8UQV

Trehalose Synthase (TreS) of Mycobacterium tuberculosis in complex with 6-TreAz compound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000272	biological_process	polysaccharide catabolic process
A	0004556	molecular_function	alpha-amylase activity
A	0005978	biological_process	glycogen biosynthetic process
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016853	molecular_function	isomerase activity
A	0045227	biological_process	capsule polysaccharide biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0047471	molecular_function	maltose alpha-D-glucosyltransferase activity
B	0000272	biological_process	polysaccharide catabolic process
B	0004556	molecular_function	alpha-amylase activity
B	0005978	biological_process	glycogen biosynthetic process
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0016853	molecular_function	isomerase activity
B	0045227	biological_process	capsule polysaccharide biosynthetic process
B	0046872	molecular_function	metal ion binding
B	0047471	molecular_function	maltose alpha-D-glucosyltransferase activity
C	0000272	biological_process	polysaccharide catabolic process
C	0004556	molecular_function	alpha-amylase activity
C	0005978	biological_process	glycogen biosynthetic process
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0016853	molecular_function	isomerase activity
C	0045227	biological_process	capsule polysaccharide biosynthetic process
C	0046872	molecular_function	metal ion binding
C	0047471	molecular_function	maltose alpha-D-glucosyltransferase activity
D	0000272	biological_process	polysaccharide catabolic process
D	0004556	molecular_function	alpha-amylase activity
D	0005978	biological_process	glycogen biosynthetic process
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0016853	molecular_function	isomerase activity
D	0045227	biological_process	capsule polysaccharide biosynthetic process
D	0046872	molecular_function	metal ion binding
D	0047471	molecular_function	maltose alpha-D-glucosyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000250|UniProtKB:A0R6E0

Chain	Residue	Details
A	ALA238
B	ALA238
C	ALA238
D	ALA238

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:Q9ZEU2

Chain	Residue	Details
A	GLU280
B	GLU280
C	GLU280
D	GLU280

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9ZEU2

Chain	Residue	Details
A	ASP98
B	ARG236
B	HIS349
B	ASP350
C	ASP98
C	HIS141
C	GLN206
C	ARG236
C	HIS349
C	ASP350
D	ASP98
A	HIS141
D	HIS141
D	GLN206
D	ARG236
D	HIS349
D	ASP350
A	GLN206
A	ARG236
A	HIS349
A	ASP350
B	ASP98
B	HIS141
B	GLN206

---

site_id	SWS_FT_FI4
Number of Residues	20
Details	BINDING: BINDING => ECO:0000250|UniProtKB:A0R6E0

Chain	Residue	Details
A	ASN140
B	GLU245
C	ASN140
C	ASP208
C	TYR242
C	LEU243
C	GLU245
D	ASN140
D	ASP208
D	TYR242
D	LEU243
A	ASP208
D	GLU245
A	TYR242
A	LEU243
A	GLU245
B	ASN140
B	ASP208
B	TYR242
B	LEU243

---