8UJD

In situ human 60S ribosome with eIF6

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
CA	0003676	molecular_function	nucleic acid binding
CA	0003714	molecular_function	transcription corepressor activity
CA	0003723	molecular_function	RNA binding
CA	0005515	molecular_function	protein binding
CA	0005576	cellular_component	extracellular region
CA	0005634	cellular_component	nucleus
CA	0005730	cellular_component	nucleolus
CA	0005737	cellular_component	cytoplasm
CA	0006364	biological_process	rRNA processing
CA	0006417	biological_process	regulation of translation
CA	0016020	cellular_component	membrane
CA	0031625	molecular_function	ubiquitin protein ligase binding
CA	0035578	cellular_component	azurophil granule lumen
CA	0043066	biological_process	negative regulation of apoptotic process
CA	0045597	biological_process	positive regulation of cell differentiation
CA	0045892	biological_process	negative regulation of DNA-templated transcription
CA	0070062	cellular_component	extracellular exosome
CA	1990904	cellular_component	ribonucleoprotein complex
LA	0002181	biological_process	cytoplasmic translation
LA	0003723	molecular_function	RNA binding
LA	0003735	molecular_function	structural constituent of ribosome
LA	0005515	molecular_function	protein binding
LA	0005654	cellular_component	nucleoplasm
LA	0005737	cellular_component	cytoplasm
LA	0005829	cellular_component	cytosol
LA	0005840	cellular_component	ribosome
LA	0005925	cellular_component	focal adhesion
LA	0006412	biological_process	translation
LA	0014069	cellular_component	postsynaptic density
LA	0016020	cellular_component	membrane
LA	0019843	molecular_function	rRNA binding
LA	0022625	cellular_component	cytosolic large ribosomal subunit
LA	0022626	cellular_component	cytosolic ribosome
LA	0045202	cellular_component	synapse
LA	0098794	cellular_component	postsynapse
LA	1990904	cellular_component	ribonucleoprotein complex
LB	0002181	biological_process	cytoplasmic translation
LB	0003723	molecular_function	RNA binding
LB	0003735	molecular_function	structural constituent of ribosome
LB	0005515	molecular_function	protein binding
LB	0005634	cellular_component	nucleus
LB	0005730	cellular_component	nucleolus
LB	0005737	cellular_component	cytoplasm
LB	0005829	cellular_component	cytosol
LB	0005840	cellular_component	ribosome
LB	0005925	cellular_component	focal adhesion
LB	0006412	biological_process	translation
LB	0022625	cellular_component	cytosolic large ribosomal subunit
LB	0022626	cellular_component	cytosolic ribosome
LB	0032991	cellular_component	protein-containing complex
LB	0070062	cellular_component	extracellular exosome
LB	0071353	biological_process	cellular response to interleukin-4
LB	1990904	cellular_component	ribonucleoprotein complex
LD	0000027	biological_process	ribosomal large subunit assembly
LD	0002181	biological_process	cytoplasmic translation
LD	0003723	molecular_function	RNA binding
LD	0003730	molecular_function	mRNA 3'-UTR binding
LD	0003735	molecular_function	structural constituent of ribosome
LD	0005515	molecular_function	protein binding
LD	0005634	cellular_component	nucleus
LD	0005654	cellular_component	nucleoplasm
LD	0005730	cellular_component	nucleolus
LD	0005737	cellular_component	cytoplasm
LD	0005783	cellular_component	endoplasmic reticulum
LD	0005829	cellular_component	cytosol
LD	0005840	cellular_component	ribosome
LD	0005925	cellular_component	focal adhesion
LD	0006364	biological_process	rRNA processing
LD	0006412	biological_process	translation
LD	0008097	molecular_function	5S rRNA binding
LD	0010628	biological_process	positive regulation of gene expression
LD	0016020	cellular_component	membrane
LD	0019843	molecular_function	rRNA binding
LD	0022625	cellular_component	cytosolic large ribosomal subunit
LD	0022626	cellular_component	cytosolic ribosome
LD	0031625	molecular_function	ubiquitin protein ligase binding
LD	0032991	cellular_component	protein-containing complex
LD	0042273	biological_process	ribosomal large subunit biogenesis
LD	0045727	biological_process	positive regulation of translation
LD	0048027	molecular_function	mRNA 5'-UTR binding
LD	0050821	biological_process	protein stabilization
LD	0070062	cellular_component	extracellular exosome
LD	1901796	biological_process	regulation of signal transduction by p53 class mediator
