8VME
Crystal structure of the GSK-3/Axin complex bound to a phosphorylated beta-catenin T41A peptide
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 25 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGNGSFGVVYqAklcdsgelv.........AIKK |
| Chain | Residue | Details |
| A | ILE62-LYS86 |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IcHrDIKpqNLLL |
| Chain | Residue | Details |
| A | ILE177-LEU189 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by GSK3-beta and HIPK2 => ECO:0000269|PubMed:20307497 |
| Chain | Residue | Details |
| C | SER37 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by GSK3-beta => ECO:0000269|PubMed:12027456 |
| Chain | Residue | Details |
| C | ALA41 | |
| A | LYS85 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:12051714 |
| Chain | Residue | Details |
| C | SEP45 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:24824780 |
| Chain | Residue | Details |
| C | LYS49 |
