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8VUP

E. coli 70S ribosome with unmodified tRNAPro(GGG) in the e*/E conformation on a slippery CCC-C codon

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0000049molecular_functiontRNA binding
A0003723molecular_functionRNA binding
A0005840cellular_componentribosome
A0006412biological_processtranslation
A0006417biological_processregulation of translation
A0019843molecular_functionrRNA binding
A0022625cellular_componentcytosolic large ribosomal subunit
A1990904cellular_componentribonucleoprotein complex
B0000027biological_processribosomal large subunit assembly
B0002181biological_processcytoplasmic translation
B0003723molecular_functionRNA binding
B0003735molecular_functionstructural constituent of ribosome
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005840cellular_componentribosome
B0006412biological_processtranslation
B0008270molecular_functionzinc ion binding
B0015934cellular_componentlarge ribosomal subunit
B0019843molecular_functionrRNA binding
B0022625cellular_componentcytosolic large ribosomal subunit
B0032297biological_processnegative regulation of DNA-templated DNA replication initiation
B1990904cellular_componentribonucleoprotein complex
C0000027biological_processribosomal large subunit assembly
C0002181biological_processcytoplasmic translation
C0003723molecular_functionRNA binding
C0003735molecular_functionstructural constituent of ribosome
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005840cellular_componentribosome
C0006412biological_processtranslation
C0019843molecular_functionrRNA binding
C0022625cellular_componentcytosolic large ribosomal subunit
C1990904cellular_componentribonucleoprotein complex
D0003723molecular_functionRNA binding
D0003735molecular_functionstructural constituent of ribosome
D0005840cellular_componentribosome
D0006412biological_processtranslation
D0019843molecular_functionrRNA binding
D1990904cellular_componentribonucleoprotein complex
E0000049molecular_functiontRNA binding
E0003723molecular_functionRNA binding
E0005840cellular_componentribosome
E0006412biological_processtranslation
E0019843molecular_functionrRNA binding
E1990904cellular_componentribonucleoprotein complex
F0002181biological_processcytoplasmic translation
F0003723molecular_functionRNA binding
F0003735molecular_functionstructural constituent of ribosome
F0005840cellular_componentribosome
F0006412biological_processtranslation
F0019843molecular_functionrRNA binding
F0022625cellular_componentcytosolic large ribosomal subunit
F1990904cellular_componentribonucleoprotein complex
G0003723molecular_functionRNA binding
G0005840cellular_componentribosome
G0006412biological_processtranslation
G0019843molecular_functionrRNA binding
G1990904cellular_componentribonucleoprotein complex
K0003723molecular_functionRNA binding
K0003735molecular_functionstructural constituent of ribosome
K0005840cellular_componentribosome
K0006412biological_processtranslation
K0019843molecular_functionrRNA binding
K0022625cellular_componentcytosolic large ribosomal subunit
K0070180molecular_functionlarge ribosomal subunit rRNA binding
K1990904cellular_componentribonucleoprotein complex
L0003723molecular_functionRNA binding
L0003735molecular_functionstructural constituent of ribosome
L0005840cellular_componentribosome
L0006412biological_processtranslation
L0019843molecular_functionrRNA binding
L0022625cellular_componentcytosolic large ribosomal subunit
L0046872molecular_functionmetal ion binding
L1990904cellular_componentribonucleoprotein complex
M0000027biological_processribosomal large subunit assembly
M0000049molecular_functiontRNA binding
M0002181biological_processcytoplasmic translation
M0003723molecular_functionRNA binding
M0003735molecular_functionstructural constituent of ribosome
M0005737cellular_componentcytoplasm
M0005840cellular_componentribosome
M0006412biological_processtranslation
M0019843molecular_functionrRNA binding
M0022625cellular_componentcytosolic large ribosomal subunit
M1990904cellular_componentribonucleoprotein complex
N0003735molecular_functionstructural constituent of ribosome
N0005840cellular_componentribosome
N0006412biological_processtranslation
N0015934cellular_componentlarge ribosomal subunit
N0022625cellular_componentcytosolic large ribosomal subunit
N0046872molecular_functionmetal ion binding
N1990904cellular_componentribonucleoprotein complex
P0003735molecular_functionstructural constituent of ribosome
P0005829cellular_componentcytosol
P0005840cellular_componentribosome
P0006412biological_processtranslation
P0022625cellular_componentcytosolic large ribosomal subunit
P1990904cellular_componentribonucleoprotein complex
Q0000027biological_processribosomal large subunit assembly
Q0003723molecular_functionRNA binding
Q0005840cellular_componentribosome
Q0019843molecular_functionrRNA binding
Q1990904cellular_componentribonucleoprotein complex
R0003723molecular_functionRNA binding
R0003735molecular_functionstructural constituent of ribosome
R0005737cellular_componentcytoplasm
R0005840cellular_componentribosome
R0006412biological_processtranslation
R0019843molecular_functionrRNA binding
R0046872molecular_functionmetal ion binding
R1990904cellular_componentribonucleoprotein complex
S0002181biological_processcytoplasmic translation
S0003723molecular_functionRNA binding
S0003735molecular_functionstructural constituent of ribosome
S0005515molecular_functionprotein binding
S0005737cellular_componentcytoplasm
S0005829cellular_componentcytosol
S0005840cellular_componentribosome
S0006412biological_processtranslation
S0015934cellular_componentlarge ribosomal subunit
S0019843molecular_functionrRNA binding
S0022625cellular_componentcytosolic large ribosomal subunit