LD	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
LD	1990904	cellular_component	ribonucleoprotein complex
LD	1990948	molecular_function	ubiquitin ligase inhibitor activity
LD	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
LD	2000435	biological_process	negative regulation of protein neddylation
LF	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LF	0002181	biological_process	cytoplasmic translation
LF	0003677	molecular_function	DNA binding
LF	0003723	molecular_function	RNA binding
LF	0003729	molecular_function	mRNA binding
LF	0003735	molecular_function	structural constituent of ribosome
LF	0005515	molecular_function	protein binding
LF	0005634	cellular_component	nucleus
LF	0005730	cellular_component	nucleolus
LF	0005737	cellular_component	cytoplasm
LF	0005783	cellular_component	endoplasmic reticulum
LF	0005829	cellular_component	cytosol
LF	0005840	cellular_component	ribosome
LF	0005925	cellular_component	focal adhesion
LF	0006364	biological_process	rRNA processing
LF	0006412	biological_process	translation
LF	0014069	cellular_component	postsynaptic density
LF	0016020	cellular_component	membrane
LF	0022625	cellular_component	cytosolic large ribosomal subunit
LF	0022626	cellular_component	cytosolic ribosome
LF	0042273	biological_process	ribosomal large subunit biogenesis
LF	0042802	molecular_function	identical protein binding
LF	1990904	cellular_component	ribonucleoprotein complex
LG	0000470	biological_process	maturation of LSU-rRNA
LG	0002181	biological_process	cytoplasmic translation
LG	0003723	molecular_function	RNA binding
LG	0003735	molecular_function	structural constituent of ribosome
LG	0005515	molecular_function	protein binding
LG	0005634	cellular_component	nucleus
LG	0005730	cellular_component	nucleolus
LG	0005737	cellular_component	cytoplasm
LG	0005829	cellular_component	cytosol
LG	0005840	cellular_component	ribosome
LG	0005925	cellular_component	focal adhesion
LG	0006412	biological_process	translation
LG	0016020	cellular_component	membrane
LG	0022625	cellular_component	cytosolic large ribosomal subunit
LG	0022626	cellular_component	cytosolic ribosome
LG	0045202	cellular_component	synapse
LG	0045296	molecular_function	cadherin binding
LG	1990904	cellular_component	ribonucleoprotein complex
LH	0002181	biological_process	cytoplasmic translation
LH	0003723	molecular_function	RNA binding
LH	0003735	molecular_function	structural constituent of ribosome
LH	0005515	molecular_function	protein binding
LH	0005634	cellular_component	nucleus
LH	0005737	cellular_component	cytoplasm
LH	0005829	cellular_component	cytosol
LH	0005840	cellular_component	ribosome
LH	0005925	cellular_component	focal adhesion
LH	0006412	biological_process	translation
LH	0016020	cellular_component	membrane
LH	0022625	cellular_component	cytosolic large ribosomal subunit
LH	0022626	cellular_component	cytosolic ribosome
LH	1990904	cellular_component	ribonucleoprotein complex
LI	0000027	biological_process	ribosomal large subunit assembly
LI	0003735	molecular_function	structural constituent of ribosome
LI	0005634	cellular_component	nucleus
LI	0005737	cellular_component	cytoplasm
LI	0005783	cellular_component	endoplasmic reticulum
LI	0005829	cellular_component	cytosol
LI	0005840	cellular_component	ribosome
LI	0006412	biological_process	translation
LI	0007141	biological_process	male meiosis I
LI	0007283	biological_process	spermatogenesis
LI	0016020	cellular_component	membrane
LI	0022625	cellular_component	cytosolic large ribosomal subunit
LI	0030154	biological_process	cell differentiation
LI	0051321	biological_process	meiotic cell cycle
LI	1990904	cellular_component	ribonucleoprotein complex
LJ	0000027	biological_process	ribosomal large subunit assembly
LJ	0002181	biological_process	cytoplasmic translation
LJ	0003723	molecular_function	RNA binding
LJ	0003735	molecular_function	structural constituent of ribosome
LJ	0005515	molecular_function	protein binding
LJ	0005634	cellular_component	nucleus
LJ	0005654	cellular_component	nucleoplasm
LJ	0005730	cellular_component	nucleolus
LJ	0005737	cellular_component	cytoplasm
LJ	0005829	cellular_component	cytosol
LJ	0005840	cellular_component	ribosome
LJ	0006364	biological_process	rRNA processing
LJ	0006412	biological_process	translation
LJ	0006605	biological_process	protein targeting
