8VLD
Crystal structure of Ash1L PHD finger in complex with histone H3K4me2
Functional Information from PROSITE/UniProt
| site_id | PS01359 |
| Number of Residues | 41 |
| Details | ZF_PHD_1 Zinc finger PHD-type signature. Ci.Cglykdeglm....................................IqCdk..Cmvw.QHcdCmgvnsdveh....................................YlCeqC |
| Chain | Residue | Details |
| A | CYS8-CYS48 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Citrulline; alternate => ECO:0000250|UniProtKB:P84243 |
| Chain | Residue | Details |
| T | ARG2 | |
| P | ARG2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by HASPIN => ECO:0000250|UniProtKB:P68431 |
| Chain | Residue | Details |
| T | THR3 | |
| P | THR3 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000250|UniProtKB:P68431 |
| Chain | Residue | Details |
| T | MLY4 | |
| P | MLY4 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: 5-glutamyl serotonin; alternate => ECO:0000250|UniProtKB:P68431 |
| Chain | Residue | Details |
| T | GLN5 | |
| P | GLN5 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000250|UniProtKB:P68431 |
| Chain | Residue | Details |
| T | THR6 | |
| T | THR11 | |
| P | THR6 | |
| P | THR11 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250|UniProtKB:P68433 |
| Chain | Residue | Details |
| T | ARG8 | |
| P | ARG8 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000250|UniProtKB:P68432 |
| Chain | Residue | Details |
| T | LYS9 | |
| P | LYS9 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000250|UniProtKB:P68432 |
| Chain | Residue | Details |
| T | SER10 | |
| P | SER10 |
