8W4B
The sigma-1 receptor from Xenopus laevis in complex with progesterone by co-crystallization
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0005635 | cellular_component | nuclear envelope |
| A | 0005637 | cellular_component | nuclear inner membrane |
| A | 0005640 | cellular_component | nuclear outer membrane |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0006869 | biological_process | lipid transport |
| A | 0016020 | cellular_component | membrane |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | TOPO_DOM: Lumenal => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | MET1-TRP4 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | LEU5-LEU27 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 193 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | SER28-PHE221 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Important for ligand binding => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | ASP123 | |
| A | GLU169 |