S0042255biological_processribosome assembly
S0042256biological_processcytosolic ribosome assembly
S0046677biological_processresponse to antibiotic
S0070180molecular_functionlarge ribosomal subunit rRNA binding
S1902626biological_processassembly of large subunit precursor of preribosome
S1990904cellular_componentribonucleoprotein complex
T0003723molecular_functionRNA binding
T0005840cellular_componentribosome
T0006412biological_processtranslation
T0019843molecular_functionrRNA binding
T1990904cellular_componentribonucleoprotein complex
X0003735molecular_functionstructural constituent of ribosome
X0005840cellular_componentribosome
X0006412biological_processtranslation
X0022625cellular_componentcytosolic large ribosomal subunit
X1990904cellular_componentribonucleoprotein complex
Z0000027biological_processribosomal large subunit assembly
Z0002181biological_processcytoplasmic translation
Z0003735molecular_functionstructural constituent of ribosome
Z0005737cellular_componentcytoplasm
Z0005840cellular_componentribosome
Z0006412biological_processtranslation
Z0022625cellular_componentcytosolic large ribosomal subunit
Z1990904cellular_componentribonucleoprotein complex
b0005840cellular_componentribosome
b0006412biological_processtranslation
b1990904cellular_componentribonucleoprotein complex
d0005840cellular_componentribosome
d0006412biological_processtranslation
d1990904cellular_componentribonucleoprotein complex
f0005737cellular_componentcytoplasm
f0005840cellular_componentribosome
f0006412biological_processtranslation
f0046872molecular_functionmetal ion binding
f1990904cellular_componentribonucleoprotein complex
i0003723molecular_functionRNA binding
i0003735molecular_functionstructural constituent of ribosome
i0005840cellular_componentribosome
i0006412biological_processtranslation
i0015935cellular_componentsmall ribosomal subunit
i0019843molecular_functionrRNA binding
i0042274biological_processribosomal small subunit biogenesis
i0046872molecular_functionmetal ion binding
i1990904cellular_componentribonucleoprotein complex
m0003723molecular_functionRNA binding
m0005737cellular_componentcytoplasm
m0005840cellular_componentribosome
m0006412biological_processtranslation
m0019843molecular_functionrRNA binding
m1990904cellular_componentribonucleoprotein complex
n0000028biological_processribosomal small subunit assembly
n0003723molecular_functionRNA binding
n0003735molecular_functionstructural constituent of ribosome
n0005737cellular_componentcytoplasm
n0005840cellular_componentribosome
n0006412biological_processtranslation
n0015935cellular_componentsmall ribosomal subunit
n0022627cellular_componentcytosolic small ribosomal subunit
n1990904cellular_componentribonucleoprotein complex
o0000049molecular_functiontRNA binding
o0005840cellular_componentribosome
o0006412biological_processtranslation
o1990904cellular_componentribonucleoprotein complex
p0000028biological_processribosomal small subunit assembly
p0003723molecular_functionRNA binding
p0003735molecular_functionstructural constituent of ribosome
p0005840cellular_componentribosome
p0006412biological_processtranslation
p0019843molecular_functionrRNA binding
p0022627cellular_componentcytosolic small ribosomal subunit
p1990904cellular_componentribonucleoprotein complex
q0000028biological_processribosomal small subunit assembly
q0000049molecular_functiontRNA binding
q0003723molecular_functionRNA binding
q0003735molecular_functionstructural constituent of ribosome
q0005840cellular_componentribosome
q0006412biological_processtranslation
q0019843molecular_functionrRNA binding
q0022627cellular_componentcytosolic small ribosomal subunit
q0046872molecular_functionmetal ion binding
q1990904cellular_componentribonucleoprotein complex
r0000049molecular_functiontRNA binding
r0003723molecular_functionRNA binding
r0005829cellular_componentcytosol
r0005840cellular_componentribosome
r0006412biological_processtranslation
r0015935cellular_componentsmall ribosomal subunit
r0019843molecular_functionrRNA binding
r1990904cellular_componentribonucleoprotein complex
u0000028biological_processribosomal small subunit assembly
u0003735molecular_functionstructural constituent of ribosome
u0005737cellular_componentcytoplasm
u0005840cellular_componentribosome
u0006412biological_processtranslation
u0015935cellular_componentsmall ribosomal subunit
u0022627cellular_componentcytosolic small ribosomal subunit
u1990904cellular_componentribonucleoprotein complex
y0000028biological_processribosomal small subunit assembly
y0003723molecular_functionRNA binding
y0003735molecular_functionstructural constituent of ribosome
y0005829cellular_componentcytosol
y0005840cellular_componentribosome
y0006412biological_processtranslation
y0015935cellular_componentsmall ribosomal subunit
y0019843molecular_functionrRNA binding
y0022627cellular_componentcytosolic small ribosomal subunit
y0070181molecular_functionsmall ribosomal subunit rRNA binding
y1990904cellular_componentribonucleoprotein complex
z0000028biological_processribosomal small subunit assembly
z0002181biological_processcytoplasmic translation
z0003723molecular_functionRNA binding
z0003735molecular_functionstructural constituent of ribosome
z0005737cellular_componentcytoplasm
z0005829cellular_componentcytosol
z0005840cellular_componentribosome
z0006412biological_processtranslation
z0019843molecular_functionrRNA binding
z0022627cellular_componentcytosolic small ribosomal subunit
z1990904cellular_componentribonucleoprotein complex
Functional Information from PROSITE/UniProt
site_idPS00049
Number of Residues27
DetailsRIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtkkgvrrp.DGsvirFdgNacVL
ChainResidueDetails
KALA60-LEU86

