8VTV
Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with macrolone MCX-91, mRNA, aminoacylated A-site Phe-tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.55A resolution
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00049 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtkkeikrp.DGsairFddNaaVI |
| Chain | Residue | Details |
| 1O | ALA60-ILE86 |
| site_id | PS00052 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_S7 Ribosomal protein S7 signature. DvLvtaFInkimrdGKKnlaarIFydA |
| Chain | Residue | Details |
| 1g | ASP20-ALA46 |
| site_id | PS00053 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaILSTSkGVLtdreAR |
| Chain | Residue | Details |
| 1h | GLY108-ARG125 |
| site_id | PS00054 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALqaS.GLqVksivDdTPvPHN |
| Chain | Residue | Details |
| 1k | ILE95-ASN117 |
| site_id | PS00055 |
| Number of Residues | 8 |
| Details | RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR |
| Chain | Residue | Details |
| 1l | LYS46-ARG53 |
| site_id | PS00056 |
| Number of Residues | 13 |
| Details | RIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIiEsRPIS |
| Chain | Residue | Details |
| 1q | GLY54-SER66 |
| site_id | PS00057 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_S18 Ribosomal protein S18 signature. RDYrn.VevLkrFLSEt.GKIlprRR |
| Chain | Residue | Details |
| 2r | ARG32-ARG55 |
| site_id | PS00063 |
| Number of Residues | 16 |
| Details | ALDOKETO_REDUCTASE_3 Aldo/keto reductase family putative active site signature. LAKTIKraRIlGLlPF |
| Chain | Residue | Details |
| 2r | LEU66-PHE81 |
| site_id | PS00196 |
| Number of Residues | 16 |
| Details | COPPER_BLUE Type-1 copper (blue) proteins signature. GrvY.VICenPkHkqr.Q |
| Chain | Residue | Details |
| 19 | GLY21-GLN36 |
| site_id | PS00323 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKqhvpvyItenmVGhkLGEFapT |
| Chain | Residue | Details |
| 2s | ASN53-THR77 |
| site_id | PS00358 |
| Number of Residues | 17 |
| Details | RIBOSOMAL_L5 Ribosomal protein L5 signature. LalITGQkpAvTrAKkS |
| Chain | Residue | Details |
| 1G | LEU60-SER76 |
| site_id | PS00360 |
| Number of Residues | 19 |
| Details | RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGksGQidAiklGiARAL |
| Chain | Residue | Details |
| 1i | GLY67-LEU85 |
| site_id | PS00361 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_S10 Ribosomal protein S10 signature. ArrsGAqvsGPIpLPT |
| Chain | Residue | Details |
| 1j | ALA27-THR42 |
| site_id | PS00362 |
| Number of Residues | 31 |
| Details | RIBOSOMAL_S15 Ribosomal protein S15 signature. LseHLkvhKkDhhShrgLlmMvgqrrrLlrY |
| Chain | Residue | Details |
| 1o | LEU39-TYR69 |
| site_id | PS00464 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_L22 Ribosomal protein L22 signature. KrvLpRArGRadiikkrtSHITViL |
| Chain | Residue | Details |
| 1W | LYS83-LEU107 |
| site_id | PS00467 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_L2 Ribosomal protein L2 signature. PhvRGAAmNPvD |
| Chain | Residue | Details |
| 1D | PRO219-ASP230 |
| site_id | PS00474 |
| Number of Residues | 24 |
| Details | RIBOSOMAL_L3 Ribosomal protein L3 signature. FkpgervDvtGtSkGRGfaGvmkR |
| Chain | Residue | Details |
| 1E | PHE96-ARG119 |
| site_id | PS00475 |
| Number of Residues | 30 |
| Details | RIBOSOMAL_L15 Ribosomal protein L15 signature. KILGeGeAkp...LkVvahaFSksAlekLkaaG |
| Chain | Residue | Details |
| 1P | LYS113-GLY142 |
| site_id | PS00527 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CvrcgrarsvyrfFGLCRiCLR |
| Chain | Residue | Details |
| 1n | ARG23-ARG45 |
| site_id | PS00548 |
| Number of Residues | 35 |
