8WWZ

Crystal structure of Bacillus subtilis glyceraldehyde-3-phosphate dehydrogenase GapB

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004365	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0006006	biological_process	glucose metabolic process
A	0006094	biological_process	gluconeogenesis
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0030554	molecular_function	adenyl nucleotide binding
A	0043891	molecular_function	glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity
A	0044281	biological_process	small molecule metabolic process
A	0047100	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity
A	0050661	molecular_function	NADP binding
A	0051287	molecular_function	NAD binding

Functional Information from PROSITE/UniProt

site_id	PS00071
Number of Residues	8
Details	GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL

Chain	Residue	Details
A	ALA150-LEU157

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000250|UniProtKB:P00362

Chain	Residue	Details
A	CYS152

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site_id	SWS_FT_FI2
Number of Residues	10
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P00362

Chain	Residue	Details
A	ARG12
A	ASN315
A	ARG78
A	THR120
A	SER151
A	THR182
A	ASN183
A	ARG197
A	THR210
A	ARG233

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Activates thiol group during catalysis => ECO:0000250|UniProtKB:Q6GIL8

Chain	Residue	Details
A	HIS179

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