LJ	0008097	molecular_function	5S rRNA binding
LJ	0010628	biological_process	positive regulation of gene expression
LJ	0016020	cellular_component	membrane
LJ	0019843	molecular_function	rRNA binding
LJ	0022625	cellular_component	cytosolic large ribosomal subunit
LJ	0022626	cellular_component	cytosolic ribosome
LJ	0031625	molecular_function	ubiquitin protein ligase binding
LJ	0032092	biological_process	positive regulation of protein binding
LJ	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
LJ	0032991	cellular_component	protein-containing complex
LJ	0034504	biological_process	protein localization to nucleus
LJ	0042273	biological_process	ribosomal large subunit biogenesis
LJ	0050821	biological_process	protein stabilization
LJ	0070062	cellular_component	extracellular exosome
LJ	1901796	biological_process	regulation of signal transduction by p53 class mediator
LJ	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
LJ	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
LJ	1990904	cellular_component	ribonucleoprotein complex
LJ	1990948	molecular_function	ubiquitin ligase inhibitor activity
LJ	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
LJ	2000435	biological_process	negative regulation of protein neddylation
LL	0001824	biological_process	blastocyst development
LL	0002181	biological_process	cytoplasmic translation
LL	0003723	molecular_function	RNA binding
LL	0003735	molecular_function	structural constituent of ribosome
LL	0005515	molecular_function	protein binding
LL	0005634	cellular_component	nucleus
LL	0005730	cellular_component	nucleolus
LL	0005737	cellular_component	cytoplasm
LL	0005783	cellular_component	endoplasmic reticulum
LL	0005829	cellular_component	cytosol
LL	0005840	cellular_component	ribosome
LL	0006412	biological_process	translation
LL	0016020	cellular_component	membrane
LL	0022625	cellular_component	cytosolic large ribosomal subunit
LL	0022626	cellular_component	cytosolic ribosome
LL	0045202	cellular_component	synapse
LL	0060348	biological_process	bone development
LL	1990904	cellular_component	ribonucleoprotein complex
LN	0002181	biological_process	cytoplasmic translation
LN	0003723	molecular_function	RNA binding
LN	0003735	molecular_function	structural constituent of ribosome
LN	0005515	molecular_function	protein binding
LN	0005634	cellular_component	nucleus
LN	0005737	cellular_component	cytoplasm
LN	0005829	cellular_component	cytosol
LN	0005840	cellular_component	ribosome
LN	0006412	biological_process	translation
LN	0022625	cellular_component	cytosolic large ribosomal subunit
LN	0022626	cellular_component	cytosolic ribosome
LN	0044391	cellular_component	ribosomal subunit
LN	0045202	cellular_component	synapse
LN	0045296	molecular_function	cadherin binding
LN	1990904	cellular_component	ribonucleoprotein complex
LO	0002181	biological_process	cytoplasmic translation
LO	0003723	molecular_function	RNA binding
LO	0003729	molecular_function	mRNA binding
LO	0003735	molecular_function	structural constituent of ribosome
LO	0005634	cellular_component	nucleus
LO	0005730	cellular_component	nucleolus
LO	0005737	cellular_component	cytoplasm
LO	0005829	cellular_component	cytosol
LO	0005840	cellular_component	ribosome
LO	0005925	cellular_component	focal adhesion
LO	0006412	biological_process	translation
LO	0006417	biological_process	regulation of translation
LO	0015934	cellular_component	large ribosomal subunit
LO	0016020	cellular_component	membrane
LO	0017148	biological_process	negative regulation of translation
LO	0022625	cellular_component	cytosolic large ribosomal subunit
LO	0022626	cellular_component	cytosolic ribosome
LO	0032496	biological_process	response to lipopolysaccharide
LO	0032819	biological_process	positive regulation of natural killer cell proliferation
LO	0042592	biological_process	homeostatic process
LO	0045202	cellular_component	synapse
LO	0048246	biological_process	macrophage chemotaxis
LO	0060425	biological_process	lung morphogenesis
LO	0071346	biological_process	cellular response to type II interferon
LO	0097452	cellular_component	GAIT complex
LO	1901194	biological_process	negative regulation of formation of translation preinitiation complex
LO	1990904	cellular_component	ribonucleoprotein complex
LQ	0002181	biological_process	cytoplasmic translation
