8X20
HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:E-CFCP-TP ternary complex
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP110 | |
| C | ASP186 | |
| C | ASP443 | |
| C | GLU478 | |
| C | ASP498 | |
| C | ASP549 | |
| A | ASP185 | |
| A | ASP186 | |
| A | ASP443 | |
| A | GLU478 | |
| A | ASP498 | |
| A | ASP549 | |
| C | ASP110 | |
| C | ASP185 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Essential for RT p66/p51 heterodimerization => ECO:0000250 |
| Chain | Residue | Details |
| A | TRP401 | |
| A | TRP414 | |
| C | TRP401 | |
| C | TRP414 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease; partial => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE440 | |
| C | PHE440 |