site_idPS00052
Number of Residues27
DetailsRIBOSOMAL_S7 Ribosomal protein S7 signature. SeLlakFVnilmvdGKKstaesIVysA
ChainResidueDetails
lSER19-ALA45

site_idPS00053
Number of Residues18
DetailsRIBOSOMAL_S8 Ribosomal protein S8 signature. GiaVVSTSkGVMtdraAR
ChainResidueDetails
mGLY99-ARG116

site_idPS00054
Number of Residues23
DetailsRIBOSOMAL_S11 Ribosomal protein S11 signature. IrALnaA.GFrItnitDvTPiPHN
ChainResidueDetails
pILE96-ASN118

site_idPS00055
Number of Residues8
DetailsRIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR
ChainResidueDetails
qLYS42-ARG49

site_idPS00056
Number of Residues13
DetailsRIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIrEcRPLS
ChainResidueDetails
vGLY55-SER67

site_idPS00057
Number of Residues24
DetailsRIBOSOMAL_S18 Ribosomal protein S18 signature. IDYkd.IatLknYITEs.GKIvpsRI
ChainResidueDetails
wILE20-ILE43

site_idPS00061
Number of Residues29
DetailsADH_SHORT Short-chain dehydrogenases/reductases family signature. PdhkhavialTsiYGVGKTRSkAILaAAG
ChainResidueDetails
rPRO9-GLY37

