8XC1
C. elegans SID1 in complex with dsRNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003725 | molecular_function | double-stranded RNA binding |
| A | 0005764 | cellular_component | lysosome |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0031047 | biological_process | regulatory ncRNA-mediated gene silencing |
| A | 0033227 | biological_process | dsRNA transport |
| A | 0035194 | biological_process | regulatory ncRNA-mediated post-transcriptional gene silencing |
| A | 0050658 | biological_process | RNA transport |
| A | 0051033 | molecular_function | RNA transmembrane transporter activity |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003725 | molecular_function | double-stranded RNA binding |
| B | 0005764 | cellular_component | lysosome |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0031047 | biological_process | regulatory ncRNA-mediated gene silencing |
| B | 0033227 | biological_process | dsRNA transport |
| B | 0035194 | biological_process | regulatory ncRNA-mediated post-transcriptional gene silencing |
| B | 0050658 | biological_process | RNA transport |
| B | 0051033 | molecular_function | RNA transmembrane transporter activity |
Functional Information from PROSITE/UniProt
| site_id | PS00284 |
| Number of Residues | 11 |
| Details | SERPIN Serpins signature. LELDQSFILdL |
| Chain | Residue | Details |
| A | LEU61-LEU71 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 752 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | GLN18-ALA319 | |
| B | SER597-THR599 | |
| B | ALA655-ASN659 | |
| B | ASP713-ASP741 | |
| A | LYS451-ASN481 | |
| A | GLN532-PRO543 | |
| A | SER597-THR599 | |
| A | ALA655-ASN659 | |
| A | ASP713-ASP741 | |
| B | GLN18-ALA319 | |
| B | LYS451-ASN481 | |
| B | GLN532-PRO543 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 440 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU320-ILE340 | |
| A | ALA692-GLN712 | |
| A | LEU742-ASP762 | |
| B | LEU320-ILE340 | |
| B | MET430-HIS450 | |
| B | ASN482-CYS502 | |
| B | HIS511-LEU531 | |
| B | SER544-VAL564 | |
| B | PRO576-PHE596 | |
| B | SER600-ALA620 | |
| B | PHE634-SER654 | |
| A | MET430-HIS450 | |
| B | GLN660-MET680 | |
| B | ALA692-GLN712 | |
| B | LEU742-ASP762 | |
| A | ASN482-CYS502 | |
| A | HIS511-LEU531 | |
| A | SER544-VAL564 | |
| A | PRO576-PHE596 | |
| A | SER600-ALA620 | |
| A | PHE634-SER654 | |
| A | GLN660-MET680 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 280 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | LYS341-GLN429 | |
| B | LYS621-ARG633 | |
| B | LYS681-LYS691 | |
| B | ASP763-PHE776 | |
| A | ARG503-SER510 | |
| A | ARG565-SER575 | |
| A | LYS621-ARG633 | |
| A | LYS681-LYS691 | |
| A | ASP763-PHE776 | |
| B | LYS341-GLN429 | |
| B | ARG503-SER510 | |
| B | ARG565-SER575 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 14 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN19 | |
| B | ASN32 | |
| B | ASN205 | |
| B | ASN210 | |
| B | ASN234 | |
| B | ASN311 | |
| A | ASN20 | |
| A | ASN32 | |
| A | ASN205 | |
| A | ASN210 | |
| A | ASN234 | |
| A | ASN311 | |
| B | ASN19 | |
| B | ASN20 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17761667 |
| Chain | Residue | Details |
| A | ASN290 | |
| B | ASN290 |