LQ	0003723	molecular_function	RNA binding
LQ	0003735	molecular_function	structural constituent of ribosome
LQ	0005515	molecular_function	protein binding
LQ	0005634	cellular_component	nucleus
LQ	0005730	cellular_component	nucleolus
LQ	0005737	cellular_component	cytoplasm
LQ	0005783	cellular_component	endoplasmic reticulum
LQ	0005791	cellular_component	rough endoplasmic reticulum
LQ	0005829	cellular_component	cytosol
LQ	0005840	cellular_component	ribosome
LQ	0005925	cellular_component	focal adhesion
LQ	0006412	biological_process	translation
LQ	0016020	cellular_component	membrane
LQ	0022625	cellular_component	cytosolic large ribosomal subunit
LQ	0022626	cellular_component	cytosolic ribosome
LQ	1990904	cellular_component	ribonucleoprotein complex
LR	0002181	biological_process	cytoplasmic translation
LR	0003723	molecular_function	RNA binding
LR	0003735	molecular_function	structural constituent of ribosome
LR	0005515	molecular_function	protein binding
LR	0005730	cellular_component	nucleolus
LR	0005737	cellular_component	cytoplasm
LR	0005829	cellular_component	cytosol
LR	0005840	cellular_component	ribosome
LR	0005925	cellular_component	focal adhesion
LR	0006412	biological_process	translation
LR	0016020	cellular_component	membrane
LR	0022625	cellular_component	cytosolic large ribosomal subunit
LR	0022626	cellular_component	cytosolic ribosome
LR	0045202	cellular_component	synapse
LR	1990904	cellular_component	ribonucleoprotein complex
LS	0002181	biological_process	cytoplasmic translation
LS	0003723	molecular_function	RNA binding
LS	0003735	molecular_function	structural constituent of ribosome
LS	0005515	molecular_function	protein binding
LS	0005737	cellular_component	cytoplasm
LS	0005829	cellular_component	cytosol
LS	0005840	cellular_component	ribosome
LS	0006412	biological_process	translation
LS	0014069	cellular_component	postsynaptic density
LS	0016020	cellular_component	membrane
LS	0022625	cellular_component	cytosolic large ribosomal subunit
LS	0022626	cellular_component	cytosolic ribosome
LS	1990904	cellular_component	ribonucleoprotein complex
LT	0002181	biological_process	cytoplasmic translation
LT	0003723	molecular_function	RNA binding
LT	0003735	molecular_function	structural constituent of ribosome
LT	0005515	molecular_function	protein binding
LT	0005737	cellular_component	cytoplasm
LT	0005783	cellular_component	endoplasmic reticulum
LT	0005829	cellular_component	cytosol
LT	0005840	cellular_component	ribosome
LT	0006412	biological_process	translation
LT	0016020	cellular_component	membrane
LT	0022625	cellular_component	cytosolic large ribosomal subunit
LT	0022626	cellular_component	cytosolic ribosome
LT	0045202	cellular_component	synapse
LT	1990904	cellular_component	ribonucleoprotein complex
LV	0000122	biological_process	negative regulation of transcription by RNA polymerase II
LV	0001223	molecular_function	transcription coactivator binding
LV	0002181	biological_process	cytoplasmic translation
LV	0003723	molecular_function	RNA binding
LV	0003735	molecular_function	structural constituent of ribosome
LV	0005515	molecular_function	protein binding
LV	0005654	cellular_component	nucleoplasm
LV	0005730	cellular_component	nucleolus
LV	0005737	cellular_component	cytoplasm
LV	0005829	cellular_component	cytosol
LV	0005840	cellular_component	ribosome
LV	0005925	cellular_component	focal adhesion
LV	0006412	biological_process	translation
LV	0006610	biological_process	ribosomal protein import into nucleus
LV	0008284	biological_process	positive regulation of cell population proliferation
LV	0010628	biological_process	positive regulation of gene expression
LV	0015934	cellular_component	large ribosomal subunit
LV	0016020	cellular_component	membrane
LV	0022625	cellular_component	cytosolic large ribosomal subunit
LV	0022626	cellular_component	cytosolic ribosome
LV	0031625	molecular_function	ubiquitin protein ligase binding
LV	0032986	biological_process	protein-DNA complex disassembly
LV	0032991	cellular_component	protein-containing complex
LV	0045202	cellular_component	synapse
LV	0050821	biological_process	protein stabilization
LV	0070062	cellular_component	extracellular exosome
LV	0070180	molecular_function	large ribosomal subunit rRNA binding
LV	0070314	biological_process	G1 to G0 transition
LV	0072717	biological_process	cellular response to actinomycin D
