT_FI9 |
Number of Residues | 22 |
Details | TRANSMEM: Helical; Name=7 => ECO:0000250 |
Chain | Residue | Details |
A | LEU349-PHE371 |
site_id | SWS_FT_FI10 |
Number of Residues | 3 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:P41595 |
Chain | Residue | Details |
A | ASP134 | |
A | THR139 | |
A | LEU209 |
site_id | SWS_FT_FI11 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 |
Chain | Residue | Details |
A | ASN204 |
site_id | SWS_FT_FI12 |
Number of Residues | 2 |
Details | BINDING: axial binding residue |
Chain | Residue | Details |
A | TRP1007 | |
A | ILE1102 |