8VI2
TehA from Haemophilus influenzae purified in DDM
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005886 | cellular_component | plasma membrane |
A | 0016020 | cellular_component | membrane |
A | 0034220 | biological_process | monoatomic ion transmembrane transport |
A | 0042802 | molecular_function | identical protein binding |
A | 0046583 | molecular_function | monoatomic cation efflux transmembrane transporter activity |
A | 0046677 | biological_process | response to antibiotic |
A | 0046690 | biological_process | response to tellurium ion |
A | 0055085 | biological_process | transmembrane transport |
A | 0098655 | biological_process | monoatomic cation transmembrane transport |
B | 0005886 | cellular_component | plasma membrane |
B | 0016020 | cellular_component | membrane |
B | 0034220 | biological_process | monoatomic ion transmembrane transport |
B | 0042802 | molecular_function | identical protein binding |
B | 0046583 | molecular_function | monoatomic cation efflux transmembrane transporter activity |
B | 0046677 | biological_process | response to antibiotic |
B | 0046690 | biological_process | response to tellurium ion |
B | 0055085 | biological_process | transmembrane transport |
B | 0098655 | biological_process | monoatomic cation transmembrane transport |
C | 0005886 | cellular_component | plasma membrane |
C | 0016020 | cellular_component | membrane |
C | 0034220 | biological_process | monoatomic ion transmembrane transport |
C | 0042802 | molecular_function | identical protein binding |
C | 0046583 | molecular_function | monoatomic cation efflux transmembrane transporter activity |
C | 0046677 | biological_process | response to antibiotic |
C | 0046690 | biological_process | response to tellurium ion |
C | 0055085 | biological_process | transmembrane transport |
C | 0098655 | biological_process | monoatomic cation transmembrane transport |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 675 |
Details | TRANSMEM: Helical |
Chain | Residue | Details |
A | PRO8-PHE28 | |
A | GLN281-THR307 | |
B | PRO8-PHE28 | |
B | ALA36-TYR59 | |
B | PHE80-TYR98 | |
B | PRO102-LEU127 | |
B | PRO140-LEU160 | |
B | HIS163-ILE190 | |
B | PRO195-ILE218 | |
B | THR225-ILE248 | |
B | ILE255-TYR275 | |
A | ALA36-TYR59 | |
B | GLN281-THR307 | |
C | PRO8-PHE28 | |
C | ALA36-TYR59 | |
C | PHE80-TYR98 | |
C | PRO102-LEU127 | |
C | PRO140-LEU160 | |
C | HIS163-ILE190 | |
C | PRO195-ILE218 | |
C | THR225-ILE248 | |
C | ILE255-TYR275 | |
A | PHE80-TYR98 | |
C | GLN281-THR307 | |
A | PRO102-LEU127 | |
A | PRO140-LEU160 | |
A | HIS163-ILE190 | |
A | PRO195-ILE218 | |
A | THR225-ILE248 | |
A | ILE255-TYR275 |
site_id | SWS_FT_FI2 |
Number of Residues | 54 |
Details | TOPO_DOM: Periplasmic => ECO:0000305 |
Chain | Residue | Details |
A | HIS29-PRO35 | |
B | HIS276-LEU280 | |
C | HIS29-PRO35 | |
C | ARG99-ASN101 | |
C | GLY161-TYR162 | |
C | ASN219-ASP224 | |
C | HIS276-LEU280 | |
A | ARG99-ASN101 | |
A | GLY161-TYR162 | |
A | ASN219-ASP224 | |
A | HIS276-LEU280 | |
B | HIS29-PRO35 | |
B | ARG99-ASN101 | |
B | GLY161-TYR162 | |
B | ASN219-ASP224 |
site_id | SWS_FT_FI3 |
Number of Residues | 132 |
Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
Chain | Residue | Details |
A | ALA60-ARG79 | |
B | LYS308-LYS314 | |
C | ALA60-ARG79 | |
C | TRP128-HIS139 | |
C | SER191-GLU194 | |
C | VAL249-ASN254 | |
C | LYS308-LYS314 | |
A | TRP128-HIS139 | |
A | SER191-GLU194 | |
A | VAL249-ASN254 | |
A | LYS308-LYS314 | |
B | ALA60-ARG79 | |
B | TRP128-HIS139 | |
B | SER191-GLU194 | |
B | VAL249-ASN254 |
site_id | SWS_FT_FI4 |
Number of Residues | 3 |
Details | SITE: Important for gating; obstructs channel and prevents ion flux in the closed conformation |
Chain | Residue | Details |
A | PHE262 | |
B | PHE262 | |
C | PHE262 |