LV	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
LV	1903450	biological_process	regulation of G1 to G0 transition
LV	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
LV	1990904	cellular_component	ribonucleoprotein complex
LV	1990948	molecular_function	ubiquitin ligase inhibitor activity
LV	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
LY	0002181	biological_process	cytoplasmic translation
LY	0003723	molecular_function	RNA binding
LY	0003735	molecular_function	structural constituent of ribosome
LY	0005515	molecular_function	protein binding
LY	0005654	cellular_component	nucleoplasm
LY	0005730	cellular_component	nucleolus
LY	0005737	cellular_component	cytoplasm
LY	0005829	cellular_component	cytosol
LY	0005840	cellular_component	ribosome
LY	0006364	biological_process	rRNA processing
LY	0006412	biological_process	translation
LY	0016020	cellular_component	membrane
LY	0022625	cellular_component	cytosolic large ribosomal subunit
LY	0022626	cellular_component	cytosolic ribosome
LY	0030330	biological_process	DNA damage response, signal transduction by p53 class mediator
LY	0034644	biological_process	cellular response to UV
LY	0042273	biological_process	ribosomal large subunit biogenesis
LY	0043517	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator
LY	0045727	biological_process	positive regulation of translation
LY	0048027	molecular_function	mRNA 5'-UTR binding
LY	0070062	cellular_component	extracellular exosome
LY	0071480	biological_process	cellular response to gamma radiation
LY	1902167	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
LY	1904803	biological_process	regulation of translation involved in cellular response to UV
LY	1990904	cellular_component	ribonucleoprotein complex
LZ	0002181	biological_process	cytoplasmic translation
LZ	0003723	molecular_function	RNA binding
LZ	0003735	molecular_function	structural constituent of ribosome
LZ	0005515	molecular_function	protein binding
LZ	0005634	cellular_component	nucleus
LZ	0005654	cellular_component	nucleoplasm
LZ	0005730	cellular_component	nucleolus
LZ	0005737	cellular_component	cytoplasm
LZ	0005783	cellular_component	endoplasmic reticulum
LZ	0005791	cellular_component	rough endoplasmic reticulum
LZ	0005829	cellular_component	cytosol
LZ	0005840	cellular_component	ribosome
LZ	0005925	cellular_component	focal adhesion
LZ	0006364	biological_process	rRNA processing
LZ	0006412	biological_process	translation
LZ	0016020	cellular_component	membrane
LZ	0022625	cellular_component	cytosolic large ribosomal subunit
LZ	0022626	cellular_component	cytosolic ribosome
LZ	0045202	cellular_component	synapse
LZ	0070062	cellular_component	extracellular exosome
LZ	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
LZ	1990904	cellular_component	ribonucleoprotein complex
La	0002181	biological_process	cytoplasmic translation
La	0003723	molecular_function	RNA binding
La	0003735	molecular_function	structural constituent of ribosome
La	0005515	molecular_function	protein binding
La	0005654	cellular_component	nucleoplasm
La	0005737	cellular_component	cytoplasm
La	0005783	cellular_component	endoplasmic reticulum
La	0005829	cellular_component	cytosol
La	0005840	cellular_component	ribosome
La	0006412	biological_process	translation
La	0016020	cellular_component	membrane
La	0022625	cellular_component	cytosolic large ribosomal subunit
La	0022626	cellular_component	cytosolic ribosome
La	0045202	cellular_component	synapse
La	1990904	cellular_component	ribonucleoprotein complex
Le	0002181	biological_process	cytoplasmic translation
Le	0003723	molecular_function	RNA binding
Le	0003735	molecular_function	structural constituent of ribosome
Le	0005737	cellular_component	cytoplasm
Le	0005829	cellular_component	cytosol
Le	0005840	cellular_component	ribosome
Le	0006412	biological_process	translation
Le	0016020	cellular_component	membrane
Le	0022625	cellular_component	cytosolic large ribosomal subunit
Le	0022626	cellular_component	cytosolic ribosome
Le	1990904	cellular_component	ribonucleoprotein complex
Lf	0000049	molecular_function	tRNA binding
Lf	0002181	biological_process	cytoplasmic translation
Lf	0003723	molecular_function	RNA binding
Lf	0003735	molecular_function	structural constituent of ribosome
Lf	0005515	molecular_function	protein binding
