8XOK
Cryo-EM structure of human ABCC4
Functional Information from PROSITE/UniProt
| site_id | PS00211 |
| Number of Residues | 15 |
| Details | ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQKARVNLARAV |
| Chain | Residue | Details |
| A | LEU535-VAL549 | |
| A | PHE1177-ILE1191 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 280 |
| Details | TRANSMEM: Helical => ECO:0000255|PROSITE-ProRule:PRU00441 |
| Chain | Residue | Details |
| A | LEU93-LEU113 | |
| A | LEU836-VAL856 | |
| A | VAL858-LEU878 | |
| A | ALA954-LEU974 | |
| A | GLY977-VAL997 | |
| A | GLU1038-LEU1058 | |
| A | ALA136-PHE156 | |
| A | GLN207-ALA227 | |
| A | LEU228-LEU248 | |
| A | SER328-ALA348 | |
| A | VAL351-SER371 | |
| A | LEU440-GLY460 | |
| A | HIS710-LEU730 | |
| A | LEU771-VAL791 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00434 |
| Chain | Residue | Details |
| A | GLY445 | |
| A | GLY1075 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | THR646 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | THR648 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER664 | |
| A | SER668 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:26721430 |
| Chain | Residue | Details |
| A | ASN746 | |
| A | ASN754 |