site_idPS00323
Number of Residues25
DetailsRIBOSOMAL_S19 Ribosomal protein S19 signature. NGRqhvpvfVtdemVGhkLGEFapT
ChainResidueDetails
xASN52-THR76

site_idPS00358
Number of Residues17
DetailsRIBOSOMAL_L5 Ribosomal protein L5 signature. LaaISGQkpLiTkARkS
ChainResidueDetails
ELEU56-SER72

site_idPS00360
Number of Residues19
DetailsRIBOSOMAL_S9 Ribosomal protein S9 signature. GGGisGQagAirhGiTRAL
ChainResidueDetails
nGLY68-LEU86

site_idPS00361
Number of Residues16
DetailsRIBOSOMAL_S10 Ribosomal protein S10 signature. AkrtGAqvrGPIpLPT
ChainResidueDetails
oALA29-THR44

site_idPS00362
Number of Residues31
DetailsRIBOSOMAL_S15 Ribosomal protein S15 signature. LqgHFaehKkDhhSrrgLlrMvsqrrkLldY
ChainResidueDetails
tLEU38-TYR68

site_idPS00430
Number of Residues66
DetailsTONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mireerllkvlraphvsekastameksntivlkvakdatkaeikaavqklfevevevv.........................................................NTLVVKGK
ChainResidueDetails
TMET1-LYS66

site_idPS00464
Number of Residues25
DetailsRIBOSOMAL_L22 Ribosomal protein L22 signature. KriMpRAkGRadrilkrtSHITVvV
ChainResidueDetails
SLYS83-VAL107

site_idPS00467
Number of Residues12
DetailsRIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGTAmNPvD
ChainResidueDetails
BPRO217-ASP228

site_idPS00474
Number of Residues24
DetailsRIBOSOMAL_L3 Ribosomal protein L3 signature. FadvkkvDvtGtSkGKGfaGtvkR
ChainResidueDetails
CPHE101-ARG124

site_idPS00475
Number of Residues31
DetailsRIBOSOMAL_L15 Ribosomal protein L15 signature. KVILaGeVttp..VtVrglrVTkgAraaIeaaG
ChainResidueDetails
LLYS109-GLY139

site_idPS00525
Number of Residues9
DetailsRIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGV
ChainResidueDetails
FPRO153-VAL161

site_idPS00527
Number of Residues23
DetailsRIBOSOMAL_S14 Ribosomal protein S14 signature. R.CrqtgrphgflrkFGLSRiKVR
ChainResidueDetails
sARG62-ARG84

site_idPS00548
Number of Residues35
DetailsRIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewyreGrVplHt..LradIDyntseahTtyGviG
ChainResidueDetails
hALA162-GLY196

site_idPS00579
Number of Residues15
DetailsRIBOSOMAL_L29 Ribosomal protein L29 signature. QSHLLKqVRRDVARV
ChainResidueDetails
YGLN39-VAL53

site_idPS00582
Number of Residues20
DetailsRIBOSOMAL_L33 Ribosomal protein L33 signature. YtTtKNkrtkPekLElkKFD
ChainResidueDetails
cTYR20-ASP39

site_idPS00585
Number of Residues33
DetailsRIBOSOMAL_S5 Ribosomal protein S5 signature. GRifsFtAltVVGDgn.GrVGfGygkar.EVpa.AI
ChainResidueDetails
jGLY27-ILE59

site_idPS00586
Number of Residues12
DetailsRIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRqGKIWIRVFP
ChainResidueDetails
MLYS58-PRO69

site_idPS00632
Number of Residues25
DetailsRIBOSOMAL_S4 Ribosomal protein S4 signature. LEgRLdnvVYRmgfGaTraeARqLV
ChainResidueDetails
iLEU93-VAL117

site_idPS00634
Number of Residues33
DetailsRIBOSOMAL_L30 Ribosomal protein L30 signature. TLlgLgLrRigHtVeredtpairgMInaVsfMV
ChainResidueDetails
ZTHR22-VAL54

site_idPS00646
Number of Residues14
DetailsRIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ
ChainResidueDetails
rARG86-GLN99

site_idPS00651
Number of Residues28
DetailsRIBOSOMAL_L9 Ribosomal protein L9 signature. GslGdqvnVkaGYarNFLvpqgkAvpaT
ChainResidueDetails
GGLY13-THR40