Lf	0005737	cellular_component	cytoplasm
Lf	0005829	cellular_component	cytosol
Lf	0005840	cellular_component	ribosome
Lf	0006364	biological_process	rRNA processing
Lf	0006412	biological_process	translation
Lf	0016020	cellular_component	membrane
Lf	0022625	cellular_component	cytosolic large ribosomal subunit
Lf	0022626	cellular_component	cytosolic ribosome
Lf	0042273	biological_process	ribosomal large subunit biogenesis
Lf	0045202	cellular_component	synapse
Lf	0070062	cellular_component	extracellular exosome
Lf	1990904	cellular_component	ribonucleoprotein complex
Lg	0002181	biological_process	cytoplasmic translation
Lg	0003723	molecular_function	RNA binding
Lg	0003735	molecular_function	structural constituent of ribosome
Lg	0005515	molecular_function	protein binding
Lg	0005730	cellular_component	nucleolus
Lg	0005737	cellular_component	cytoplasm
Lg	0005783	cellular_component	endoplasmic reticulum
Lg	0005829	cellular_component	cytosol
Lg	0005840	cellular_component	ribosome
Lg	0006412	biological_process	translation
Lg	0022625	cellular_component	cytosolic large ribosomal subunit
Lg	0022626	cellular_component	cytosolic ribosome
Lg	0045202	cellular_component	synapse
Lg	0045296	molecular_function	cadherin binding
Lg	0070062	cellular_component	extracellular exosome
Lg	1990904	cellular_component	ribonucleoprotein complex
Lh	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Lh	0002181	biological_process	cytoplasmic translation
Lh	0003723	molecular_function	RNA binding
Lh	0003729	molecular_function	mRNA binding
Lh	0003735	molecular_function	structural constituent of ribosome
Lh	0005730	cellular_component	nucleolus
Lh	0005737	cellular_component	cytoplasm
Lh	0005829	cellular_component	cytosol
Lh	0005840	cellular_component	ribosome
Lh	0006412	biological_process	translation
Lh	0015934	cellular_component	large ribosomal subunit
Lh	0016020	cellular_component	membrane
Lh	0022625	cellular_component	cytosolic large ribosomal subunit
Lh	0022626	cellular_component	cytosolic ribosome
Lh	1990904	cellular_component	ribonucleoprotein complex
Li	0002181	biological_process	cytoplasmic translation
Li	0003723	molecular_function	RNA binding
Li	0003735	molecular_function	structural constituent of ribosome
Li	0005515	molecular_function	protein binding
Li	0005730	cellular_component	nucleolus
Li	0005737	cellular_component	cytoplasm
Li	0005829	cellular_component	cytosol
Li	0005840	cellular_component	ribosome
Li	0006412	biological_process	translation
Li	0016020	cellular_component	membrane
Li	0022625	cellular_component	cytosolic large ribosomal subunit
Li	0022626	cellular_component	cytosolic ribosome
Li	0045202	cellular_component	synapse
Li	1990904	cellular_component	ribonucleoprotein complex
Lk	0001501	biological_process	skeletal system development
Lk	0001503	biological_process	ossification
Lk	0002181	biological_process	cytoplasmic translation
Lk	0003723	molecular_function	RNA binding
Lk	0003735	molecular_function	structural constituent of ribosome
Lk	0005515	molecular_function	protein binding
Lk	0005737	cellular_component	cytoplasm
Lk	0005829	cellular_component	cytosol
Lk	0005840	cellular_component	ribosome
Lk	0005925	cellular_component	focal adhesion
Lk	0006412	biological_process	translation
Lk	0006417	biological_process	regulation of translation
Lk	0007605	biological_process	sensory perception of sound
Lk	0014069	cellular_component	postsynaptic density
Lk	0022618	biological_process	protein-RNA complex assembly
Lk	0022625	cellular_component	cytosolic large ribosomal subunit
Lk	0022626	cellular_component	cytosolic ribosome
Lk	0033291	cellular_component	eukaryotic 80S initiation complex
Lk	0034463	biological_process	90S preribosome assembly
Lk	0042474	biological_process	middle ear morphogenesis
Lk	0045202	cellular_component	synapse
Lk	0048318	biological_process	axial mesoderm development
Lk	1990904	cellular_component	ribonucleoprotein complex
Ll	0002181	biological_process	cytoplasmic translation
Ll	0002227	biological_process	innate immune response in mucosa
Ll	0003723	molecular_function	RNA binding
Ll	0003735	molecular_function	structural constituent of ribosome
Ll	0005615	cellular_component	extracellular space
Ll	0005737	cellular_component	cytoplasm
Ll	0005829	cellular_component	cytosol
Ll	0005840	cellular_component	ribosome
