8W92
human H ferritin with 2 Fe(II)/subunit loading
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:1992356, ECO:0007744|PDB:1FHA |
| Chain | Residue | Details |
| A | GLU27 | |
| A | HIS65 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00085 |
| Chain | Residue | Details |
| A | GLU62 | |
| A | GLU107 | |
| A | GLN141 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Essential for association with cargo receptor NCOA4 => ECO:0000269|PubMed:26436293 |
| Chain | Residue | Details |
| A | ARG22 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| A | MET0 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylthreonine; in Ferritin heavy chain, N-terminally processed => ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| A | THR1 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18318008, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER178 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18318008 |
| Chain | Residue | Details |
| A | SER182 |
