8XPT
The Crystal Structure of EHMT1 from Biortus.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002039 | molecular_function | p53 binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| A | 0042054 | molecular_function | histone methyltransferase activity |
| A | 0046974 | molecular_function | histone H3K9 methyltransferase activity |
| B | 0002039 | molecular_function | p53 binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| B | 0042054 | molecular_function | histone methyltransferase activity |
| B | 0046974 | molecular_function | histone H3K9 methyltransferase activity |
| C | 0002039 | molecular_function | p53 binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| C | 0042054 | molecular_function | histone methyltransferase activity |
| C | 0046974 | molecular_function | histone H3K9 methyltransferase activity |
| D | 0002039 | molecular_function | p53 binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| D | 0042054 | molecular_function | histone methyltransferase activity |
| D | 0046974 | molecular_function | histone H3K9 methyltransferase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 252 |
| Details | Domain: {"description":"Pre-SET","evidences":[{"source":"PROSITE-ProRule","id":"PRU00157","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 234 |
| Details | Domain: {"description":"SET","evidences":[{"source":"PROSITE-ProRule","id":"PRU00190","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 41 |
| Details | Region: {"description":"Interaction with histone H3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 72 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Site: {"description":"Histone H3K9me binding","evidences":[{"source":"PubMed","id":"18264113","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20084102","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