Ll	0006412	biological_process	translation
Ll	0019731	biological_process	antibacterial humoral response
Ll	0022625	cellular_component	cytosolic large ribosomal subunit
Ll	0022626	cellular_component	cytosolic ribosome
Ll	0050830	biological_process	defense response to Gram-positive bacterium
Ll	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
Ll	1990904	cellular_component	ribonucleoprotein complex
Lo	0002181	biological_process	cytoplasmic translation
Lo	0003723	molecular_function	RNA binding
Lo	0003735	molecular_function	structural constituent of ribosome
Lo	0005515	molecular_function	protein binding
Lo	0005737	cellular_component	cytoplasm
Lo	0005783	cellular_component	endoplasmic reticulum
Lo	0005829	cellular_component	cytosol
Lo	0005840	cellular_component	ribosome
Lo	0005886	cellular_component	plasma membrane
Lo	0006412	biological_process	translation
Lo	0022625	cellular_component	cytosolic large ribosomal subunit
Lo	0022626	cellular_component	cytosolic ribosome
Lo	1990904	cellular_component	ribonucleoprotein complex
Lp	0002181	biological_process	cytoplasmic translation
Lp	0003723	molecular_function	RNA binding
Lp	0003735	molecular_function	structural constituent of ribosome
Lp	0005515	molecular_function	protein binding
Lp	0005634	cellular_component	nucleus
Lp	0005737	cellular_component	cytoplasm
Lp	0005829	cellular_component	cytosol
Lp	0005840	cellular_component	ribosome
Lp	0005925	cellular_component	focal adhesion
Lp	0006412	biological_process	translation
Lp	0008270	molecular_function	zinc ion binding
Lp	0022625	cellular_component	cytosolic large ribosomal subunit
Lp	0022626	cellular_component	cytosolic ribosome
Lp	0045202	cellular_component	synapse
Lp	0046872	molecular_function	metal ion binding
Lp	0070062	cellular_component	extracellular exosome
Lp	1990904	cellular_component	ribonucleoprotein complex
Lr	0002181	biological_process	cytoplasmic translation
Lr	0003723	molecular_function	RNA binding
Lr	0003735	molecular_function	structural constituent of ribosome
Lr	0005515	molecular_function	protein binding
Lr	0005737	cellular_component	cytoplasm
Lr	0005829	cellular_component	cytosol
Lr	0005840	cellular_component	ribosome
Lr	0006412	biological_process	translation
Lr	0016020	cellular_component	membrane
Lr	0022625	cellular_component	cytosolic large ribosomal subunit
Lr	0022626	cellular_component	cytosolic ribosome
Lr	0030425	cellular_component	dendrite
Lr	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
Lr	0044297	cellular_component	cell body
Lr	0045202	cellular_component	synapse
Lr	0070062	cellular_component	extracellular exosome
Lr	1990904	cellular_component	ribonucleoprotein complex
P	0000054	biological_process	ribosomal subunit export from nucleus
P	0000460	biological_process	maturation of 5.8S rRNA
P	0000470	biological_process	maturation of LSU-rRNA
P	0003743	molecular_function	translation initiation factor activity
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005638	cellular_component	lamin filament
P	0005654	cellular_component	nucleoplasm
P	0005730	cellular_component	nucleolus
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005882	cellular_component	intermediate filament
P	0006110	biological_process	regulation of glycolytic process
P	0006412	biological_process	translation
P	0006413	biological_process	translational initiation
P	0032868	biological_process	response to insulin
P	0035195	biological_process	miRNA-mediated post-transcriptional gene silencing
P	0035278	biological_process	miRNA-mediated gene silencing by inhibition of translation
P	0042254	biological_process	ribosome biogenesis
P	0042256	biological_process	cytosolic ribosome assembly
P	0042273	biological_process	ribosomal large subunit biogenesis
P	0042304	biological_process	regulation of fatty acid biosynthetic process
P	0043022	molecular_function	ribosome binding
P	0043023	molecular_function	ribosomal large subunit binding
P	0045202	cellular_component	synapse
P	0045652	biological_process	regulation of megakaryocyte differentiation
P	0045727	biological_process	positive regulation of translation
P	0070062	cellular_component	extracellular exosome
P	1902626	biological_process	assembly of large subunit precursor of preribosome
P	2000377	biological_process	regulation of reactive oxygen species metabolic process