| Details | RIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewaaqGrVplHt..LranIDygfalarTtyGvlG |
| Chain | Residue | Details |
| 1c | ALA163-GLY197 |
| site_id | PS00579 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L29 Ribosomal protein L29 signature. QNHKIRdLKRQIARL |
| Chain | Residue | Details |
| 22 | GLN46-LEU60 |
| site_id | PS00582 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L33 Ribosomal protein L33 signature. YaTeKNkrntPnkLElrKYC |
| Chain | Residue | Details |
| 16 | TYR21-CYS40 |
| site_id | PS00585 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_S5 Ribosomal protein S5 signature. GRrfrFgAlvVVGDrq.GrVGlGfgkap.EVpl.AV |
| Chain | Residue | Details |
| 1e | GLY23-VAL55 |
| site_id | PS00632 |
| Number of Residues | 25 |
| Details | RIBOSOMAL_S4 Ribosomal protein S4 signature. LEsRLdnvVYRlgfAvSrrqARqLV |
| Chain | Residue | Details |
| 1d | LEU97-VAL121 |
| site_id | PS00634 |
| Number of Residues | 33 |
| Details | RIBOSOMAL_L30 Ribosomal protein L30 signature. ALkaLgLrRlqQeRvledtpairgNVekVahLV |
| Chain | Residue | Details |
| 23 | ALA22-VAL54 |
| site_id | PS00646 |
| Number of Residues | 14 |
| Details | RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ |
| Chain | Residue | Details |
| 1m | ARG88-GLN101 |
| site_id | PS00651 |
| Number of Residues | 28 |
| Details | RIBOSOMAL_L9 Ribosomal protein L9 signature. GdvGqvvdVkpGYarNYLlprglAvlaT |
| Chain | Residue | Details |
| 1I | GLY13-THR40 |
| site_id | PS00783 |
| Number of Residues | 23 |
| Details | RIBOSOMAL_L13 Ribosomal protein L13 signature. VKGMLPkgpl.GRrlfkrLkVYaG |
| Chain | Residue | Details |
| 1N | VAL103-GLY125 |
| site_id | PS00784 |
| Number of Residues | 20 |
| Details | RIBOSOMAL_L34 Ribosomal protein L34 signature. KRTWQpnrrkRakth.GFraR |
| Chain | Residue | Details |
| 17 | LYS2-ARG21 |
| site_id | PS00828 |
| Number of Residues | 26 |
| Details | RIBOSOMAL_L36 Ribosomal protein L36 signature. CdkCkvIrRhgrVyViCenp.KHkQrQ |
| Chain | Residue | Details |
| 19 | CYS11-GLN36 |
| site_id | PS00831 |
| Number of Residues | 15 |
| Details | RIBOSOMAL_L27 Ribosomal protein L27 signature. GnILvRQRGtrfkpG |
| Chain | Residue | Details |
| 10 | GLY34-GLY48 |
| site_id | PS00936 |
| Number of Residues | 27 |
| Details | RIBOSOMAL_L35 Ribosomal protein L35 signature. KTHkGAkKRVkitasgkvvamktgk.RH |
| Chain | Residue | Details |
| 18 | LYS5-HIS31 |
| site_id | PS00937 |
| Number of Residues | 17 |
| Details | RIBOSOMAL_L20 Ribosomal protein L20 signature. KrdfRrLWIVRINaacR |
| Chain | Residue | Details |
| 1U | LYS54-ARG70 |
| site_id | PS00962 |
| Number of Residues | 12 |
| Details | RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VkELLEAGVHFG |
| Chain | Residue | Details |
| 1b | VAL7-GLY18 |
| site_id | PS01015 |
| Number of Residues | 16 |
| Details | RIBOSOMAL_L19 Ribosomal protein L19 signature. IvQrGRAR.RAKLYFIR |
| Chain | Residue | Details |
| 1T | ILE88-ARG103 |
| site_id | PS01048 |
| Number of Residues | 10 |
| Details | RIBOSOMAL_S6 Ribosomal protein S6 signature. GlRRLAYpIA |
| Chain | Residue | Details |
| 1f | GLY44-ALA53 |
| site_id | PS01108 |
| Number of Residues | 18 |
| Details | RIBOSOMAL_L24 Ribosomal protein L24 signature. GDtVlVAsGkyKGrv.GkV |
| Chain | Residue | Details |
| 1Y | GLY10-VAL27 |
| site_id | PS01143 |
| Number of Residues | 22 |
| Details | RIBOSOMAL_L31 Ribosomal protein L31 signature. EVcskcHPFYTgqqrfvdte....GR |
| Chain | Residue | Details |
| 24 | GLU34-ARG55 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11866529 |
| Chain | Residue | Details |
| 1n | CYS24 | |
| 1n | CYS27 | |
| 1n | CYS40 | |
| 1n | CYS43 | |
| 2n | CYS24 | |
| 2n | CYS27 | |
| 2n | CYS40 | |
| 2n | CYS43 |
