8W4B
The sigma-1 receptor from Xenopus laevis in complex with progesterone by co-crystallization
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005635 | cellular_component | nuclear envelope |
| A | 0005637 | cellular_component | nuclear inner membrane |
| A | 0005640 | cellular_component | nuclear outer membrane |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0014069 | cellular_component | postsynaptic density |
| A | 0016020 | cellular_component | membrane |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0038023 | molecular_function | signaling receptor activity |
| A | 0043523 | biological_process | regulation of neuron apoptotic process |
| A | 1905897 | biological_process | regulation of response to endoplasmic reticulum stress |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Topological domain: {"description":"Lumenal","evidences":[{"source":"UniProtKB","id":"Q99720","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"UniProtKB","id":"Q99720","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Region: {"description":"Important for ligand-binding","evidences":[{"source":"UniProtKB","id":"Q60492","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for ligand binding","evidences":[{"source":"UniProtKB","id":"Q99720","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