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI

Chain	Residue	Details
LV	ALA79-ILE105

---

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV

Chain	Residue	Details
LX	LYS134-VAL149

---

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR

Chain	Residue	Details
Ll	LYS30-ARG46

---

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT

Chain	Residue	Details
LJ	LEU40-THR56

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL

Chain	Residue	Details
LP	ARG126-LEU150

---

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE

Chain	Residue	Details
LA	PRO197-GLU208

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR

Chain	Residue	Details
LB	PHE211-ARG234

---

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIksvG

Chain	Residue	Details
La	LYS110-GLY141

---

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP

Chain	Residue	Details
LR	GLN7-PRO26

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV

Chain	Residue	Details
Lh	LYS43-VAL57

---

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG

Chain	Residue	Details
Le	PHE20-GLY40

---

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLrQifNgTfvklnkasinMLriVepYI

Chain	Residue	Details
LF	VAL108-ILE140

---

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV

Chain	Residue	Details
LC	GLY15-VAL22

---

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK

Chain	Residue	Details
LH	GLN163-LYS184

---

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqtLKmiRqGkaKlVIL

Chain	Residue	Details
Lc	SER24-LEU48

---

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG

Chain	Residue	Details
LO	VAL84-GLY107

---

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH

Chain	Residue	Details
LC	ASN116-HIS142

---

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLaIiDpG

Chain	Residue	Details
Lc	GLU80-GLY100

---

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGykIyPGhGrrYaRtD

Chain	Residue	Details
LW	PHE8-ASP25

---

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG

Chain	Residue	Details
Lj	GLY4-GLY23

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciIkGKarLG

Chain	Residue	Details
LG	CYS174-GLY191

---

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG

Chain	Residue	Details
LL	ARG71-GLY85

---

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP

Chain	Residue	Details
Lf	GLY72-PRO93

---

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM

Chain	Residue	Details
LQ	LYS49-MET66

---

site_id	PS01107
Number of Residues	12
Details	RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF

Chain	Residue	Details
LZ	GLY125-PHE136

---

site_id	PS01108
Number of Residues	19
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV

Chain	Residue	Details
LY	ASP52-VAL70

---

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG

Chain	Residue	Details
Ld	VAL62-GLY76

---

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TaSnKtrlsRTPGN

Chain	Residue	Details
Lg	THR15-ASN28

---

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K

Chain	Residue	Details
LE	ASN182-LYS200

---

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG

Chain	Residue	Details
LT	GLY37-GLY62

---

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLRleC

Chain	Residue	Details
Lo	LYS61-CYS72

---

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK

Chain	Residue	Details
Li	PRO52-LYS62

---

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG

Chain	Residue	Details
LN	ASP46-GLY69

---

site_id	PS01202
Number of Residues	17
Details	MAP_2 Methionine aminopeptidase subfamily 2 signature. DLvKIDlGvHVDGfiaN

Chain	Residue	Details
CA	ASP104-ASN120

---

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPqGtvARV

Chain	Residue	Details
LI	ALA108-VAL129

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
CA	SER335
Lh	LYS43
LR	ARG38

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PKC/PRKCD => ECO:0000269|PubMed:16832058, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
CA	SER361
Lp	CYS42
Lp	CYS57
Lp	CYS60

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
CA	LYS298
Lr	LYS65
LG	LYS245

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphoserine; by CK1 => ECO:0000255|HAMAP-Rule:MF_03132, ECO:0000269|PubMed:12917340, ECO:0000269|PubMed:21084295

Chain	Residue	Details
P	SER174
P	SER175

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447

Chain	Residue	Details
LS	LYS11
LB	LYS366
LJ	LYS154

---

site_id	SWS_FT_FI6
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
LL	LYS123
LS	LYS128
LS	LYS170

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733

Chain	Residue	Details
LD	LYS220
LL	LYS174
LL	LYS177
LB	LYS386
LB	LYS393

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Citrulline => ECO:0000250|UniProtKB:Q9D8E6

Chain	Residue	Details
LC	ARG300
LB	LYS399

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:Q9D8E6

Chain	Residue	Details
LC	LYS364
LB	LYS366

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:20068231

Chain	Residue	Details
LC	SER365

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
LC	LYS239
LC	LYS327

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate => ECO:0007744|PubMed:25114211

Chain	Residue	Details
LC	LYS364

---