8VZA

Crystal Structure of 2-Hydroxacyl-CoA Lyase/Synthase ApbHACS from Alphaproteobacteria bacterium in the Complex with THDP, L-Lactyl-CoA, and ADP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0001561	biological_process	fatty acid alpha-oxidation
A	0003824	molecular_function	catalytic activity
A	0016830	molecular_function	carbon-carbon lyase activity
A	0030976	molecular_function	thiamine pyrophosphate binding
A	0046395	biological_process	carboxylic acid catabolic process
B	0000287	molecular_function	magnesium ion binding
B	0001561	biological_process	fatty acid alpha-oxidation
B	0003824	molecular_function	catalytic activity
B	0016830	molecular_function	carbon-carbon lyase activity
B	0030976	molecular_function	thiamine pyrophosphate binding
B	0046395	biological_process	carboxylic acid catabolic process
C	0000287	molecular_function	magnesium ion binding
C	0001561	biological_process	fatty acid alpha-oxidation
C	0003824	molecular_function	catalytic activity
C	0016830	molecular_function	carbon-carbon lyase activity
C	0030976	molecular_function	thiamine pyrophosphate binding
C	0046395	biological_process	carboxylic acid catabolic process
D	0000287	molecular_function	magnesium ion binding
D	0001561	biological_process	fatty acid alpha-oxidation
D	0003824	molecular_function	catalytic activity
D	0016830	molecular_function	carbon-carbon lyase activity
D	0030976	molecular_function	thiamine pyrophosphate binding
D	0046395	biological_process	carboxylic acid catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00187
Number of Residues	20
Details	TPP_ENZYMES Thiamine pyrophosphate enzymes signature. VAaaavhPgrpvIaVqGDSA

Chain	Residue	Details
A	VAL428-ALA447

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