8Y69
LGR4-RSPO2-ZNRF3 (2:2:2)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0016020 | cellular_component | membrane |
| A | 0016500 | molecular_function | protein-hormone receptor activity |
| D | 0004930 | molecular_function | G protein-coupled receptor activity |
| D | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| D | 0016020 | cellular_component | membrane |
| D | 0016500 | molecular_function | protein-hormone receptor activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 326 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| C | LYS56-MET219 | |
| H | LYS56-MET219 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| C | GLY220-ILE240 | |
| H | GLY220-ILE240 | |
| A | TYR725-ASN756 | |
| D | CYS566-LEU575 | |
| D | GLU642-GLN661 | |
| D | TYR725-ASN756 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE576-PHE596 | |
| D | PHE576-PHE596 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 96 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU597-VAL620 | |
| A | HIS683-SER703 | |
| A | SER778-LYS783 | |
| D | LEU597-VAL620 | |
| D | HIS683-SER703 | |
| D | SER778-LYS783 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA621-VAL641 | |
| D | ALA621-VAL641 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE662-PHE682 | |
| D | PHE662-PHE682 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU704-ILE724 | |
| D | LEU704-ILE724 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| A | CYS757-ILE777 | |
| D | CYS757-ILE777 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| A | SER784-PHE804 | |
| D | SER784-PHE804 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:23756652 |
| Chain | Residue | Details |
| A | ASN68 | |
| A | ASN199 | |
| D | ASN68 | |
| D | ASN199 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN294 | |
| A | ASN314 | |
| A | ASN505 | |
| D | ASN294 | |
| D | ASN314 | |
| D | ASN505 |