site_idPS00701
Number of Residues12
DetailsRIBOSOMAL_L16_2 Ribosomal protein L16 signature 2. RMGkGKGnveyW
ChainResidueDetails
MARG81-TRP92

site_idPS00732
Number of Residues10
DetailsRIBOSOMAL_S16 Ribosomal protein S16 signature. VtIRLARHGA
ChainResidueDetails
uVAL2-ALA11

site_idPS00783
Number of Residues23
DetailsRIBOSOMAL_L13 Ribosomal protein L13 signature. VKGMLPkgpl.GRamfrkLkVYaG
ChainResidueDetails
JVAL105-GLY127

site_idPS00784
Number of Residues20
DetailsRIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpsvlkRnrsh.GFraR
ChainResidueDetails
dLYS2-ARG21

site_idPS00828
Number of Residues27
DetailsRIBOSOMAL_L36 Ribosomal protein L36 signature. CrnCkiVkRdgvIrViCsaepKHkQrQ
ChainResidueDetails
fCYS11-GLN37

site_idPS00831
Number of Residues15
DetailsRIBOSOMAL_L27 Ribosomal protein L27 signature. GsIIvRQRGtkfhaG
ChainResidueDetails
WGLY30-GLY44

site_idPS00936
Number of Residues27
DetailsRIBOSOMAL_L35 Ribosomal protein L35 signature. KTVrGAaKRFkktgkggfkhkhanl.RH
ChainResidueDetails
eLYS4-HIS30

site_idPS00937
Number of Residues17
DetailsRIBOSOMAL_L20 Ribosomal protein L20 signature. KrqfRqLWIARINaaaR
ChainResidueDetails
QLYS53-ARG69

site_idPS01015
Number of Residues16
DetailsRIBOSOMAL_L19 Ribosomal protein L19 signature. VkRrGAVR.KAKLYYLR
ChainResidueDetails
PVAL85-ARG100

site_idPS01048
Number of Residues10
DetailsRIBOSOMAL_S6 Ribosomal protein S6 signature. GrRQLAYpIN
ChainResidueDetails
kGLY43-ASN52

site_idPS01108
Number of Residues18
DetailsRIBOSOMAL_L24 Ribosomal protein L24 signature. DDeViVLtGkdKGkr.GkV
ChainResidueDetails
UASP7-VAL24

site_idPS01167
Number of Residues23
DetailsRIBOSOMAL_L17 Ribosomal protein L17 signature. IkTTlpKaKelrrvvEpLITlAK
ChainResidueDetails
NILE34-LYS56

site_idPS01169
Number of Residues23
DetailsRIBOSOMAL_L21 Ribosomal protein L21 signature. VkivKfrrRKhyrkqqGHRQwfT
ChainResidueDetails
RVAL72-THR94

site_idPS01181
Number of Residues13
DetailsRIBOSOMAL_S21 Ribosomal protein S21 signature. DvALRRFKRsceK
ChainResidueDetails
zASP12-LYS24

site_idPS01199
Number of Residues19
DetailsRIBOSOMAL_L1 Ribosomal protein L1 signature. MrvVgq.LGqvLGPRGlMPN
ChainResidueDetails
AMET121-ASN139

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues52
DetailsRegion: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues9
DetailsCompositional bias: {"description":"Low complexity","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues2
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"18723842","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues1
DetailsModified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues1
DetailsModified residue: {"description":"N5-methylglutamine","evidences":[{"source":"PubMed","id":"365579","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"331083","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

site_idSWS_FT_FI16
Number of Residues1
DetailsModified residue: {"description":"N-methylmethionine","evidences":[{"source":"PubMed","id":"786730","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI17
Number of Residues1
DetailsModified residue: {"description":"(3R)-3-hydroxyarginine","evidences":[{"source":"PubMed","id":"23103944","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI18
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"34403461","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34504068","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O19","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7O1A","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7O1C","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OIZ","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7OJ0","evidenceCode":"ECO:0000312"}]}
ChainResidueDetails

site_idSWS_FT_FI19
Number of Residues68
DetailsDomain: {"description":"KH type-2"}
ChainResidueDetails

site_idSWS_FT_FI24
Number of Residues13
DetailsCompositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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