8YP1

Crystal structure of HARS WHEP domain fused with Fc

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0006418	biological_process	tRNA aminoacylation for protein translation
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0006418	biological_process	tRNA aminoacylation for protein translation
C	0004812	molecular_function	aminoacyl-tRNA ligase activity
C	0005524	molecular_function	ATP binding
C	0006418	biological_process	tRNA aminoacylation for protein translation
D	0004812	molecular_function	aminoacyl-tRNA ligase activity
D	0005524	molecular_function	ATP binding
D	0006418	biological_process	tRNA aminoacylation for protein translation

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FSCSVMH

Chain	Residue	Details
A	PHE204-HIS210

---

site_id	PS00762
Number of Residues	29
Details	WHEP_TRS_1 WHEP-TRS domain signature. QGErVRglKqqKAsaelIEeeVakLlklK

Chain	Residue	Details
A	GLN241-LYS269

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	396
Details	Domain: {"description":"Ig-like 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	384
Details	Domain: {"description":"Ig-like 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"11406581","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19139490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19358553","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20357243","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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